Evidence of Presence and Activation of the two Cell Cycle Kinases Nek6 and Nek7 in the ciliated Neuroretina

Autor: Janisch Km, Stephen H. Tsang, Richard J. Davis, Kasanuki Jm

The serine/threonine NIMA kinases are widely found in eukaryotes. They are cell-cycle kinases that are associated with centrosomes and spindle apparatus and cilia. In cilia, NIMA kinases are reported to play a role in cilia length maintenance and def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bce378db5c35eeda114ac97f9dcfa8
https://doi.org/10.1101/2020.03.27.012724

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Kinesin-6 KIF20B is required for efficient cytokinetic furrowing and timely abscission in human cells.

Autor: Janisch KM; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908., McNeely KC; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908., Dardick JM; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908., Lim SH; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908., Dwyer ND; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908 ndwyer@virginia.edu.

Publikováno v: Molecular biology of the cell [Mol Biol Cell] 2018 Jan 15; Vol. 29 (2), pp. 166-179. Date of Electronic Publication: 2017 Nov 22.

Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy.

Autor: Wert KJ; Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Laboratory of Regenerative Medicine, Columbia University, New York, NY, USA; Edward S. Harkness Eye Institute, Columbia University, New York, NY, USA; Institute of Human Nutrition, Columbia University, New York, NY, USA., Mahajan VB; Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA; Omics Laboratory, University of Iowa, Iowa City, IA, USA., Zhang L; Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Laboratory of Regenerative Medicine, Columbia University, New York, NY, USA; Edward S. Harkness Eye Institute, Columbia University, New York, NY, USA., Yan Y; Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL, USA., Li Y; Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Laboratory of Regenerative Medicine, Columbia University, New York, NY, USA; Edward S. Harkness Eye Institute, Columbia University, New York, NY, USA., Tosi J; Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Laboratory of Regenerative Medicine, Columbia University, New York, NY, USA; Edward S. Harkness Eye Institute, Columbia University, New York, NY, USA., Hsu CW; Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Laboratory of Regenerative Medicine, Columbia University, New York, NY, USA; Edward S. Harkness Eye Institute, Columbia University, New York, NY, USA., Nagasaki T; Edward S. Harkness Eye Institute, Columbia University, New York, NY, USA., Janisch KM; Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Laboratory of Regenerative Medicine, Columbia University, New York, NY, USA; Edward S. Harkness Eye Institute, Columbia University, New York, NY, USA., Grant MB; Eugene and Marilyn Glick Eye Institute, Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA., Mahajan M; Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA; Omics Laboratory, University of Iowa, Iowa City, IA, USA., Bassuk AG; Department of Pediatrics, University of Iowa, Iowa City, IA, USA., Tsang SH; Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Laboratory of Regenerative Medicine, Columbia University, New York, NY, USA; Edward S. Harkness Eye Institute, Columbia University, New York, NY, USA; Institute of Human Nutrition, Columbia University, New York, NY, USA; New York Presbyterian Hospital/Columbia University Medical Center, New York, NY, USA; Department of Pathology and Cellular Biology, Columbia University, New York, NY, USA.

Publikováno v: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2016; Vol. 1. Date of Electronic Publication: 2016 Apr 22.

The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size.

Autor: Janisch KM; Department of Cell Biology, University of Virginia, Charlottesville, VA 22908, USA., Vock VM, Fleming MS, Shrestha A, Grimsley-Myers CM, Rasoul BA, Neale SA, Cupp TD, Kinchen JM, Liem KF Jr, Dwyer ND

Publikováno v: Development (Cambridge, England) [Development] 2013 Dec; Vol. 140 (23), pp. 4672-82. Date of Electronic Publication: 2013 Oct 30.