Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Janis Rambow"'
Autor:
Gerard D. Wright, Michael A. Cook, Sarah Lemcke, Arne Alder, Wenliang Wang, Min Xu, Nicole S. Struck, Jarrod W. Johnson, Janis Rambow, Daniel Pallant, Tim W. Gilberger
Publikováno v:
Cell chemical biology. 29(5)
Summary We identify a selective nanomolar inhibitor of blood-stage malarial proliferation from a screen of microbial natural product extracts. The responsible compound, PDE-I2, is a precursor of the anticancer duocarmycin family that preserves the cl
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
Frontiers in Pharmacology
Frontiers in Pharmacology
Classically, aquaporins are divided based on pore selectivity into water specific, orthodox aquaporins and solute-facilitating aquaglyceroporins, which conduct, e.g., glycerol and urea. However, more aquaporin-passing substrates have been identified
Autor:
Binghua Wu, Tobias Spielmann, Julia Holm-Bertelsen, Eric Beitz, Janis Rambow, Alexandra Blancke Soares, Sinja Bock, Marie Wiechert
Publikováno v:
Nature communications. 6
Maintenance of a high glycolytic flow rate is critical for the rapid growth and virulence of malarial parasites. The parasites release two moles of lactic acid per mole of glucose as the anaerobic end product. However, the molecular identity of the P