Výsledky vyhledávání - "Janis Poikans"

Akademický článek

Sodium N-(3,5-Bis(ethoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine-4-carbonyl)-l-methioninate

Autor: Egils Bisenieks, Janis Poikans, Aiva Plotniece, Eiva Bernotiene, Wei-Bor Tsai, Arkadij Sobolev

Publikováno v: Molbank, Vol 2020, Iss 3, p M1148 (2020)

The development of the methods for amide bond formation is important for various uses in the laboratory and industrial applications. The compounds combined in their structures 1,4-dihydroisonicotinic acids and amino acids linked with an amide bond ca

Externí odkaz: https://doaj.org/article/9682750f638449be970c9dbb74d13a0a

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Akademický článek

Antioxidative 1,4-Dihydropyridine Derivatives Modulate Oxidative Stress and Growth of Human Osteoblast-Like Cells In Vitro

Autor: Lidija Milkovic, Tea Vukovic, Neven Zarkovic, Franz Tatzber, Egils Bisenieks, Zenta Kalme, Imanta Bruvere, Zaiga Ogle, Janis Poikans, Astrida Velena, Gunars Duburs

Publikováno v: Antioxidants, Vol 7, Iss 9, p 123 (2018)

Oxidative stress has been implicated in pathophysiology of different human stress- and age-associated disorders, including osteoporosis for which antioxidants could be considered as therapeutic remedies as was suggested recently. The 1,4-dihydropyrid

Externí odkaz: https://doaj.org/article/f4a5a96db1f94324bb2f78d96f667102

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Dihydropyridine Derivatives as Cell Growth Modulators In Vitro

Autor: Martins Rucins, Marina Gosteva, Aiva Plotniece, Ilona Domracheva, Neven Zarkovic, Imanta Bruvere, Astrida Velena, Brigita Vigante, Janis Poikans, Lidija Milkovic, Tea Vuković, Gunars Duburs, J. Uldrikis, Z. A. Kalme, Egils Bisenieks, Karlis Pajuste

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)

The effects of eleven 1,4-dihydropyridine derivatives (DHPs) used alone or together with prooxidant anticancer drug doxorubicin were examined on two cancer (HOS, HeLa) and two nonmalignant cell lines (HMEC, L929). Their effects on the cell growth (3H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1ef381bd9a465ab955a7cb7d2bd9e4
https://doi.org/10.1155/2017/4069839

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GABA-containing compound gammapyrone protects against brain impairments in Alzheimer's disease model male rats and prevents mitochondrial dysfunction in cell culture

Autor: Janis Poikans, Angela Trovato, Maria Scuto, Jolanta Pupure, Vittorio Calabrese, Vija Klusa, Karina Narbute, Ines Amara, Baiba Jansone, Egils Bisenieks, Vladimirs Pilipenko

Publikováno v: Journal of neuroscience research. 97(6)

Neuroinflammation, oxidative stress, decreased glucose/energy metabolism, and disrupted neurotransmission are changes that occur early in sporadic Alzheimer's disease (AD), manifesting as mild cognitive impairment. Recently, the imbalanced function o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2417a28b067e2553bd6589e610899abf
https://pubmed.ncbi.nlm.nih.gov/30742328

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Antioxidative 1,4-Dihydropyridine Derivatives Modulate Oxidative Stress and Growth of Human Osteoblast-Like Cells In Vitro

Autor: Franz Tatzber, Imanta Bruvere, Lidija Milkovic, Z. A. Kalme, Neven Zarkovic, Gunars Duburs, Zaiga Ogle, Janis Poikans, Egils Bisenieks, Tea Vuković, Astrida Velena

Publikováno v: Antioxidants
Volume 7
Issue 9
Antioxidants, Vol 7, Iss 9, p 123 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415e79979ff38dfbb576e4b7f26ab57b

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Reactions of 9-Aroyl-3,3,6,6-Tetramethyl-1,2,3,4,5,6,7,8-Octahydroxanthene-1,8-Diones With Hydrazine and Methylhydrazine*

Autor: Janis Poikans, Marina Petrova, Gunars Duburs, J. Uldrikis, Egils Bisenieks, Edvards Liepinsh, Larisa Baumane

Publikováno v: Chemistry of Heterocyclic Compounds. 49:1653-1657

Reactions of 9-aroyl-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8-octahydroxanthene-1,8-diones with hydrazine and methylhydrazine produced cinnoline derivatives. A homolytic cleavage of C–C bond in the intermediate product occured in the case of methylhydra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57e6ce4cd843cf5b1e7532c63c4ce9cd
https://doi.org/10.1007/s10593-014-1416-4

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1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues-Model Compounds Targeting Oxidative Stress

Autor: Egils Bisenieks, Neven Zarkovic, Koraljka Gall Trošelj, Astrida Velena, Gunars Duburs, Janis Poikans, Aivars Krauze

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)

Many 1,4-dihydropyridines (DHPs) possess redox properties. In this review DHPs are surveyed as protectors against oxidative stress (OS) and related disorders, considering the DHPs as specific group of potential antioxidants with bioprotective capacit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e434fe7b0b68f586c220c49dba6953e
https://pubmed.ncbi.nlm.nih.gov/26881016

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[Untitled]

Autor: Gunars Duburs, J. Uldrikis, A. Kalnins, Egils Bisenieks, Janis Poikans, Larisa Baumane, J. Stradins

Publikováno v: Chemistry of Heterocyclic Compounds. 36:1177-1184

Electrochemical oxidation potentials of 1,4-dihydropyridines substituted with 4-COOH, 4-COOR, and 4-CONRR' groups have been determined in aprotic acetonitrile by the rotating ring-disk electrode method (RRDE). The electrochemical reduction potentials

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcfce48b2de0c74fe6e3d6708ab166f5
https://doi.org/10.1023/a:1002868600011

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