Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Janis K. Shute"'
Autor:
Thomas L. Jones, Claire Roberts, Scott Elliott, Sharon Glaysher, Ben Green, Janis K. Shute, Anoop J. Chauhan
Publikováno v:
The Clinical Respiratory Journal, Vol 18, Iss 8, Pp n/a-n/a (2024)
ABSTRACT Background and Objective COPD and bronchiectasis are common causes of morbidity, particularly around exacerbation. Colonisation with respiratory pathogens can increase the frequency and severity of exacerbations. However, bacterial and viral
Externí odkaz:
https://doaj.org/article/b704e63c4e664ca381f030d69bac497d
Autor:
Adam J. Causer, Maha Khalaf, Emily Klein Rot, Kimberly Brand, James Smith, Stephen J. Bailey, Michael H. Cummings, Anthony I. Shepherd, Zoe L. Saynor, Janis K. Shute
Publikováno v:
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Abstract Micro‐ and macrovascular endothelial dysfunction in response to shear stress has been observed in cystic fibrosis (CF), and has been associated with inflammation and oxidative stress. We tested the hypothesis that the cystic fibrosis trans
Externí odkaz:
https://doaj.org/article/15305a003efe46a2a9d40d3c7a267ada
Autor:
Adam J. Causer, Janis K. Shute, Michael H. Cummings, Anthony I. Shepherd, Mathieu Gruet, Joseph T. Costello, Stephen Bailey, Martin Lindley, Clare Pearson, Gary Connett, Mark I. Allenby, Mary P. Carroll, Thomas Daniels, Zoe L. Saynor
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Introduction: Oxidative stress may play an important role in the pathophysiology of cystic fibrosis (CF). This review aimed to quantify CF-related redox imbalances. Methods: Systematic searches of the Medline, CINAHL, CENTRAL and PsycINFO databases w
Externí odkaz:
https://doaj.org/article/8cfcf95b8b0c44f4afc9d6b25414b29e
Autor:
Adam J. Causer, Janis K. Shute, Michael H. Cummings, Anthony I. Shepherd, Samuel R. Wallbanks, Richard M. Pulsford, Victoria Bright, Gary Connett, Zoe L. Saynor
Publikováno v:
Pediatric Pulmonology. 57:2652-2658
Elexacaftor/Tezacaftor/Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator with the potential to improve exercise capacity. This case series of three adolescents with CF aimed to investigate whether 6 weeks treatment w
Autor:
Thomas Llewelyn Jones, Claire Roberts, Scott Elliott, Sharon Glaysher, Ben Green, Janis K Shute, Anoop J Chauhan
BACKGROUND COPD and bronchiectasis are common and exacerbations contribute to their morbidity and mortality. Predictive factors for frequency of future exacerbations include previous exacerbation frequency and airway colonisation. Earlier treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4cdeb3c163ad46c82cf572c1900758a
https://doi.org/10.2196/preprints.44397
https://doi.org/10.2196/preprints.44397
Autor:
Thomas Daniels, Gary Connett, Victoria Bright, Mary P. Carroll, Irantzu Arregui-Fresneda, Adam J. Causer, Tom Meredith, Mark I. Allenby, Michael H. Cummings, Zoe L. Saynor, Anthony I. Shepherd, Janis K. Shute, Samuel R. Wallbanks
Publikováno v:
Causer, A J, Shute, J, Cummings, M H, Shepherd, A, Wallbanks, S R, Allenby, M I, Arregui-Fresneda, I, Bright, V, Carroll, M P, Connett, G, Daniels, T, Meredith, T & Saynor, Z 2020, ' The implications of dysglycaemia on aerobic exercise and ventilatory function in cystic fibrosis ', Journal of Cystic Fibrosis, vol. 19, no. 3, pp. 427-433 . https://doi.org/10.1016/j.jcf.2019.09.014
Background: The development of cystic fibrosis (CF)-related diabetes (CFRD) in paediatric groups is associated with a reduced aerobic fitness. However, this has yet to be investigated in adults with more severe lung disease.Methods: Cardiopulmonary e
Autor:
Janis K. Shute, Maha Khalaf, Zoe L. Saynor, Stephen J. Bailey, Adam J. Causer, Michael H. Cummings, Emily Klein Rot, Jim T. Smith, Anthony I. Shepherd, Kimberly Brand
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Micro‐ and macrovascular endothelial dysfunction in response to shear stress has been observed in cystic fibrosis (CF), and has been associated with inflammation and oxidative stress. We tested the hypothesis that the cystic fibrosis transmembrane
Autor:
Janis K. Shute
Publikováno v:
Minerva medica. 113(1)
Biomarkers may be diagnostic of asthma, they may predict or reflect response to therapy or they may identify patients at risk of asthma exacerbation. A biomarker is most often measured in biologic fluids that are sampled using relatively non-invasive
Autor:
Christopher Corrigan, Alan L. James, Sajeel A. Shah, Yanira Riffo-Vasquez, John G. Elliot, Clive P. Page, Zainab Mohamed, Simon C. Pitchford, Varsha Kanabar, Janis K. Shute, Simon J. Cleary
Publikováno v:
Shah, S A, Kanabar, V, Riffo-Vasquez, Y, Mohamed, Z, Cleary, S J, Corrigan, C, James, A L, Elliott, J G, Shute, J K, Page, C P & Pitchford, S C 2021, ' Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3 ', American Journal of Respiratory Cell and Molecular Biology, vol. 64, no. 5, pp. 557–568 . https://doi.org/10.1165/rcmb.2020-0425OC
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology
Platelet activation and pulmonary recruitment occur in patients with asthma and in animal models of allergic asthma, in which leukocyte infiltration, airway remodeling, and hyperresponsiveness are suppressed by experimental platelet depletion. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec64117fa68f54360c906d25df93a078
https://kclpure.kcl.ac.uk/ws/files/155174783/rcmb.2020_0425oc.pdf
https://kclpure.kcl.ac.uk/ws/files/155174783/rcmb.2020_0425oc.pdf
Autor:
Alicia Vilaseca, Mary P. Carroll, Antonio Artigas, Rabab S. Mahrous, Marta Camprubí-Rimblas, Hwan-Jin Yoon, Christopher Hillman, Lex van Loon, Janis K. Shute, Barry Dixon, Miles W. Carroll, Gilberto De Nucci, Tarek I. Ismail, Mohamed Badr, Dave Singh, Frank van Haren, John G. Laffey, Anusha Belani, Carlos Eduardo Sverdloff, Clive P. Page, Tom Wilkinson, Sabrina Staas, Khine Sann, Thomas Smoot, David W. Cosgrave, Caitlin Sas, Alice Richardson, Ruben Barbera, Roger J Smith
Publikováno v:
British Journal of Clinical Pharmacology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Aims: inhaled nebulised unfractionated heparin (UFH) has a strong scientific and biological rationale that warrants urgent investigation of its therapeutic potential in patients with COVID‐19. UFH has antiviral effects and prevents the SARS‐CoV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a464917b105c48466aae2addb3270425
https://eprints.soton.ac.uk/446588/
https://eprints.soton.ac.uk/446588/