Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Janis K Shute"'
Autor:
Thomas Llewelyn Jones, Claire Roberts, Scott Elliott, Sharon Glaysher, Ben Green, Janis K Shute, Anoop J Chauhan
Publikováno v:
Interactive Journal of Medical Research, Vol 13, p e44397 (2024)
BackgroundCOPD (chronic obstructive pulmonary disease) and bronchiectasis are common, and exacerbations contribute to their morbidity and mortality. Predictive factors for the frequency of future exacerbations include previous exacerbation frequency
Externí odkaz:
https://doaj.org/article/b2d1180ebb6e405981b29cdf6b051351
Autor:
Mojgan Masoodi, Daniel S Pearl, Michael Eiden, Janis K Shute, James F Brown, Philip C Calder, Timothy M Trebble
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76532 (2013)
OBJECTIVES:Ulcerative colitis (UC) is a relapsing inflammatory disorder of unconfirmed aetiology, variable severity and clinical course, characterised by progressive histological inflammation and with elevation of eicosanoids which have a known patho
Externí odkaz:
https://doaj.org/article/28fa51e5102849a884926378d24d766e
Autor:
Adam J. Causer, Janis K. Shute, Michael H. Cummings, Anthony I. Shepherd, Samuel R. Wallbanks, Richard M. Pulsford, Victoria Bright, Gary Connett, Zoe L. Saynor
Publikováno v:
Pediatric Pulmonology. 57:2652-2658
Elexacaftor/Tezacaftor/Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator with the potential to improve exercise capacity. This case series of three adolescents with CF aimed to investigate whether 6 weeks treatment w
Autor:
Thomas Llewelyn Jones, Claire Roberts, Scott Elliott, Sharon Glaysher, Ben Green, Janis K Shute, Anoop J Chauhan
BACKGROUND COPD and bronchiectasis are common and exacerbations contribute to their morbidity and mortality. Predictive factors for frequency of future exacerbations include previous exacerbation frequency and airway colonisation. Earlier treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4cdeb3c163ad46c82cf572c1900758a
https://doi.org/10.2196/preprints.44397
https://doi.org/10.2196/preprints.44397
Autor:
Thomas Daniels, Gary Connett, Victoria Bright, Mary P. Carroll, Irantzu Arregui-Fresneda, Adam J. Causer, Tom Meredith, Mark I. Allenby, Michael H. Cummings, Zoe L. Saynor, Anthony I. Shepherd, Janis K. Shute, Samuel R. Wallbanks
Publikováno v:
Causer, A J, Shute, J, Cummings, M H, Shepherd, A, Wallbanks, S R, Allenby, M I, Arregui-Fresneda, I, Bright, V, Carroll, M P, Connett, G, Daniels, T, Meredith, T & Saynor, Z 2020, ' The implications of dysglycaemia on aerobic exercise and ventilatory function in cystic fibrosis ', Journal of Cystic Fibrosis, vol. 19, no. 3, pp. 427-433 . https://doi.org/10.1016/j.jcf.2019.09.014
Background: The development of cystic fibrosis (CF)-related diabetes (CFRD) in paediatric groups is associated with a reduced aerobic fitness. However, this has yet to be investigated in adults with more severe lung disease.Methods: Cardiopulmonary e
Autor:
Janis K. Shute, Maha Khalaf, Zoe L. Saynor, Stephen J. Bailey, Adam J. Causer, Michael H. Cummings, Emily Klein Rot, Jim T. Smith, Anthony I. Shepherd, Kimberly Brand
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 23, Pp n/a-n/a (2021)
Micro‐ and macrovascular endothelial dysfunction in response to shear stress has been observed in cystic fibrosis (CF), and has been associated with inflammation and oxidative stress. We tested the hypothesis that the cystic fibrosis transmembrane
Autor:
Janis K. Shute
Publikováno v:
Minerva medica. 113(1)
Biomarkers may be diagnostic of asthma, they may predict or reflect response to therapy or they may identify patients at risk of asthma exacerbation. A biomarker is most often measured in biologic fluids that are sampled using relatively non-invasive
Autor:
Christopher Corrigan, Alan L. James, Sajeel A. Shah, Yanira Riffo-Vasquez, John G. Elliot, Clive P. Page, Zainab Mohamed, Simon C. Pitchford, Varsha Kanabar, Janis K. Shute, Simon J. Cleary
Publikováno v:
Shah, S A, Kanabar, V, Riffo-Vasquez, Y, Mohamed, Z, Cleary, S J, Corrigan, C, James, A L, Elliott, J G, Shute, J K, Page, C P & Pitchford, S C 2021, ' Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3 ', American Journal of Respiratory Cell and Molecular Biology, vol. 64, no. 5, pp. 557–568 . https://doi.org/10.1165/rcmb.2020-0425OC
American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology
Platelet activation and pulmonary recruitment occur in patients with asthma and in animal models of allergic asthma, in which leukocyte infiltration, airway remodeling, and hyperresponsiveness are suppressed by experimental platelet depletion. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec64117fa68f54360c906d25df93a078
https://kclpure.kcl.ac.uk/ws/files/155174783/rcmb.2020_0425oc.pdf
https://kclpure.kcl.ac.uk/ws/files/155174783/rcmb.2020_0425oc.pdf
Autor:
Alicia Vilaseca, Mary P. Carroll, Antonio Artigas, Rabab S. Mahrous, Marta Camprubí-Rimblas, Hwan-Jin Yoon, Christopher Hillman, Lex van Loon, Janis K. Shute, Barry Dixon, Miles W. Carroll, Gilberto De Nucci, Tarek I. Ismail, Mohamed Badr, Dave Singh, Frank van Haren, John G. Laffey, Anusha Belani, Carlos Eduardo Sverdloff, Clive P. Page, Tom Wilkinson, Sabrina Staas, Khine Sann, Thomas Smoot, David W. Cosgrave, Caitlin Sas, Alice Richardson, Ruben Barbera, Roger J Smith
Publikováno v:
British Journal of Clinical Pharmacology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Aims: inhaled nebulised unfractionated heparin (UFH) has a strong scientific and biological rationale that warrants urgent investigation of its therapeutic potential in patients with COVID‐19. UFH has antiviral effects and prevents the SARS‐CoV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a464917b105c48466aae2addb3270425
https://eprints.soton.ac.uk/446588/
https://eprints.soton.ac.uk/446588/
Autor:
Dave Singh, John G. Laffey, Jin Yoon, Ruben Barbera, Clive P. Page, Lex van Loon, Antonio Artigas, Carlos Eduardo Sverdloff, Anusha Belani, Alicia Vilaseca, Sabrina Staas, Mary P. Carroll, Marta Camprubí-Rimblas, Khine Sann, Tom Wilkinson, Frank van Haren, Caitlin Sas, Gilberto De Nucci, Tarek I. Ismail, Janis K. Shute, Miles W. Carroll, Barry Dixon, Christopher Hillman, Roger Smith, Thomas Smoot, Mohamed Badr, Rabab S. Mahrous, Alice Richardson, David Cosgrave
Introduction Inhaled nebulised unfractionated heparin (UFH) has a strong scientific and biological rationale and warrants urgent investigation of its therapeutic potential for COVID-19. UFH has antiviral effects and prevents the SARS-CoV-2 virus’ e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58e6ce3b3acc57493054b76a37262088
https://doi.org/10.22541/au.160702908.84293841/v1
https://doi.org/10.22541/au.160702908.84293841/v1