Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Janis Gonzalez-Martinez"'
Comparative Analysis of Gene Expression Patterns for Oral Epithelial Cell Functions in Periodontitis
Autor:
Octavio A. Gonzalez, Sreenatha Kirakodu, Linh M. Nguyen, Luis Orraca, Michael J. Novak, Janis Gonzalez-Martinez, Jeffrey L. Ebersole
Publikováno v:
Frontiers in Oral Health, Vol 3 (2022)
The structure and function of epithelial cells are critical for the construction and maintenance of intact epithelial surfaces throughout the body. Beyond the mechanical barrier functions, epithelial cells have been identified as active participants
Externí odkaz:
https://doaj.org/article/93da86d21d604aef9de58fcb9d2920de
Autor:
Sahana Kuthyar, Karli Watson, Shi Huang, Lauren J N Brent, Michael Platt, Julie Horvath, Janis Gonzalez-Martinez, Melween Martínez, Filipa Godoy-Vitorino, Rob Knight, Maria Gloria Dominguez-Bello, Katherine R Amato
Publikováno v:
FEMS microbiology ecology. 98(10)
Gut microbial communities are shaped by a myriad of extrinsic factors, including diet and the environment. Although distinct human populations consistently exhibit different gut microbiome compositions, variation in diet and environmental factors are
Autor:
Jeffrey L. Ebersole, Armando Burgos, M. J. Novak, Sreenatha Kirakodu, Janis Gonzalez-Martinez, A.J. Stormberg, Octavio A. Gonzalez, Luis Orraca
Publikováno v:
Immunobiology. 224:196-206
Host-derived pattern recognition receptors (PRRs) are necessary for effective innate immune engagement of pathogens that express microbial-associated molecular patterns (MAMP) ligands for these PRRs. This study used a nonhuman primate model to evalua
Autor:
Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Elliot Neumann, Luis Orraca, Janis Gonzalez Martinez, Octavio A. Gonzalez
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Apoptosis and autophagy are described as important regulators of cellular functions, particularly related to nutritional stress that could be induced by infection and inflammation. As such, recent results support an important role for each of these c
Autor:
M. J. Novak, Octavio A. Gonzalez, Sreenatha Kirakodu, Dolph Dawson, Armando Burgos, Arnold J. Stromberg, Luis Orraca, Janis Gonzalez-Martinez, Jeffrey L. Ebersole
Publikováno v:
Journal of periodontal researchREFERENCES. 56(1)
OBJECTIVE We hypothesized that autophagy-related genes will be differentially expressed in periodontitis, suggesting an impaired gingival autophagic response associated with disease. BACKGROUND Autophagy is a cellular physiologic mechanism to maintai
Autor:
Octavio A. Gonzalez, Terry B. Kensler, Jeffrey L. Ebersole, Elisabeth Maldonado, Luis Orraca, Janis Gonzalez-Martinez
Publikováno v:
Journal of Periodontal Research. 54:134-142
Objective and background The expression of periodontitis, including age of onset, extent, and severity is considered to represent an interaction of the individual's oral microbiome and host response to the microbial challenge that is modified by both
Autor:
M. J. Novak, Sreenatha Kirakodu, Armando Burgos, L. Orraca, Octavio A. Gonzalez, A. J. Stromberg, Jeffrey L. Ebersole, Janis Gonzalez-Martinez
Publikováno v:
Immunobiology. 223:279-287
Host-bacterial interactions at mucosal surfaces require recognition of the bacteria by host cells enabling targeted responses to maintain tissue homeostasis. It is now well recognized that an array of host-derived pattern recognition receptors (PRRs)
Autor:
Jeffrey L. Ebersole, Octavio A. Gonzalez, Sreenatha Kirakodu, Janis Gonzalez Martinez, Jin Chen
This investigation compared the microbiomes colonizing teeth during the initiation, progression, and resolution of periodontitis in nonhuman primates (Macaca mulatta) at different ages. Subgingival plaque samples were collected at baseline; 0.5, 1, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060ba8e04506d8bece436e9b1b332458
https://europepmc.org/articles/PMC6529664/
https://europepmc.org/articles/PMC6529664/
Autor:
Sreenatha Kirakodu, John Ferrin, Ahmad Al-Attar, Mohanad Al-Sabbagh, David Jensen, Armando Burgos, Arnold J. Stromberg, Dolph Dawson, Rebecca Peyyala, Octavio A. Gonzalez, M. John Novak, Jeffrey L. Ebersole, Janis Gonzalez-Martinez, Luis Orraca
Background Neuropeptides (NPs) are innate pivotal regulators of the immunoinflammatory response. Nevertheless, their role in the pathogenesis of periodontal disease remains unknown. Changes in gene expression of 10 NPs and 16 NP receptors (NPRs) coin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9493a5ec7c484c344003e05ac02e9840
https://europepmc.org/articles/PMC6322539/
https://europepmc.org/articles/PMC6322539/
Autor:
Octavio A. Gonzalez, Shu Shen, M. J. Novak, Sreenatha Kirakodu, C.R. Exposto, J. L. Ebersole, Janis Gonzalez-Martinez, Luis Orraca, Arnold J. Stromberg
Publikováno v:
Molecular Oral Microbiology. 31:18-32
The molecular changes underlying the higher risk of chronic inflammatory disorders during aging remain incompletely understood. Molecular variations in the innate immune response related to recognition and interaction with microbes at mucosal surface