Výsledky vyhledávání - "Janis Casper"

Endothelial‐to‐mesenchymal transition shapes the atherosclerotic plaque and modulates macrophage function

Autor: Sascha David, Hermann Haller, Alexandra Helmke, Elisabeth M Zeisberg, Johannes Nordlohne, Janis Casper, Sibylle von Vietinghoff

Publikováno v: The FASEB Journal. 33:2278-2289

Endothelial cells can acquire a mesenchymal phenotype upon irritation [endothelial-to-mesenchymal transition (EndMT)]. Macrophages accumulate in the atherosclerotic plaque. This study addressed whether macrophages modulate EndMT and delineated a reci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320e7b68c8a4a4bd6d0a712a123bc77a
https://doi.org/10.1096/fj.201801238r

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Protein kinase C beta deficiency increases glucose-mediated peritoneal damage via M1 macrophage polarization and up-regulation of mesothelial protein kinase C alpha

Autor: Song Rong, Hermann Haller, Alexandra Helmke, Le Wang, Marcus Hiss, Michael S. Balzer, Nelli Shushakova, Lei Dong, Yulia Kiyan, Martina Ackermann, Sibylle von Vietinghoff, Janis Casper, Kai Timrott

Publikováno v: Nephrology Dialysis Transplantation. 34:947-960

Background Peritoneal membrane (PM) damage during peritoneal dialysis (PD) is mediated largely by high glucose (HG)-induced pro-inflammatory and neo-angiogenic processes, resulting in PM fibrosis and ultrafiltration failure. We recently demonstrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f347ca09ded70cf184f63e0a497826e5
https://doi.org/10.1093/ndt/gfy282

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Renal transplant recipients receiving loop diuretic therapy have increased urinary tract infection rate and altered medullary macrophage polarization marker expression

Autor: Gunilla Einecke, Hermann Haller, Jessica Schmitz, Bernhard M W Schmidt, Abedalrazag Khalifa, Jan Hinrich Bräsen, Janis Casper, Sibylle von Vietinghoff

Publikováno v: Kidney international. 94(5)

Loop diuretics deplete the renal cortico-medullary salt gradient that has recently been established as a major modulator of immune responses. Renal transplant recipients suffer from a markedly increased rate of urinary tract infections (UTIs). Whethe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0c7e6bff3ebb3eb40264264666e5a3
https://pubmed.ncbi.nlm.nih.gov/31634062

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