Výsledky vyhledávání - "Janis Ancans"

Efficacy of Ozonation Treatments of Smoked Fish for Reducing Its Benzo[a]pyrene Concentration and Toxicity

Autor: Vadims Bartkevics, Janis Ancans, Irina Rozentale, Arturs Viksna, Elena Bartkiene

Publikováno v: Journal of Food Protection. 79:2167-2173

Ozone is widely used in food processing, for example, to decompose mycotoxins or pesticide residues, to extend the shelf life of products, and for sanitation. The objective of this study was to assess the possibility of expanding the application of o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b11408af171f0d453edb27ef548109
https://doi.org/10.4315/0362-028x.jfp-16-133

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Manufacturing, characterization and control of cell-based medicinal products: challenging paradigms toward commercial use

Autor: Metoda Lipnik-Stangelj, Patrick Celis, Ilona Reischl, Paula Salmikangas, Jean-Hugues Trouvin, Guido Pante, Janis Ancans, Sol Ruiz, Egbert Flory, Asterios S. Tsiftsoglou, Margarida Menezes-Ferreira, Jan Kyselovic, John Joseph Borg, Marcos Timon, Christian Schneider, Dariusz Sladowski

Publikováno v: Regenerative Medicine. 10:65-78

During the past decade, a large number of cell-based medicinal products have been tested in clinical trials for the treatment of various diseases and tissue defects. However, licensed products and those approaching marketing authorization are still f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a7eca7de7948eea46b63af7b465681
https://doi.org/10.2217/rme.14.65

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Characterization of human skin-derived mesenchymal stem cell proliferation rate in different growth conditions

Autor: Una Riekstina, Indrikis Muiznieks, Janis Ancans, Ruta Muceniece, Inese Cakstina

Publikováno v: Cytotechnology. 58:153-162

This study investigated conditions for optimal in vitro propagation of human skin-derived mesenchymal stem cells (S-MSC). Forty primary skin-derived precursor cell (SKP) cultures were established from both male and female donors (age 29–65 years) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcac0709ade7d3a34ad958b787e4463
https://doi.org/10.1007/s10616-009-9183-2

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P-Locus Is a Target for the Melanogenic Effects of MC-1R Signaling

Autor: Martin J. Hoogduijn, Anthony J. Thody, Janis Ancans, Niamh Flanagan

Publikováno v: Annals of the New York Academy of Sciences. 994:373-377

Melanocortin receptor type 1 (MC-1R) is an important control point for ultraviolet ray (UVR)-induced tanning response in the skin. In this study, we show that p-locus is a downstream target for MC-1R signaling. The expression of p-locus was up-regula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12299fd4c51b56d47a0bab62a4c2297f
https://doi.org/10.1111/j.1749-6632.2003.tb03202.x

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Ligand-Dependent Activation of the Melanocortin 5 Receptor: cAMP Production and Ryanodine Receptor-Dependent Elevations of [Ca2+]i

Autor: Nico P.M. Smit, S. McGurk, Peter H. Nibbering, Janis Ancans, Martin J. Hoogduijn, Anthony J. Thody, A. van der Laarse

Publikováno v: Biochemical and Biophysical Research Communications, 290(2), 844-850. Academic Press

The melanocortins are involved in the regulation of various cognitive and physiological processes such as learning, feeding, immune suppression, pigmentation, and sebum production. Five melanocortin receptors have been identified, of which the melano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d1a874097891b2cbdddcf28f99ec18
https://doi.org/10.1006/bbrc.2001.6283

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Melanin-concentrating hormone and its receptor are expressed and functional in human skin

Autor: Itaru Suzuki, Siân E. Estdale, Janis Ancans, Anthony J. Thody, Martin J. Hoogduijn

Publikováno v: Biochemical and Biophysical Research Communications, 296(3), 698-701. Academic Press

In this study, we have demonstrated the presence of melanin-concentrating hormone (MCH) and melanin-concentrating hormone receptor (MCHR1) transcripts in human skin. Sequence analysis confirmed that the transcripts of both genes were identical to tho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9632843b89e2a25a17fe2d00818ec8
https://doi.org/10.1016/s0006-291x(02)00932-4

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Melanosomal pH controls rate of melanogenesis, eumelanin/phaeomelanin ratio and melanosome maturation in melanocytes and melanoma cells

Autor: Kazumasa Wakamatsu, Nico P.M. Smit, Anthony J. Thody, Janis Ancans, Martin J. Hoogduijn, Desmond J. Tobin

Publikováno v: Experimental Cell Research, 268(1), 26-35. Elsevier Inc.

The skin pigment melanin is produced in melanocytes in highly specialized organelles known as melanosomes. Melanosomes are related to the organelles of the endosomal/lysosomal pathway and can have a low internal pH. In the present study we have shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3374b6bb1661eb029360c86b01ad6bfc
https://doi.org/10.1006/excr.2001.5251

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Activation of melanogenesis by vacuolar type H+ -ATPase inhibitors in amelanotic, tyrosinase positive human and mouse melanoma cells

Autor: Janis Ancans, Anthony J. Thody

Publikováno v: FEBS Letters. 478:57-60

In this study, we describe the activation of melanogenesis by selective vacuolar type H(+)-ATPase inhibitors (bafilomycin A1 and concanamycin A) in amelanotic human and mouse melanoma cells which express tyrosinase but show no melanogenesis. Addition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec67badbc18ec8d98ac4c2be3f172549
https://doi.org/10.1016/s0014-5793(00)01795-6

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