Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Janire, Mingo"'
Autor:
Caroline E. Nunes-Xavier, Maite Emaldi, Janire Mingo, Tove Øyjord, Gunhild M. Mælandsmo, Øystein Fodstad, Peio Errarte, Gorka Larrinaga, Roberto Llarena, José I. López, Rafael Pulido
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Renal cancer cells constitute a paradigm of tumor cells with a glycolytic reprogramming which drives metabolic alterations favouring cell survival and transformation. We studied the expression and activity of pyruvate dehydrogenase kinases (
Externí odkaz:
https://doaj.org/article/3725a04e6a124d489f00f2b0b256bf47
Autor:
Caroline E. Nunes‑Xavier, Maite Emaldi, Janire Mingo, Tove Øyjord, Gunhild M. Mælandsmo, Øystein Fodstad, Peio Errarte, Gorka Larrinaga, Roberto Llarena, José I. López, Rafael Pulido
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/5dabc4b78ce44a08ae82cc15d0f76d15
Autor:
Caroline E. Nunes-Xavier, Janire Mingo, Maite Emaldi, Karine Flem-Karlsen, Gunhild M. Mælandsmo, Øystein Fodstad, Roberto Llarena, José I. López, Rafael Pulido
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundPyruvate dehydrogenase (PDH) complex converts pyruvate into acetyl-CoA by pyruvate decarboxylation, which drives energy metabolism during cell growth, including prostate cancer (PCa) cell growth. The major catalytic subunit of PDH, PDHA1, i
Externí odkaz:
https://doaj.org/article/060cb01a32194d9ab44dea2f0e95b000
Autor:
Janire Mingo, Asier Erramuzpe, Sandra Luna, Olaia Aurtenetxe, Laura Amo, Ibai Diez, Jan T G Schepens, Wiljan J A J Hendriks, Jesús M Cortés, Rafael Pulido
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160972 (2016)
Site-directed mutagenesis (SDM) is a powerful tool to create defined collections of protein variants for experimental and clinical purposes, but effectiveness is compromised when a large number of mutations is required. We present here a one-tube-onl
Externí odkaz:
https://doaj.org/article/04d9e549bcc447738dfc7af4f1ca7945
Autor:
Víctor J. Cid, Julia María Coronas-Serna, Marta Valenti, Elba del Val, Teresa Fernández-Acero, Isabel Rodríguez-Escudero, Rafael Pulido, Janire Mingo, María Molina, Leire Torices, Sandra Luna
Publikováno v:
International Microbiology. 23:75-87
The yeast Saccharomyces cerevisiae is a model organism that has been thoroughly exploited to understand the universal mechanisms that govern signaling pathways. Due to its ease of manipulation, humanized yeast models that successfully reproduce the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0b24c93bd8e82d34cd0909ab185fe8
https://doi.org/10.1007/s10123-019-00082-4
https://doi.org/10.1007/s10123-019-00082-4
Autor:
Rafael Pulido, Pablo Ruiz-Ibarlucea, Caroline E. Nunes-Xavier, Laura Amo, María Molina, Janire Mingo, Maria I. Tejada, José I. López, Leire Torices, Víctor J. Cid, Sandra Luna, Isabel Rodríguez-Escudero, Asier Erramuzpe, Jesus M. Cortes
Publikováno v:
Human mutationREFERENCES. 42(5)
The PTEN tumor suppressor gene is mutated with high incidence in tumors and in the germline of patients with cancer predisposition or with macrocephaly associated to autism. PTEN nonsense mutations generating premature termination codons (PTC) and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c635ac8507729d8f48999fbf2306d3
https://pubmed.ncbi.nlm.nih.gov/33600059
https://pubmed.ncbi.nlm.nih.gov/33600059
Autor:
Ayman Gaafar, José I. López, Janire Mingo, Leire Torices, Caroline E. Nunes-Xavier, Sandra Luna, Javier C. Angulo, Rafael Pulido
Publikováno v:
Cold Spring Harb Perspect Med
PTEN is a major tumor-suppressor protein whose expression and biological activity are frequently diminished in sporadic or inherited cancers. PTEN gene deletion or loss-of-function mutations favor tumor cell growth and are commonly found in clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1583ccc2961a36e7ee810f84dd5150b
https://europepmc.org/articles/PMC6886455/
https://europepmc.org/articles/PMC6886455/
Autor:
Roberto Llarena, Janire Mingo, Rafael Pulido, Leire Torices, Isabel Guerra, Rebeca Ruiz, Javier C. Angulo, Sandra Luna, José I. López, Caroline E. Nunes-Xavier, Lorena Mosteiro, Ayman Gaafar
Publikováno v:
NPJ Precision Oncology
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
npj Precision Oncology, Vol 3, Iss 1, Pp 1-9 (2019)
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
npj Precision Oncology, Vol 3, Iss 1, Pp 1-9 (2019)
Anti-PTEN monoclonal antibodies (mAb) are arising as important tools for immunohistochemistry (IHC) and protein quantification routine analysis in clinical oncology. Although an effort has been made to document the reliability of tumor tissue section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b3735b22d8cf535d3f591efb4dcfa
http://europepmc.org/articles/PMC6465295
http://europepmc.org/articles/PMC6465295
Autor:
Nashaat Z. Gerges, Erik B. Faber, Inmaculada Pereda-Pérez, Mark R. Spaller, Randy A. Hall, Jose Viña, Liping Mou, Lara Ordóñez-Gutiérrez, José A. Esteban, Cristina Sánchez-Puelles, Rafael Pulido, Andrew K Chan, Tina Wahle, Manuel Serrano, Janire Mingo, Heidi M Chapman, Francisco Wandosell, Ana Ortega-Molina, Shira Knafo, Kanwardeep Kaleka, Jonathan E. Draffin, Laura Lozano-Montes, Igotz Delgado, Edvin Klosi, César Venero, Ernest Palomer, Carlos G. Dotti
Publikováno v:
NATURE NEUROSCIENCE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Dyshomeostasis of amyloid-β peptide (Aβ) is responsible for synaptic malfunctions leading to cognitive deficits ranging from mild impairment to full-blown dementia in Alzheimer's disease. Aβ appears to skew synaptic plasticity events toward depres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5f5cabb78039676dfeceea2eba5fb1
https://doi.org/10.1038/nn.4225
https://doi.org/10.1038/nn.4225
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1866(1)
Prostate cancer (PCa) is the most frequent malignancy in the male population of Western countries. Although earlier detection and more active surveillance have improved survival, it is still a challenge how to treat advanced cases. Since androgen rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f244509a6caa44c32d7c16313ce57369
https://pubmed.ncbi.nlm.nih.gov/30401533
https://pubmed.ncbi.nlm.nih.gov/30401533