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Autor:
Alexander M.M. Eggermont, M. Thomas, Janine Wechlser, Nyam Kamsu-Kom, Christine Mateus, Emilie Routier, Ludovic Lacroix, H. Cazenave, Séverine Roy, Lise Boussemart, Isabelle Girault, Caroline Robert, Stéphan Vagner, Gorana Tomasic, Michel Favre
Publikováno v:
Cancer Research. 74:934-934
INTRODUCTION : BRAF inhibitors (BRAFI) are affective anti-melanoma agents in V600BRAF mutant melanoma but have one major adverse event, the paradoxical activation of MAPK pathway in WT BRAF cells, which favors the emergence of benign, borderline and