Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Janine Tadje"'
Autor:
Annegret Gerber, Vera Preller, Sabine Wrenger, Janine Tadje, Didier Marguet, Klaus Neubert, Uwe Lendeckel, Burkhart Schraven, Siegfried Ansorge, Jürgen Faust, Mauro Togni, Stefan Brocke, Christoph Röcken, Dirk Reinhold, Roland Martin
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 178 (7), pp.4632-40
Journal of Immunology, 2007, 178 (7), pp.4632-40
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 178 (7), pp.4632-40
Journal of Immunology, 2007, 178 (7), pp.4632-40
The T cell marker CD26/dipeptidyl peptidase (DP) IV is associated with an effector phenotype and markedly elevated in the human CNS disorder multiple sclerosis. However, little is known about the in vivo role of CD26/DP IV in health and disease, and
Autor:
Siegfried Ansorge, Anke Heimburg, Klaus Neubert, Carmen Wolke, Jürgen Faust, Michael Täger, Ute Bank, Gudrun Koch, Martin Helmuth, Uwe Lendeckel, Petra Fuchs, Janine Tadje, Anja Thielitz, Dirk Reinhold
Publikováno v:
Clinical chemistry and laboratory medicine. 47(3)
Background: In the past, different research groups could show that treatment of immune cells with inhibitors of post-proline splitting dipeptidyl aminopeptidases leads to functional changes in the immune system consistent with immunosuppression. This
Autor:
Dirk Reinhold, Carmen Wolke, Uwe Lendeckel, Michael Täger, Michael Vieth, Martin Helmuth, Alicja Bukowska, Peter Malfertheiner, Michael Naumann, Ann Shakespeare, Janine Tadje, Siegfried Ansorge, A. Ittenson, Ute Bank
Publikováno v:
International Journal of Molecular Medicine.
Inhibitors of alanyl-aminopeptidase e.g. phebestin increase the expression of transforming growth factor (TGF)-Bl in mononuclear cells. We investigated whether phebestin also produced this effect in CD4 + CD25 + T-cells and whether phebestin-treated
Autor:
Ute, Bank, Janine, Tadje, Michael, Täger, Carmen, Wolke, Alicja, Bukowska, Annelore, Ittenson, Dirk, Reinhold, Martin, Helmuth, Siegfried, Ansorge, Ann, Shakespeare, Michael, Vieth, Peter, Malfertheiner, Michael, Naumann, Uwe, Lendeckel
Publikováno v:
International journal of molecular medicine. 20(4)
Inhibitors of alanyl-aminopeptidase e.g. phebestin increase the expression of transforming growth factor (TGF)-beta1 in mononuclear cells. We investigated whether phebestin also produced this effect in CD4+CD25+ T-cells and whether phebestin-treated
Autor:
Siegfried Ansorge, A. Ittenson, Dirk Reinhold, Michael Täger, Janine Tadje, Anke Wischeropp, Martin Helmuth, Ute Bank, Carmen Wolke, Sofia Stefin, Uwe Lendeckel
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387290584
In summary these results strongly support the idea that AAPs and DPIV represent a promising target complex for the pharmacological therapy of T cell-mediated diseases by preserving and enhancing endogenous immunosuppressive mechanisms. Whereas inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35b612c77fcad0cdfacc40c17ada0226
https://doi.org/10.1007/0-387-32824-6_15
https://doi.org/10.1007/0-387-32824-6_15
Autor:
Ute, Bank, Janine, Tadje, Martin, Helmuth, Sofia, Stefin, Michael, Täger, Carmen, Wolke, Anke, Wischeropp, Annelore, Ittenson, Dirk, Reinhold, Siegfried, Ansorge, Uwe, Lendeckel
Publikováno v:
Advances in experimental medicine and biology. 575
Autor:
Carmen Wolke, Siegfried Ansorge, Uwe Lendeckel, A. Ittenson, Alicja Bukowska, Ute Bank, Michael Täger, Janine Tadje
Publikováno v:
International journal of molecular medicine. 17(2)
The human CD30-positive anaplastic large (T-) cell lymphoma cell line, KARPAS-299 (DSM ACC31), was established from blast cells in the peripheral blood from a case of non-Hodgkin lymphoma in 1988. We describe the mRNA and surface expression in KARPAS
Autor:
Thilo Kähne, Klaus Neubert, Siegfried Ansorge, A. Ittenson, Carmen Wolke, Jürgen Faust, Janine Tadje, Alicja Bukowska, Uwe Lendeckel, Marco Arndt, Dirk Reinhold
Publikováno v:
Dipeptidyl Aminopeptidases in Health and Disease ISBN: 0306477173
Inhibitors of the enzymatic activity of alanyl-aminopeptidases severely affect growth and typical functions of human peripheral T cells both in vitro and in vivo. The most prominent changes observed include the activation of cellular signal transduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a39ca4fb2e91106e760b9c11aa46f866
https://doi.org/10.1007/0-306-47920-6_16
https://doi.org/10.1007/0-306-47920-6_16
Autor:
Uwe, Lendeckel, Marco, Arndt, Alicja, Bukowska, Janine, Tadje, Carmen, Wolke, Thilo, Kähne, Klaus, Neubert, Jürgen, Faust, Annelore, Ittenson, Siegfried, Ansorge, Dirk, Reinhold
Publikováno v:
Advances in experimental medicine and biology. 524
Inhibitors of the enzymatic activity of alanyl-aminopeptidases severely affect growth and typical functions of human peripheral T cells both in vitro and in vivo. The most prominent changes observed include the activation of cellular signal transduct
Autor:
Uwe Lendeckel, Jürgen Faust, Klaus Neubert, Alicja Bukowska, Janine Tadje, Marco Arndt, Carmen Wolke, Thilo Kähne, Yuichi Hashimoto, Jaqueline Bartsch
Publikováno v:
Biological Chemistry. 384
Aminopeptidase inhibitors strongly affect the proliferation and function of immune cells in man and animals and are promising agents for the pharmacological treatment of inflammatory or autoimmune diseases. Membrane alanyl-aminopeptidase (mAAP) has b