Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Janine Regneri"'
Autor:
Yuan Lu, Mikki Boswell, William Boswell, Susanne Kneitz, Barbara Klotz, Markita Savage, Raquel Salinas, Rebecca Marks, Janine Regneri, John Postlethwait, Wesley C Warren, Manfred Schartl, Ronald Walter
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007875 (2018)
Understanding the genetic mechanisms underlying segregation of phenotypic variation through successive generations is important for understanding physiological changes and disease risk. Tracing the etiology of variation in gene expression enables ide
Externí odkaz:
https://doaj.org/article/0df5abbca03940fe8196b5f55ea64255
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59442 (2013)
Bone Morphogenetic Proteins (BMPs) are important growth factors that regulate many cellular processes. During embryogenesis they act as morphogens and play a critical role during organ development. They influence cell fates via concentration-gradient
Externí odkaz:
https://doaj.org/article/66308907791c45efa1632f6755026412
Autor:
Susanne Kneitz, Verena A. Kottler, Janine Regneri, Barbara Klotz, Katja Maurus, Michael Hausmann, Yuan Lu, Ronald B. Walter, Amaury Herpin, Brigitta Wilde, Manfred Schartl, Martina Regensburger, Ralph Götz
Publikováno v:
Pigment Cell and Melanoma Research
Pigment Cell and Melanoma Research, 2019, 32 (2), pp.248-258. ⟨10.1111/pcmr.12729⟩
Pigment Cell and Melanoma Research, 2019, 32 (2), pp.248-258. ⟨10.1111/pcmr.12729⟩
In humans, the CDKN2A locus encodes two transcripts, INK4A and ARF. Inactivation of either one by mutations or epigenetic changes is a frequent signature of malignant melanoma and one of the most relevant entry points for melanomagenesis. To analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb8c1f47a24122e5f8a49079a476894
https://doi.org/10.1111/pcmr.12729
https://doi.org/10.1111/pcmr.12729
Autor:
Janine Regneri, Barbara Klotz, Amaury Herpin, Brigitta Wilde, Hisashi Hashimoto, Manfred Schartl
Publikováno v:
Pigment Cell & Melanoma Research. 30:e27-e137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18248beb6db265763b9451fa82514a1
https://doi.org/10.1111/pcmr.12622
https://doi.org/10.1111/pcmr.12622
Autor:
William T. Boswell, Susanne Kneitz, Yuan Lu, Manfred Schartl, Markita G. Savage, Ronald B. Walter, Janine Regneri, Barbara Klotz, Cristina Mendoza, Wesley C. Warren, John H. Postlethwait, Mikki Boswell
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Cell culture and protein target-based compound screening strategies, though broadly utilized in selecting candidate compounds, often fail to eliminate candidate compounds with non-target effects and/or safety concerns until late in the drug developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc8c1e51ea5ce396ebd8073dacc0d12
https://doi.org/10.1038/s41598-018-36656-x
https://doi.org/10.1038/s41598-018-36656-x
Autor:
William T. Boswell, Rebecca Marks, Susanne Kneitz, Wesley C. Warren, John H. Postlethwait, Markita G. Savage, Janine Regneri, Barbara Klotz, Mikki Boswell, Raquel Salinas, Manfred Schartl, Ronald B. Walter, Yuan Lu
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007875 (2018)
PLoS Genetics
PLoS Genetics
Understanding the genetic mechanisms underlying segregation of phenotypic variation through successive generations is important for understanding physiological changes and disease risk. Tracing the etiology of variation in gene expression enables ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ba4158ded4b1d4617d190b40498781
https://doaj.org/article/0df5abbca03940fe8196b5f55ea64255
https://doaj.org/article/0df5abbca03940fe8196b5f55ea64255
Autor:
Yuan Lu, Manfred Schartl, Janine Regneri, Barbara Klotz, Susanne Kneitz, Angel Amores, Ronald B. Walter, William T. Boswell, Markita G. Savage, Wesley C. Warren, John H. Postlethwait, Mikki Boswell, Michael Hausmann
To functionally assess the oncogene xmrk co-expressed genes, and compare the functional pathways of these genes to pathways represented in the human melanoma subgroups that were characterized by high and low pigmentation function, we performed gene e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a6f85d965c811a8e0c27c23b56a571
https://europepmc.org/articles/PMC6013346/
https://europepmc.org/articles/PMC6013346/
Autor:
Susanne Kneitz, Michael Hausmann, William T. Boswell, Manfred Schartl, Markita G. Savage, Yuan Lu, Wesley C. Warren, John H. Postlethwait, Janine Regneri, Barbara Klotz, Ronald B. Walter, Mikki Boswell, Angel Amores
Publikováno v:
Molecular carcinogenesis. 56(8)
Development of spontaneous melanoma in Xiphophorus interspecies backcross hybrid progeny, (X. hellerii × [X. maculatus Jp 163 A × X. hellerii]) is due to Mendelian segregation of a oncogene (xmrk) and a molecularly uncharacterized locus, called R(D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05125ddbba6d33f056af3c99f46654fe
https://pubmed.ncbi.nlm.nih.gov/28345808
https://pubmed.ncbi.nlm.nih.gov/28345808
Zebrafish and medaka that develop tumors have become valuable tools for experimental cancer research. With the advent of microarrays and new sequencing technologies it has become feasible to perform whole genome, exome, and transcriptome analyses in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f51e685f8c20bc79692dc118f68a6824
https://doi.org/10.1016/bs.adgen.2016.04.001
https://doi.org/10.1016/bs.adgen.2016.04.001
Publikováno v:
Comparative biochemistry and physiology. Toxicologypharmacology : CBP. 178
Melanoma development in interspecific hybrids of Xiphophorus is induced by the overexpression of the mutationally activated receptor tyrosine kinase Xmrk in pigment cells. Based on the melanocyte specificity of the transcriptional upregulation, a pig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1362b61073a0b3ae97d33d765c0543
https://pubmed.ncbi.nlm.nih.gov/26348392
https://pubmed.ncbi.nlm.nih.gov/26348392