Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Janine Murr"'
Autor:
Alexandra Nguyen, Al-Hassan M. Mustafa, Alessa K. Leydecker, Melisa Halilovic, Janine Murr, Falk Butter, Oliver H. Krämer
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract As a major source of cellular serine and threonine phosphatase activity, protein phosphatase-2A (PP2A) modulates signaling pathways in health and disease. PP2A complexes consist of catalytic, scaffolding, and B-type subunits. Seventeen PP2A
Externí odkaz:
https://doaj.org/article/9e6174433b8147c5a564a52252e4791f
Autor:
Felix Orben, Katharina Lankes, Christian Schneeweis, Zonera Hassan, Hannah Jakubowsky, Lukas Krauß, Fabio Boniolo, Carolin Schneider, Arlett Schäfer, Janine Murr, Christoph Schlag, Bo Kong, Rupert Öllinger, Chengdong Wang, Georg Beyer, Ujjwal M. Mahajan, Yonggan Xue, Julia Mayerle, Roland M. Schmid, Bernhard Kuster, Roland Rad, Christian J. Braun, Matthias Wirth, Maximilian Reichert, Dieter Saur, Günter Schneider
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Systemic therapies for pancreatic ductal adenocarcinoma (PDAC) remain unsatisfactory. Clinical prognosis is particularly poor for tumor subtypes with activating aberrations in the MYC pathway, creating an urgent need for novel therapeutic targets. To
Externí odkaz:
https://doaj.org/article/eb693ba667cc4d5dae97e9b398a9f104
Publikováno v:
Cells, Vol 10, Iss 10, p 2520 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease with a dismal prognosis. Here, we show how an inhibition of de novo dNTP synthesis by the ribonucleotide reductase (RNR) inhibitor hydroxyurea and an inhibition of epigenetic modi
Externí odkaz:
https://doaj.org/article/9619372e9a2c4dd6b8632439e2a4713f
Autor:
Felix Orben, Katharina Lankes, Christian Schneeweis, Zonera Hassan, Hannah Jakubowsky, Lukas Krauß, Fabio Boniolo, Carolin Schneider, Arlett Schäfer, Janine Murr, Christoph Schlag, Bo Kong, Rupert Öllinger, Chengdong Wang, Georg Beyer, Ujjwal M. Mahajan, Yonggan Xue, Julia Mayerle, Roland M. Schmid, Bernhard Kuster, Roland Rad, Christian J. Braun, Matthias Wirth, Maximilian Reichert, Dieter Saur, Günter Schneider
Publikováno v:
JCI insight. 7(10)
Systemic therapies for pancreatic ductal adenocarcinoma (PDAC) remain unsatisfactory. Clinical prognosis is particularly poor for tumor subtypes with activating aberrations in the MYC pathway, creating an urgent need for novel therapeutic targets. To
Autor:
Suzanne Cole, Janine Murray, Catherine Simpson, Remi Okoye, Kerry Tyson, Meryn Griffiths, Dominique Baeten, Stevan Shaw, Asher Maroof
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for inducing IL-17 production in other human immune subsets remains incompletely understood. Mucosal associated invariant T (MAIT) cells uniformly express retin
Externí odkaz:
https://doaj.org/article/9977591d4c7042d0b21fe34563635126