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pro vyhledávání: '"Janine M. Morsman"'
Autor:
Margaret-Mary Ameyaw, Anne Indalo, Howard L. McLeod, David Ofori-Adjei, Janine M. Morsman, Jessie Githanga, Julieann Sludden
Publikováno v:
British Journal of Clinical Pharmacology. 50:269-272
Aims Dihydropyrimidine dehydrogenase (DPD) reduces endogenous pyrimidines and therapeutic analogues such as the anticancer agent 5-fluorouracil (5FU). Among Caucasian populations DPD activity is highly variable and subject to polymorphic regulation.