Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Janine M. Bekker"'
Autor:
Rachelle H. Crosbie, Janine M. Bekker, Kari M. Morrissey, Kent L. Hill, Jessica R. Colantonio, Sarah J. Kim
Publikováno v:
Traffic. 7:538-548
The mammalian GAS11 gene is a candidate tumor suppressor of unknown function that was previously identified as one of several genes upregulated upon growth arrest. Interestingly, although GAS11 homologs in Trypanosoma brucei (trypanin) and Chlamydomo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8148d84afebb5932717a957bf1e0f6c6
https://doi.org/10.1111/j.1600-0854.2006.00411.x
https://doi.org/10.1111/j.1600-0854.2006.00411.x
Autor:
Stephen M. Black, Janine M. Bekker, Michael J. Johengen, Jeffrey R. Fineman, Stephan Thelitz, Regan B. Stuart, Boaz Ovadia
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 127:1285-1292
BackgroundInhaled nitric oxide produces potent pulmonary vasodilation by activating soluble guanylate cyclase and increasing smooth muscle cell concentrations of cyclic guanosine monophosphate. However, responses are often nonsustained, and clinicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acc0f1e3d9ac940fee817eef2d86d89
https://doi.org/10.1016/j.jtcvs.2003.07.024
https://doi.org/10.1016/j.jtcvs.2003.07.024
Autor:
Lucienne S Sanchez, Michael J. Johengen, Janine M. Bekker, Peter Oishi, Jeffrey R. Fineman, Stephan Thelitz, Stephen M. Black, Boaz Ovadia
Publikováno v:
Pediatric Critical Care Medicine. 5:234-239
OBJECTIVES: To determine the effects of inhaled nitric oxide on endogenous cyclic adenosine monophosphate in the intact lamb, and to determine the potential role of cyclic adenosine monophosphate in the rebound pulmonary hypertension associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25be960e164e2fc9a486a8bdb7141915
https://doi.org/10.1097/01.pcc.0000124021.25393.2d
https://doi.org/10.1097/01.pcc.0000124021.25393.2d
Publikováno v:
DNA and Cell Biology. 22:317-328
Recent data has indicated that exogenous nitric oxide (NO) has the ability to decrease endogenous NO production by inhibiting the enzyme responsible for its generation, NO synthase (NOS). Our previous studies have indicated that increased generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f9f0705f193ecfd4f03f1e62c09442
https://doi.org/10.1089/104454903322216662
https://doi.org/10.1089/104454903322216662
Publikováno v:
Journal of Biological Chemistry. 278:934-939
Double-stranded RNA (dsRNA) interference is a potent mechanism for sequence-specific silencing of gene expression and represents an invaluable approach for investigating gene function in normal and diseased states as well as for drug target validatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea19883d2ad40a95c9add882109b06a1
https://doi.org/10.1074/jbc.m205946200
https://doi.org/10.1074/jbc.m205946200
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 281:L490-L498
We have shown that increased pulmonary blood flow at birth increases the activity and expression of endothelial nitric oxide (NO) synthase (eNOS). However, the signal transduction pathway regulating this process is unclear. Because protein kinase C (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d304d825ad6dd06f3d03aa2a8cb09d53
https://doi.org/10.1152/ajplung.2001.281.2.l490
https://doi.org/10.1152/ajplung.2001.281.2.l490
Autor:
D. Michael McMullan, Jeffrey R. Fineman, Stephen M. Black, R. Scott Heidersbach, Michael J. Johengen, Janine M. Bekker
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 277:H1849-H1856
Life-threatening increases in pulmonary vascular resistance have been noted on acute withdrawal of inhaled nitric oxide (NO), although the mechanisms remain unknown. In vitro data suggest that exogenous NO exposure inhibits endothelial NO synthase (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eacbef480ac9210e64e68209a8fda66
https://doi.org/10.1152/ajpheart.1999.277.5.h1849
https://doi.org/10.1152/ajpheart.1999.277.5.h1849
Publikováno v:
Pediatric Pulmonology. 28:3-11
Inhaled nitric oxide (NO) is currently used as an adjuvant therapy for a variety of pulmonary hypertensive disorders. In both animal and human studies, inhaled NO induces selective, dose-dependent pulmonary vasodilation. However, its potential intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4447107ed8d1972ea4e21ff9ebec9585
https://doi.org/10.1002/(sici)1099-0496(199907)28:1<3::aid-ppul2>3.0.co
https://doi.org/10.1002/(sici)1099-0496(199907)28:1<3::aid-ppul2>3.0.co
Publikováno v:
Molecular Brain Research. 64:165-178
PC12 cells are used as a model system to study neuronal differentiation. Nerve growth factor (NGF) triggers a differentiation pathway in PC12 cells. Neurite outgrowth (a morphological marker of differentiation) in PC12 cells is significantly reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f913081627655c58f89b2b2972e1c95b
https://doi.org/10.1016/s0169-328x(98)00315-5
https://doi.org/10.1016/s0169-328x(98)00315-5
Autor:
Christophe Guignabert, Niru Deshpande, Marlene Rabinovitch, Janine M. Bekker, Lingli Wang, Bin Zhou, Gordon M. Cann, Lihua Ying
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 237(1)
Murine light chain 3 (LC3) exists as two isoforms, LC3 and : LC3 is an RNA-binding protein that enhances fibronectin (FN) mRNA translation, and is also a marker of autophagy. We report embryonic expression patterns for LC3 and LC3, with some overlap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e0b720ed059c8d26f484856dbb31a7
https://pubmed.ncbi.nlm.nih.gov/18069693
https://pubmed.ncbi.nlm.nih.gov/18069693