Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janine L Coates"'
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14127 (2010)
The APC tumour suppressor functions in several cellular processes including the regulation of β-catenin in Wnt signalling and in cell adhesion and migration.In this study, we establish that in epithelial cells N-terminally phosphorylated β-catenin
Externí odkaz:
https://doaj.org/article/ba3adb8721fb4be1bc6e31d721ffba2d
Autor:
Christina Mølck, Frédéric Hollande, Laura M. Failla, Gregory D. Stewart, Joan K. Heath, Jean-Marc Pascussi, James G. Ryall, Janine L Coates
Publikováno v:
Cancer Letters. 383:135-143
Purpose Adenosine is a multifaceted regulator of tumor progression. It modulates immune cell activity as well as acting directly on tumor cells. The A 2b adenosine receptor (A 2b -AR) is thought to be an important mediator of these effects. In this s
Autor:
Stephen Mieruszynski, Janine L Coates, Tim Thomas, Sebastian Markmiller, Ben B. Williams, Karen Doggett, Joan K. Heath, Fan-Suo Geng, Matthias Ernst
Splicing is an essential step in eukaryotic gene expression. While the majority of introns is excised by the U2-dependent, or major class, spliceosome, the appropriate expression of a very small subset of genes depends on U12-dependent, or minor clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159771e1ec0dd8deac9c7af0293ab371
https://europepmc.org/articles/PMC6239176/
https://europepmc.org/articles/PMC6239176/
Autor:
Meredith J. Layton, Anthony W Burgess, Janine L Coates, Stephen H. Cody, Andrew H. A. Clayton, Maree C. Faux, Bruno Catimel
Publikováno v:
Oncogene. 27:5808-5820
The adenomatous polyposis coli (APC) tumour suppressor is a multifunctional protein involved in the regulation of Wnt signalling and cytoskeletal dynamics. Little is known about how APC controls these disparate functions. In this study, we have used
Autor:
Antony W. Burgess, Janine L Coates, Maree C. Faux, Nicole Church, Bruno Catimel, Kerryn Elliott, Meredith J. Layton
Publikováno v:
BMC Research Notes
BackgroundTheadenomatous polyposis coli(APC) tumour suppressor gene encodes a 2843 residue (310 kDa) protein. APC is a multifunctional protein involved in the regulation of β-catenin/Wnt signalling, cytoskeletal dynamics and cell adhesion.APCmutatio
Autor:
Janine L Coates, Nadia J. Kershaw, Richard J. Simpson, Eugene A. Kapp, Cameron J. Nowell, Bruno Catimel, Meredith J. Layton, Maree C. Faux, Nicole Church, Anthony W Burgess
Publikováno v:
Biochimica et biophysica acta. 1824(7)
β-catenin is a signaling protein with diverse functions in cell adhesion and Wnt signaling. Although β-catenin has been shown to participate in many protein-protein interactions, it is not clear which combinations of β-catenin-interacting proteins
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14127 (2010)
PLoS ONE
PLoS ONE
Background The APC tumour suppressor functions in several cellular processes including the regulation of β-catenin in Wnt signalling and in cell adhesion and migration. Findings In this study, we establish that in epithelial cells N-terminally phosp