Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janine E. Baaten"'
Autor:
Jeremy L. Jenkins, Katrin Volkmann, Shelly Meeusen, Prisca Liberali, Karyn Colman, Ludivine Challet Meylan, Michael B. Stadler, Ilya Lukonin, Janine E. Baaten, Denise Serra, Rui Zhao, Francisca Maurer
Publikováno v:
Nature
The development of intestinal organoids from single adult intestinal stem cells in vitro recapitulates the regenerative capacity of the intestinal epithelium1,2. Here we unravel the mechanisms that orchestrate both organoid formation and the regenera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aef2914c3fb4511271adaf18a1eeeef
https://doi.org/10.1038/s41586-020-2776-9
https://doi.org/10.1038/s41586-020-2776-9
Autor:
Bo Liu, Sukwon Ha, H. Michael Petrassi, Kate Jacobsen, George Harb, W. Perry Gordon, Bryan Laffitte, Thanh Lam, Qihui Jin, Yong Jia, Janine E. Baaten, Minhua Qiu, Robert Hill, Shelly Meeusen, Shanshan Yan, Badry Bursulaya, Valentina Molteni, Anwesh Kamireddy, Lisa Deaton, Jianfeng Pan, You-Qing Zhang, Loren Jon, Michael DiDonato, Yahu A. Liu, Shifeng Pan, Andrew M. Schumacher, Tingting Mo, Yefen Zou, Xiaoyue Zhang, Weijun Shen, Karyn Colman, Richard Glynne, Xueshi Hao, Peter McNamara, Vân Nguyen-Tran, Zhicheng Wang, Sheryll Espinola, Bao Nguyen, Tom Y.-H. Wu, Jing Li, Qiang Ding
Publikováno v:
Journal of Medicinal Chemistry. 63:2958-2973
Autoimmune deficiency and destruction in either β-cell mass or function can cause insufficient insulin levels and, as a result, hyperglycemia and diabetes. Thus, promoting β-cell proliferation could be one approach toward diabetes intervention. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222e5ae5085b8fd7b08c90167919a793
https://doi.org/10.1021/acs.jmedchem.9b01624
https://doi.org/10.1021/acs.jmedchem.9b01624
Autor:
Zhihong Huang, Bryan Laffitte, Yefen Zou, Weijun Shen, Ganesh Bhat, Bo Liu, Qiang Ding, Shanshan Yan, Yahu A. Liu, Richard Glynne, Tom Y.-H. Wu, Robert Hill, Matthew S. Tremblay, Shelly Meeusen, Valentina Molteni, Jing Li, Xueshi Hao, Van Nguyen-Tran, Yong Jia, Janine E. Baaten
Publikováno v:
ACS Omega, Vol 4, Iss 2, Pp 3571-3581 (2019)
Pancreatic β-cell apoptosis, a hallmark of the development of type 1 diabetes (T1D), is associated with increased levels of pro-inflammatory cytokines. Thus, an agent protecting β-cells from cytoki...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fe07c592dcafca39f735aad8a46b7e
https://doi.org/10.1021/acsomega.8b03050
https://doi.org/10.1021/acsomega.8b03050
Autor:
W. Perry Gordon, Tove Tuntland, Shelly Meeusen, Leah Clemmer, Sara Da Ros, Laura Bordone, Robert Hill, Thomas Hollenbeck, John W. Fathman, Kenneth Ng, Sheryll Espinola, Xiaohui He, Bo Liu, John Nelson, Maya Iskandar, Xue-Feng Zhu, Vân Nguyen-Tran, Andreas Kreusch, David C.S. Huang, Songchun Jiang, Yong Jia, Badry Bursulaya, Janine E. Baaten, Jian Shi, Mu-Yun Gao, Tao Jiang, Barun Okram, Glen Spraggon, Pierre-Yves Michellys, Hong Liu
Publikováno v:
ACS Medicinal Chemistry Letters. 8:1048-1053
NOD2 (nucleotide-binding oligomerization domain-containing protein 2) is an internal pattern recognition receptor that recognizes bacterial peptidoglycan and stimulates host immune responses. Dysfunction of NOD2 pathway has been associated with a num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c03b4d7782a1105eb048003151bbcc2
https://doi.org/10.1021/acsmedchemlett.7b00258
https://doi.org/10.1021/acsmedchemlett.7b00258
Autor:
Richard Glynne, Bryan Laffitte, Peter McNamara, George Harb, Weidong Wang, V. Deshmukh, Matthew S. Tremblay, Charles Y. Cho, You Qing Zhang, Ann E. Herman, Peter G. Schultz, Jonathan G. Swoboda, Janine E. Baaten, Weijun Shen, Tom Y.-H. Wu, Christophe M. Filippi, Jing Li, Qihui Jin, Anwesh Kamireddy, Xu Wu
Publikováno v:
Journal of the American Chemical Society. 135:1669-1672
The identification of factors that promote β cell proliferation could ultimately move type 1 diabetes treatment away from insulin injection therapy and toward a cure. We have performed high-throughput, cell-based screens using rodent β cell lines t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bd49122d522040efaa9a74797d00bd
https://doi.org/10.1021/ja309304m
https://doi.org/10.1021/ja309304m
Autor:
Adam L. Orr, Renata L.S. Goncalves, Edward K. Ainscow, H. Michael Petrassi, Irina V. Perevoshchikova, Martin D. Brand, Douglas C Quackenbush, Leonardo Vargas, Stephen J Attle, Shelly Meeusen, Carolina N. Turk, Jing Li, Janine E. Baaten, Jason T. Matzen, Victoria J. Dardov
Publikováno v:
Nature chemical biology
Mitochondrial electron transport drives ATP synthesis but also generates reactive oxygen species (ROS), which are both cellular signals and damaging oxidants. Superoxide production by respiratory complex III is implicated in diverse signaling events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e479961fe97e19cf3ff3afb0c5b3dfc
https://pubmed.ncbi.nlm.nih.gov/26485078
https://pubmed.ncbi.nlm.nih.gov/26485078
Autor:
Jing Li, Weidong Wang, Tom Wu, Jonathan G. Swoboda, Bryan A. Laffitte, Peter G. Schultz, Richard Glynne, Christophe M. Filippi, Qihui Jin, Weijun Shen, George Harb, Matthew S. Tremblay, Ann E. Herman, Charles Y. Cho, Eric C. Peters, Xu Wu, Janine E. Baaten, You Qing Zhang, Anwesh Kamireddy, Peter McNamara, V. Deshmukh
Publikováno v:
Journal of the American Chemical Society. 135:4573-4573
Page 1672. Eric C. Peters was mistakenly listed in the Acknowledgment of the published Communication rather than in the author list. Eric C. Peters should be included in the author list between Jonathan G. Swoboda and Charles Y. Cho, along with indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc271046574af3349f5003ca28b5f875
https://doi.org/10.1021/ja401118g
https://doi.org/10.1021/ja401118g