Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Janine C Fenton"'
Publikováno v:
PLoS Biology, Vol 9, Iss 8, p e1001133 (2011)
Organisms are structurally robust, as cells accommodate changes preserving structural integrity and function. The molecular mechanisms underlying structural robustness and plasticity are poorly understood, but can be investigated by probing how cells
Externí odkaz:
https://doaj.org/article/64016a298a9d423bb2f07aca4fb65480
Autor:
Bangfu Zhu, Jenny A Pennack, Peter McQuilton, Manuel G Forero, Kenji Mizuguchi, Ben Sutcliffe, Chun-Jing Gu, Janine C Fenton, Alicia Hidalgo
Publikováno v:
PLoS Biology, Vol 6, Iss 11, p e284 (2008)
Neurotrophic interactions occur in Drosophila, but to date, no neurotrophic factor had been found. Neurotrophins are the main vertebrate secreted signalling molecules that link nervous system structure and function: they regulate neuronal survival, t
Externí odkaz:
https://doaj.org/article/3920974e2c8c4f8aa84b63b899a3effa
Autor:
Surinder K. Chander, Delphine S. Fischer, L. W. Lawrence Woo, Janine C. Fenton, Atul Purohit, Barry V. L. Potter, Michael J. Reed
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 84:343-349
In pursuit of novel steroid sulfatase (STS) inhibitors devoid of estrogenicity, several D-ring modified steroid derivatives were synthesised. In vitro evaluation of the compounds identified two highly potent inhibitors, 4a and 4b, which were 18 times
Autor:
Graham McIlroy, Istvan Foldi, Jukka Aurikko, Jill S Wentzell, Mei Ann Lim, Janine C Fenton, Nicholas J Gay, Alicia Hidalgo
Publikováno v:
Nature neuroscience
Neurotrophin receptors corresponding to vertebrate Trk, p75(NTR) or Sortilin have not been identified in Drosophila, thus it is unknown how neurotrophism may be implemented in insects. Two Drosophila neurotrophins, DNT1 and DNT2, have nervous system