Výsledky vyhledávání - "Janine Bowring"

Akademický článek

The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature

Autor: J. Rafael Ciges-Tomas, Christian Alite, Suzanne Humphrey, J. Donderis, Janine Bowring, Xavier Salvatella, José R. Penadés, Alberto Marina

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

Staphylococcus aureus pathogenicity islands (SaPIs) encode the master repressor Stl and after bacteriophage infection Stl interacts with specific phage proteins leading to a derepression of SaPIs. Here the authors provide structural insights into thi

Externí odkaz: https://doaj.org/article/566f46134dd3427ca48ea42f87620741

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Akademický článek

Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilization.

Autor: Jorge Donderis, Janine Bowring, Elisa Maiques, J Rafael Ciges-Tomas, Christian Alite, Iltyar Mehmedov, María Angeles Tormo-Mas, José R Penadés, Alberto Marina

Publikováno v: PLoS Pathogens, Vol 13, Iss 9, p e1006581 (2017)

The dUTPase (Dut) enzymes, encoded by almost all free-living organisms and some viruses, prevent the misincorporation of uracil into DNA. We previously proposed that trimeric Duts are regulatory proteins involved in different cellular processes; incl

Externí odkaz: https://doaj.org/article/b685be69f65e4ca19b93269a06841113

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Akademický článek

Pirating conserved phage mechanisms promotes promiscuous staphylococcal pathogenicity island transfer

Autor: Janine Bowring, Maan M Neamah, Jorge Donderis, Ignacio Mir-Sanchis, Christian Alite, J Rafael Ciges-Tomas, Elisa Maiques, Iltyar Medmedov, Alberto Marina, José R Penadés

Publikováno v: eLife, Vol 6 (2017)

Targeting conserved and essential processes is a successful strategy to combat enemies. Remarkably, the clinically important Staphylococcus aureus pathogenicity islands (SaPIs) use this tactic to spread in nature. SaPIs reside passively in the host c

Externí odkaz: https://doaj.org/article/84a722f134d4403092f7b86bf3b7ca97

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The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature

Autor: Suzanne Humphrey, Janine Bowring, José R. Penadés, Christian Alite, Xavier Salvatella, Jorge Donderis, Alberto Marina, J. Rafael Ciges-Tomas

Publikováno v: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname

16 páginas, 7 figuras, 2 tablas. Coordinates and structure factors have been deposited in the Protein Data Bank under accession code 6H48, 6H4B, 6H49, 6H4C.
Stl is a master repressor encoded by Staphylococcus aureus pathogenicity islands (SaPIs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb3de05c6780204fc6ce4d577088478
http://hdl.handle.net/10044/1/80422

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Author response: Pirating conserved phage mechanisms promotes promiscuous staphylococcal pathogenicity island transfer

Autor: Janine Bowring, Maan M Neamah, Christian Alite, Iltyar Medmedov, José R. Penadés, Elisa Maiques, Alberto Marina, Ignacio Mir-Sanchis, J. Rafael Ciges-Tomas, Jorge Donderis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c261356070247d1004883fe74f6af695
https://doi.org/10.7554/elife.26487.034

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Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilization

Autor: Janine Bowring, Elisa Maiques, J. Rafael Ciges-Tomas, Alberto Marina, Jorge Donderis, Iltyar Mehmedov, Christian Alite, José R. Penadés, María Ángeles Tormo-Más

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 9, p e1006581 (2017)
CEU Repositorio Institucional
Fundación Universitaria San Pablo CEU (FUSPCEU)
PLOS Pathogens
PLOS PATHOGENS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

24 páginas, 6 figuras, 3 tablas
The dUTPase (Dut) enzymes, encoded by almost all free-living organisms and some viruses, prevent the misincorporation of uracil into DNA. We previously proposed that trimeric Duts are regulatory proteins involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79aa4e75796451328762673c08b56719
http://hdl.handle.net/10261/156457

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Another look at the mechanism involving trimeric dUTPases in Staphylococcus aureus pathogenicity island induction involves novel players in the party

Autor: Jorge Donderis, José R. Penadés, Alberto Marina, Janine Bowring, Nuria Quiles-Puchalt, Elisa Maiques, Suzanne Humphrey, J. Rafael Ciges-Tomas, Christian Alite

Publikováno v: Nucleic Acids Research
Digital.CSIC. Repositorio Institucional del CSIC
instname
CEU Repositorio Institucional
Fundación Universitaria San Pablo CEU (FUSPCEU)
'Nucleic Acids Research ', vol: 44, pages: 5457-5469 (2016)

13 páginas, 5 figuras, 3 tablas, material suplementario en NAR online
We have recently proposed that the trimeric staphylococcal phage encoded dUTPases (Duts) are signaling molecules that act analogously to eukaryotic G-proteins, using dUTP as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540ab929d276b2972b811e33792206c4
https://eprints.gla.ac.uk/118659/1/118659.pdf

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