Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Janine, Gotot"'
Autor:
Christoph Heuser, Janine Gotot, Eveline Christina Piotrowski, Marie-Sophie Philipp, Christina Johanna Felicia Courrèges, Martin Sylvester Otte, Linlin Guo, Jonathan Leo Schmid-Burgk, Veit Hornung, Annkristin Heine, Percy Alexander Knolle, Natalio Garbi, Edgar Serfling, César Evaristo, Friedrich Thaiss, Christian Kurts
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 578-586 (2017)
Regulatory T cells (Tregs) prevent autoimmunity but limit antitumor immunity. The canonical NF-κB signaling pathway both activates immunity and promotes thymic Treg development. Here, we report that mature Tregs continue to require NF-κB signaling
Externí odkaz:
https://doaj.org/article/4b8d2a01267d445e902b9141cf3081ba
Autor:
Isis Ludwig-Portugall, Hideo Yagita, Christian Kurts, Ermanila Dhana, Janine Gotot, Romina Kaiser
Publikováno v:
Immunology and Cell Biology. 96:852-862
Regulatory T cells (Tregs) maintain self-tolerance and prevent autoimmunity by controlling autoreactive T cells. We recently demonstrated in vivo that Tregs can directly suppress auto-reactive B cells via programmed death ligand 1 (PD-L1) that ligate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb19978c5c4a0ab6f07dfe5e5b2f46d
https://doi.org/10.1111/imcb.12053
https://doi.org/10.1111/imcb.12053
Autor:
Janine, Gotot, Ermanila, Dhana, Hideo, Yagita, Romina, Kaiser, Isis, Ludwig-Portugall, Christian, Kurts
Publikováno v:
Immunology and cell biology. 96(8)
Regulatory T cells (Tregs) maintain self-tolerance and prevent autoimmunity by controlling autoreactive T cells. We recently demonstrated in vivo that Tregs can directly suppress auto-reactive B cells via programmed death ligand 1 (PD-L1) that ligate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ab731b4f0fab604461f4daa5ea0a49b
https://pubmed.ncbi.nlm.nih.gov/29617057
https://pubmed.ncbi.nlm.nih.gov/29617057
Autor:
Cesar Evaristo, Christina Pitzka, Ramona Siemer, Anna Foerster-Marniok, Janine Gotot, Christian Dose, Anne Richter
Publikováno v:
The Journal of Immunology. 200:120.16-120.16
T cells play a central role in immunity to pathogens and tumors, but also in autoimmunity. T cell research has generated knowledge that led to multiple clinical breakthroughs, such as the generation of T cell vaccines and tumor immunotherapy approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0b4c1c69fc52c3aee45dffd4219abc1
https://doi.org/10.4049/jimmunol.200.supp.120.16
https://doi.org/10.4049/jimmunol.200.supp.120.16
Autor:
Guo Linlin, Eveline Piotrowski, Ulf Panzer, Friedrich Thaiss, Martin Sylvester Otte, Christian Kurts, Chen Yao, Natalio Garbi, André P. Tittel, Janine Gotot, Karl Ziegelbauer
The NFκB transcription factor family facilitates the activation of dendritic cells (DCs) and CD4(+) T helper (Th) cells, which are important for protective adaptive immunity. Inappropriate activation of these immune cells may cause inflammatory dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c19a8f9126306f03ba86bc2d1f21e07
https://europepmc.org/articles/PMC4926984/
https://europepmc.org/articles/PMC4926984/
Autor:
Kenneth M. Murphy, Hideo Yagita, Vera Damuzzo, Richard A. Kroczek, Janine Gotot, Isis Ludwig-Portugall, Christian Kurts, Percy A. Knolle, Catherine Gottschalk
Although the spleen is a major site where immune tolerance to circulating innocuous antigens occurs, the kidney also contributes. Circulating antigens smaller than albumin are constitutively filtered and concentrated in the kidney and reach the renal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c97b2d29e91dbca1c5d8c3c2ce24b2
http://hdl.handle.net/11577/3030918
http://hdl.handle.net/11577/3030918
Publikováno v:
European journal of immunology. 39(1)
To study B-cell tolerance against non-lymphoid tissue autoantigens, we generated transgenic rat insulin promoter (RIP)-OVA/hen egg lysozyme (HEL) mice expressing the model antigens, OVA and HEL, in pancreatic islets. Their vaccination with OVA or HEL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f3eb3475e52804e81915534ecbe711
https://pubmed.ncbi.nlm.nih.gov/19130585
https://pubmed.ncbi.nlm.nih.gov/19130585
Autor:
Christian Kurts, Isis Ludwig-Portugall, Emma E Hamilton-Williams, Catherine Gottschalk, Janine Gotot
Publikováno v:
The Journal of Immunology. 182:89.22-89.22
To study how peripheral B cell tolerance against non-lymphoid tissue autoantigens is maintained, we generated transgenic RIP-OVA/HEL (ROH) mice expressing the model antigens, OVA and HEL, in pancreatic islet beta cells. Immunization with OVA/HEL/alum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f461759b1f48d1ebdf0e48414f9325
https://doi.org/10.4049/jimmunol.182.supp.89.22
https://doi.org/10.4049/jimmunol.182.supp.89.22