Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Janina Remy"'
Autor:
Irina Kiprianova, Janina Remy, Nelli Milosch, Isabelle V. Mohrenz, Volker Seifert, Achim Aigner, Donat Kögel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 7, Pp 564-573 (2015)
The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is overactivated in malignant glioma and plays a key role in promoting cell survival, thereby increasing the acquired apoptosis resistance of these tumors.
Externí odkaz:
https://doaj.org/article/422273b6d3394659a937774385f82e3b
Autor:
Janina Remy, Benedikt Linder, Ulrike Weirauch, Bryan W. Day, Brett W. Stringer, Christel Herold-Mende, Achim Aigner, Knut Krohn, Donat Kögel
Publikováno v:
Cancers, Vol 14, Iss 339, p 339 (2022)
Cancers; Volume 14; Issue 2; Pages: 339
Cancers
Cancers; Volume 14; Issue 2; Pages: 339
Cancers
Simple Summary Glioblastoma is the most common primary brain cancer in adults. One reason for the development and malignancy of this tumor is the misregulation of certain cellular proteins. The oncoprotein STAT3 that is frequently overactive in gliob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e31c4f91787762a0f1e4a2733240e2
https://www.mdpi.com/2072-6694/14/2/339
https://www.mdpi.com/2072-6694/14/2/339
Autor:
Ulrike Weirauch, Rolf Marschalek, Donat Kögel, J. Konovalova, Janina Remy, Achim Aigner, Benedikt Linder
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:175-189
Overcoming apoptosis resistance is one major issue in glioblastoma (GB) therapies. Accumulating evidence indicates that resistance to apoptosis in GB is mediated via upregulation of pro-survival BCL2-family members. The synthetic BH3-mimetic ABT-737
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae111d6d667970142b030d11ef6ed2d
https://doi.org/10.1016/j.bbamcr.2018.10.017
https://doi.org/10.1016/j.bbamcr.2018.10.017