Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Janina Reeder"'
Autor:
Eric M. Kofoed, Ignacio Aliagas, Terry Crawford, Jialin Mao, Seth F. Harris, Min Xu, Shumei Wang, Ping Wu, Fang Ma, Kevin Clark, Jessica Sims, Yiming Xu, Yutian Peng, Elizabeth Skippington, Ying Yang, Janina Reeder, Savita Ubhayakar, Matt Baumgardner, Zhengyin Yan, Jacob Chen, Summer Park, Hua Zhang, Chun-Wan Yen, Maria Lorenzo, Nicholas Skelton, Xiaorong Liang, Liuxi Chen, Bridget Hoag, Chun Sing Li, Zhiguo Liu, John Wai, Xingrong Liu, Jun Liang, Man Wah Tan
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Guanine nucleotides are required for growth and viability of cells due to their structural role in DNA and RNA, and their regulatory roles in translation, signal transduction, and cell division. The natural antibiotic mycophenolic acid (MPA)
Externí odkaz:
https://doaj.org/article/92da914a1cc64fff8b2ab55b0e41acbf
Autor:
Homer Pantua, Elizabeth Skippington, Marie-Gabrielle Braun, Cameron L. Noland, Jingyu Diao, Yutian Peng, Susan L. Gloor, Donghong Yan, Jing Kang, Anand Kumar Katakam, Janina Reeder, Georgette M. Castanedo, Keira Garland, Laszlo Komuves, Meredith Sagolla, Cary D. Austin, Jeremy Murray, Yiming Xu, Zora Modrusan, Min Xu, Emily J. Hanan, Sharookh B. Kapadia
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Clinical development of antibiotics with novel mechanisms of action to kill pathogenic bacteria is challenging, in part, due to the inevitable emergence of resistance. A phenomenon of potential clinical importance that is broadly overlooked
Externí odkaz:
https://doaj.org/article/ad7dc0127d394ca78d233d455e860331
Autor:
Anh Miu, Benjamin D. Sellers, Maria Ruiz-Gonzalez, Jian Payandeh, Peter Liu, L. Martin, Kerry R Buchholz, Dewakar Sangaraju, Guanghui Han, Mark S. Hunter, Elizabeth Skippington, Wendy Sandoval, Emily J. Hanan, Cameron L. Noland, Trisha Dela Vega, Daniel P. DePonte, Erik Verschueren, Danielle L. Swem, Min Xu, Sheerin K. Shahidi-Latham, Nicholas N. Nickerson, Summer Park, Steven T. Rutherford, Nicholas J. Skelton, Qingling Li, Janina Reeder, Kelly M. Storek, Cornelius Gati, Thomas Clairfeuille
Publikováno v:
Nature. 584:479-483
Lipopolysaccharide (LPS) resides in the outer membrane of Gram-negative bacteria where it is responsible for barrier function1,2. LPS can cause death as a result of septic shock, and its lipid A core is the target of polymyxin antibiotics3,4. Despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60f6821b117c57797c53d6a1fae98ab
https://doi.org/10.1038/s41586-020-2597-x
https://doi.org/10.1038/s41586-020-2597-x
Autor:
Eric M. Kofoed, Russell E. Vance, Man-Wah Tan, Tommy K. Cheung, Yuxin Liang, Giovanni Luchetti, Christopher M. Rose, Justin L. Roncaioli, Elizabeth Skippington, Kim Newton, Janina Reeder, Vishva M. Dixit, Alexander F. Schubert, Rohit Reja, Benjamin Haley, Nobuhiko Kayagaki, Roberto A. Chavez, Isabelle Lehoux, Joshua D. Webster
Publikováno v:
Cell Host Microbe
Summary The pore-forming protein gasdermin D (GSDMD) executes lytic cell death called pyroptosis to eliminate the replicative niche of intracellular pathogens. Evolution favors pathogens that circumvent this host defense mechanism. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35137471dfdcf537a68417e65484c59f
https://europepmc.org/articles/PMC9122893/
https://europepmc.org/articles/PMC9122893/
Autor:
Steffen Durinck, Joshua S. Kaminker, Janina Reeder, Hany S. Girgis, Elizabeth Skippington, Yuxin Liang, Cory D. DuPai, Joseph Guillory, Peter A. S. Smith, Jessica Lund
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Genetic heterogeneity is a significant driver of antibiotic resistance in bacteria. Understanding copy number (CN) heterogeneity is important because minority subclones with increased CN can drive resistance during antibiotic exposure, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a607f4eb7aad6d2fa04f503519e62129
http://europepmc.org/articles/PMC7817135
http://europepmc.org/articles/PMC7817135
Publikováno v:
Bioinformatics
Summary We developed the MicrobiomeExplorer R package to facilitate the analysis and visualization of microbial communities. The MicrobiomeExplorer R package allows a user to perform typical microbiome analytic workflows and visualize their results,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bba0668d2c14929d4fab1083d59869d
https://doi.org/10.1093/bioinformatics/btaa838
https://doi.org/10.1093/bioinformatics/btaa838
Autor:
Paul J. Wolters, Julie Hunkapiller, Christopher R. Cabanski, William F. Forrest, Lisa Lancaster, Timothy S. Blackwell, Jan Vogel, Jonathan A. Kropski, Kiran Mukhyala, Amy Cowgill, Joseph R. Arron, Thirumalai R. Ramalingam, Janina Reeder, Jens Reeder, Tushar Bhangale, Matthew J. Brauer, Alexander R. Abbas, Karen Cuenco, Amy Dressen, Harold R. Collard, Jennifer Tom, Brian L. Yaspan, Margaret Neighbors
Publikováno v:
The Lancet. Respiratory medicine, vol 6, iss 8
Summary Background Idiopathic pulmonary fibrosis (IPF) risk has a strong genetic component. Studies have implicated variations at several loci, including TERT , surfactant genes, and a single nucleotide polymorphism at chr11p15 (rs35705950) in the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86492593cec9b6e7d82194c499c48804
https://europepmc.org/articles/PMC6487850/
https://europepmc.org/articles/PMC6487850/
Autor:
Robert Giegerich, Janina Reeder
Publikováno v:
GPCE
We describe a graphical programming system for a domain specific language in biosequence analysis. It supports the development of programs for RNA structure prediction and motif search, created by biologists with little or no programming skills. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d3f578676583145ff7416787f0bb03
https://pub.uni-bielefeld.de/record/2383518
https://pub.uni-bielefeld.de/record/2383518
Publikováno v:
BMC Bioinformatics. 6:153
Ambiguity is a problem in biosequence analysis that arises in various analysis tasks solved via dynamic programming, and in particular, in the modeling of families of RNA secondary structures with stochastic context free grammars. Several types of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3038daeebe21e6ee8035d55fda37766a
https://doi.org/10.1186/1471-2105-6-153
https://doi.org/10.1186/1471-2105-6-153
Publikováno v:
Bioinformatics. Jul2007, Vol. 23 Issue 13, pi392-i392. 1p.