Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janina Mielke"'
Autor:
Benedikt Kretner, Johannes Trambauer, Akio Fukumori, Janina Mielke, Peer‐Hendrik Kuhn, Elisabeth Kremmer, Armin Giese, Stefan F Lichtenthaler, Christian Haass, Thomas Arzberger, Harald Steiner
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 5, Pp 458-465 (2016)
Abstract As stated by the prevailing amyloid cascade hypothesis, Alzheimer's disease (AD) is caused by the aggregation and cerebral deposition of long amyloid‐β peptide (Aβ) species, which are released from a C‐terminal amyloid precursor protei
Externí odkaz:
https://doaj.org/article/57489df83deb47b496e7a64e1e5c8050
Autor:
Sabina Eigenbrod, Petra Frick, Uwe Bertsch, Gerda Mitteregger-Kretzschmar, Janina Mielke, Marko Maringer, Niklas Piening, Alexander Hepp, Nathalie Daude, Otto Windl, Johannes Levin, Armin Giese, Vignesh Sakthivelu, Jörg Tatzelt, Hans Kretzschmar, David Westaway
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188989 (2017)
Prion diseases have been linked to impaired copper homeostasis and copper induced-oxidative damage to the brain. Divalent metal ions, such as Cu2+ and Zn2+, bind to cellular prion protein (PrPC) at octapeptide repeat (OR) and non-OR sites within the
Externí odkaz:
https://doaj.org/article/768e6387c51240a48de92b6362f601c9
Autor:
Sabina Eigenbrod, Niklas Thon, Nathalie Jansen, Hendrik Janssen, Janina Mielke, Michael Ruiter, Christian la Fougère, Aurelia Peraud, Rupert Egensperger, Hans Kretzschmar
Publikováno v:
Rare Tumors, Vol 4, Iss 2, Pp e30-e30 (2012)
Intramedullary glioma are rare and their biological behaviour can differ from their cerebral counterparts. Pilomyxoid astrocytoma (PMA, WHO grade II), predominantly occur in the hypothalamic/chiasmatic region of infants and children. The few reported
Externí odkaz:
https://doaj.org/article/ced129ffcdc5483090394d46357efb9f
Autor:
Nils Briel, Viktoria C. Ruf, Katrin Pratsch, Sigrun Roeber, Jeannine Widmann, Janina Mielke, Mario M. Dorostkar, Otto Windl, Thomas Arzberger, Jochen Herms, Felix L. Struebing
Publikováno v:
Acta neuropathologica 144(4), 615-635 (2022). doi:10.1007/s00401-022-02483-8
Tauopathies such as progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) exhibit characteristic neuronal and glial inclusions of hyperphosphorylated Tau (pTau). Although the astrocytic pTau phenotype upon neuropathological examina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da7217a07904d2202bc329eb4a73102
https://pubmed.ncbi.nlm.nih.gov/35976433
https://pubmed.ncbi.nlm.nih.gov/35976433
Autor:
Hans A. Kretzschmar, Marko Maringer, Nathalie Daude, Alexander Hepp, David Westaway, Gerda Mitteregger-Kretzschmar, Janina Mielke, Sabina Eigenbrod, Armin Giese, Petra Frick, Vignesh Sakthivelu, Jörg Tatzelt, Uwe Bertsch, Otto Windl, Niklas Piening, Johannes Levin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0188989 (2017)
PLOS ONE 12(12), e0188989 (2017). doi:10.1371/journal.pone.0188989
PLoS ONE, Vol 12, Iss 12, p e0188989 (2017)
PLOS ONE 12(12), e0188989 (2017). doi:10.1371/journal.pone.0188989
Prion diseases have been linked to impaired copper homeostasis and copper induced-oxidative damage to the brain. Divalent metal ions, such as Cu2+ and Zn2+, bind to cellular prion protein (PrPC) at octapeptide repeat (OR) and non-OR sites within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe04532615df3576b97bd80efd02003
https://pubmed.ncbi.nlm.nih.gov/29220360
https://pubmed.ncbi.nlm.nih.gov/29220360
Autor:
Harald Steiner, Armin Giese, Thomas Arzberger, Christian Haass, Benedikt Kretner, Janina Mielke, Akio Fukumori, Elisabeth Kremmer, Peer-Hendrik Kuhn, Stefan F. Lichtenthaler, Johannes Trambauer
Publikováno v:
EMBO molecular medicine 8(5), 458-465 (2016). doi:10.15252/emmm.201505952
EMBO Molecular Medicine
EMBO Molecular Medicine
As stated by the prevailing amyloid cascade hypothesis, Alzheimer's disease (AD) is caused by the aggregation and cerebral deposition of long amyloid‐β peptide (Aβ) species, which are released from a C‐terminal amyloid precursor protein fragmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a36f51821741182e68cb45ec796ad96
https://pub.dzne.de/record/138553
https://pub.dzne.de/record/138553
Autor:
Hendrik Janssen, Sabina Eigenbrod, Hans A. Kretzschmar, Christian la Fougère, Rupert Egensperger, Aurelia Peraud, Nathalie Jansen, Michael Ruiter, Janina Mielke, Niklas Thon
Publikováno v:
Rare Tumors, Vol 4, Iss 2, Pp e30-e30 (2012)
Rare Tumors
Rare Tumors
Intramedullary glioma are rare and their biological behaviour can differ from their cerebral counterparts. Pilomyxoid astrocytoma (PMA, WHO grade II), predominantly occur in the hypothalamic/chiasmatic region of infants and children. The few reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c46f806f3c37b1dd763419d2538560b
http://www.pagepress.org/journals/index.php/rt/article/view/4063
http://www.pagepress.org/journals/index.php/rt/article/view/4063