Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Janina Frisch"'
Autor:
Julia Wollenhaupt, Janina Frisch, Eva Harlacher, Dickson W.L. Wong, Han Jin, Corinna Schulte, Sonja Vondenhoff, Julia Moellmann, Barbara Mara Klinkhammer, Li Zhang, Adelina Baleanu-Curaj, Elisa A. Liehn, Thimoteus Speer, Andrey Kazakov, Christian Werner, Emiel P.C. van der Vorst, Simina-Ramona Selejan, Mathias Hohl, Michael Böhm, Rafael Kramann, Erik A.L. Biessen, Michael Lehrke, Nikolaus Marx, Joachim Jankowski, Christoph Maack, Peter Boor, Leticia Prates Roma, Heidi Noels
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102459- (2022)
Aims: Patients with chronic kidney disease (CKD) have an increased risk of cardiovascular events and exhibit myocardial changes including left ventricular (LV) hypertrophy and fibrosis, overall referred to as ‘uremic cardiomyopathy’. Although dif
Externí odkaz:
https://doaj.org/article/da483e5c15e143c481fbb9e3d6886c99
Autor:
Jagadeesh K. Venkatesan, Janina Frisch, Ana Rey-Rico, Gertrud Schmitt, Henning Madry, Magali Cucchiarini
Publikováno v:
Journal of Experimental Orthopaedics, Vol 4, Iss 1, Pp 1-13 (2017)
Abstract Background Evaluation of gene-based approaches to target human bone marrow aspirates in conditions of mechanical stimulation that aim at reproducing the natural joint environment may allow to develop improved treatments for articular cartila
Externí odkaz:
https://doaj.org/article/2cd077524df04c79a6942220548c9f8a
Autor:
Johanna Reul, Janina Frisch, Christine E. Engeland, Frederic B. Thalheimer, Jessica Hartmann, Guy Ungerechts, Christian J. Buchholz
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Immune checkpoint inhibitors (ICIs) can block distinct receptors on T cells or tumor cells thus preventing T cell inactivation and tumor immune escape. While the clinical response to treatment with ICIs in cancer patients is impressive, this therapy
Externí odkaz:
https://doaj.org/article/c9b2651adab048cc8ecea4b5e41846c3
Autor:
Oliver Daniels, Janina Frisch, Jagadeesh K. Venkatesan, Ana Rey-Rico, Gertrud Schmitt, Magali Cucchiarini
Publikováno v:
Journal of Clinical Medicine, Vol 8, Iss 10, p 1637 (2019)
Gene therapy for osteoarthritis offers powerful, long-lasting tools that are well adapted to treat such a slow, progressive disorder, especially those therapies based on the clinically adapted recombinant adeno-associated viral (rAAV) vectors. Here,
Externí odkaz:
https://doaj.org/article/faf53e3aaf3b49478e0a446930f85204
Publikováno v:
Cancers, Vol 11, Iss 4, p 457 (2019)
The tumor microenvironment (TME) is shaped by cancer and noncancerous cells, the extracellular matrix, soluble factors, and blood vessels. Interactions between the cells, matrix, soluble factors, and blood vessels generate this complex heterogeneous
Externí odkaz:
https://doaj.org/article/b4fdf1c227e24e42be81332d45b259a7
Autor:
Janina Frisch, Jagadeesh K. Venkatesan, Ana Rey‐Rico, Adam M. Zawada, Gertrud Schmitt, Henning Madry, Magali Cucchiarini
Publikováno v:
Journal of Experimental Orthopaedics, Vol 3, Iss 1, Pp n/a-n/a (2016)
Abstract Background Application of genetically modified bone marrow concentrates in articular cartilage lesions is a promising approach to enhance cartilage repair by stimulating the chondrogenic differentiation processes in sites of injury. Method I
Externí odkaz:
https://doaj.org/article/d709afaa0d3b4fb19ac4ea47f437224b
Publikováno v:
Clinical Kidney Journal.
The cardiorenal syndrome (CRS) is described as a multi-organ disease encompassing bidirectionally heart and kidney. In CRS type 4, chronic kidney disease (CKD) leads to cardiac injury. Different pathological mechanisms have been identified to contrib
Autor:
Simon Wittmann, Ann‐Cathrin Wolf, Sarah Lukas, Nina Seiwert, Lilli Zinnert, Katharina M. Rund, Janina Frisch, Leticia Prates‐Roma, Nils H. Schebb, Tasuku Hirayama, Jörg Fahrer
Publikováno v:
Lebensmittelchemie. 77
Autor:
Rafael Kramann, Emiel P. C. van der Vorst, Julia Wirth, Mathias Hohl, Nikolaus Marx, Christian Hemmers, Heidi Noels, Julia Moellmann, Josefin Soppert, Michael Lehrke, Thimoteus Speer, Sonja Vondenhoff, Christian Werner, Peter Boor, Leticia Prates Roma, Christoph Maack, Janina Frisch, Joachim Jankowski
Publikováno v:
Kidney international 101(2), 256-273 (2022). doi:10.1016/j.kint.2021.10.025
Kidney international 101(2), 256-273 (2022). doi:10.1016/j.kint.2021.10.025
Published by Elsevier, New York, NY
Published by Elsevier, New York, NY
Autor:
Jagadeesh K. Venkatesan, Franklin T. Moutos, Farshid Guilak, Janina Frisch, Ana Rey-Rico, Magali Cucchiarini, Gertrud Schmitt, Bradley T. Estes, Henning Madry
Publikováno v:
Human Gene Therapy. 29:1277-1286
Combining gene therapy approaches with tissue engineering procedures is an active area of translational research for the effective treatment of articular cartilage lesions, especially to target chondrogenic progenitor cells such as those derived from