Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Janina Deutschmann"'
Autor:
Stephan Klessing, Antonia Sophia Peter, Kirsten Fraedrich, Jannik T. Wagner, Mirko Kummer, Janina Deutschmann, Philipp Steininger, Hans-Dieter Steibl, Klaus Überla
Publikováno v:
Viruses, Vol 15, Iss 2, p 397 (2023)
Live-attenuated SARS-CoV-2 vaccines present themselves as a promising approach for the induction of broad mucosal immunity. However, for initial safety assessment in clinical trials, virus production requires conditions meeting Good Manufacturing Pra
Externí odkaz:
https://doaj.org/article/cef303dff024458ca4eb53d2e12b97eb
Autor:
Janina Deutschmann, Thomas Gramberg
Publikováno v:
Viruses, Vol 13, Iss 3, p 395 (2021)
The SAM and HD domain-containing protein 1 (SAMHD1) is a dNTP triphosphohydrolase that plays a crucial role for a variety of different cellular functions. Besides balancing intracellular dNTP concentrations, facilitating DNA damage repair, and dampen
Externí odkaz:
https://doaj.org/article/8c04285eaedd403abcfd7b11547e795b
Autor:
Alina Russ, Sabine Wittmann, Yuta Tsukamoto, Alexandra Herrmann, Janina Deutschmann, Justine Lagisquet, Armin Ensser, Hiroki Kato, Thomas Gramberg
Publikováno v:
EMBO reports. 23
Methylation of the mRNA 5′ cap by cellular methyltransferases enables efficient translation and avoids recognition by innate immune factors. Coronaviruses encode viral 2′‐O‐methyltransferases to shield their RNA from host factors. Here, we ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb979cb0e161af42cba7e6633840174e
https://doi.org/10.15252/embr.202255648
https://doi.org/10.15252/embr.202255648
Autor:
Jens Milbradt, Andrea Schneider, Alexandra Herrmann, Thomas Gramberg, Melissa Kießling, Iris Gruska, Nerea Ferreirós, Sabine Wittmann, Janina Deutschmann, Thomas Winkler, Barbara Vetter, Lüder Wiebusch, Dominique Thomas, Michael Schindler
Publikováno v:
Nature Microbiology. 4:2273-2284
The deoxynucleotide triphosphate (dNTP) hydrolase SAMHD1 inhibits retroviruses in non-dividing myeloid cells. Although antiviral activity towards DNA viruses has also been demonstrated, the role of SAMHD1 during cytomegalovirus (CMV) infection remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a2d9b2406be567161ef66a50fad4f92
https://doi.org/10.1038/s41564-019-0529-z
https://doi.org/10.1038/s41564-019-0529-z
Autor:
Justine Lagisquet, Thomas Gramberg, Sabine Wittmann, Brigitte Biesinger, James Julian Ross, Bianca Volkmann, Kristin Eissmann, Janina Deutschmann
Publikováno v:
Proc Natl Acad Sci U S A
Mobile genetic elements have significantly shaped our genomic landscape. LINE-1 retroelements are the only autonomously active elements left in the human genome. Since new insertions can have detrimental consequences, cells need to efficiently contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0558f9af500d1d1a783685f785e210b3
https://pubmed.ncbi.nlm.nih.gov/32651277
https://pubmed.ncbi.nlm.nih.gov/32651277
Autor:
Janina, Deutschmann, Andrea, Schneider, Iris, Gruska, Barbara, Vetter, Dominique, Thomas, Melissa, Kießling, Sabine, Wittmann, Alexandra, Herrmann, Michael, Schindler, Jens, Milbradt, Nerea, Ferreirós, Thomas H, Winkler, Lüder, Wiebusch, Thomas, Gramberg
Publikováno v:
Nature microbiology. 4(12)
The deoxynucleotide triphosphate (dNTP) hydrolase SAMHD1 inhibits retroviruses in non-dividing myeloid cells. Although antiviral activity towards DNA viruses has also been demonstrated, the role of SAMHD1 during cytomegalovirus (CMV) infection remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09514f9337681efdbce0e3f6f897b793
https://pubmed.ncbi.nlm.nih.gov/31548683
https://pubmed.ncbi.nlm.nih.gov/31548683
Autor:
Lueder Wiebusch, Jens Milbradt, Iris Gruska, Ramona Businger, Michael Schindler, Janina Deutschmann, Thomas Gramberg
Publikováno v:
Nature microbiology. 4(12)
The host restriction factor sterile alpha motif and histidine–aspartate domain-containing protein 1 (SAMHD1) is an important component of the innate immune system. By regulating the intracellular nucleotide pool, SAMHD1 influences cell division and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cc926271168bad788430e35362c7b5
https://pubmed.ncbi.nlm.nih.gov/31548682
https://pubmed.ncbi.nlm.nih.gov/31548682