Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Janina, Pfaff"'
Autor:
Robert Kopf, Denis Klemm, Tobias Graf, Christoph A. Paschen, Christian Bell, Claudia Müller, Janina Pfaff, Cosimo Pinto
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 192
Polysorbates and Poloxamer 188 constitute the most common surfactants used in biopharmaceutical formulations owing to their excellent protein-stabilizing properties and good safety profiles. In recent years, however, a vast number of reports concerni
Autor:
Gunter Meister, Janina Pfaff
Publikováno v:
Biochemical Society Transactions. 41:855-860
Argonaute proteins interact with small RNAs and facilitate small RNA-guided gene-silencing processes. Small RNAs guide Argonaute proteins to distinct target sites on mRNAs where Argonaute proteins interact with members of the GW182 protein family (al
Publikováno v:
Nature Structural & Molecular Biology; Vol 20
Argonaute proteins interact with small RNAs that guide them to complementary target RNAs, thus leading to inhibition of gene expression. Some but not all Argonaute proteins are endonucleases and can cleave the complementary target RNA. Here, we have
Autor:
Janina Pfaff, Sudhir Manickavel, Leonhard Jakob, Judith Hauptmann, Stefanie Sprunck, Rainer Deutzmann, Markus Hafner, Gunter Meister, Daniel Schraivogel, Marc Urban, Thomas Tuschl, Norbert Eichner, Astrid Bruckmann
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(38)
Significance Small RNA-guided gene-silencing pathways regulate fundamental cellular processes. Small RNAs such as microRNAs (miRNAs) directly bind to a member of the Argonaute (Ago) protein family. In animals, Ago proteins interact with a member of t
Autor:
Daniel, Schraivogel, Susann G, Schindler, Johannes, Danner, Elisabeth, Kremmer, Janina, Pfaff, Stefan, Hannus, Reinhard, Depping, Gunter, Meister
Publikováno v:
Nucleic Acids Res. 43, 7447-7461 (2015)
Nucleic Acids Research
Nucleic Acids Research
MicroRNAs (miRNAs) guide Argonaute (Ago) proteins to distinct target mRNAs leading to translational repression and mRNA decay. Ago proteins interact with a member of the GW protein family, referred to as TNRC6A-C in mammals, which coordinate downstre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::97949ec6071604f221a47e6c4ca16234
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=46322
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=46322
Autor:
Dierk Niessing, Michael Sattler, Franz Herzog, Ruedi Aebersold, Gunter Meister, Janina Pfaff, Janosch Hennig
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 110, 3770-3779 (2013)
MicroRNAs (miRNAs) guide Argonaute (Ago) proteins to target mRNAs, leading to gene silencing. However, Ago proteins are not the actual mediators of gene silencing but interact with a member of the GW182 protein family (also known as GW proteins), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d4e6ab2484fd08b4b8245a1005b11c
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=27266
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=27266