Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Janice W, Smith"'
Autor:
Gary Gilmour, Dale M. Edgar, Francois Gastambide, Lorena Taboada, Beverly A. Heinz, Elaine Shanks, Brian G. Getman, Lourdes Prieto, Janice W. Smith, Lisa M. Broad, Thomas C. Britton, Keith A. Wafford, Adam M. Fivush, Mark D. Tricklebank, Andrew McCarthy, Ellen M. Colvin
Publikováno v:
Neuropharmacology. 64:224-239
The demonstrated functional interaction of metabotropic glutamate 5 (mGlu₅) receptors with N-methyl-d-aspartate (NMDA) receptors has prompted speculation that their activation may offer a potential treatment for aspects of schizophrenia. Developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::499e6fd6587a804b5c1c9dc77cbb6b56
https://doi.org/10.1016/j.neuropharm.2012.07.030
https://doi.org/10.1016/j.neuropharm.2012.07.030
Autor:
Mark J. Benvenga, Michael A. Statnick, Karen M. Knitowski, Julie Foss, Miguel A. Toledo, Alfonso Benito, Anke Post, Kirsti Lloyd, Michael Ansonoff, Alma Jiménez, Vanessa N. Barth, Maria Angeles Martinez-Grau, Janice W. Smith, Scott D. Gleason, Celia Lafuente, Linda M. Rorick-Kehn, John T. Catlow, Conception Pedregal, Nuria Diaz, Julie F. Falcone, Kjell A. Svensson, John E. Pintar, Steven Chaney, Xia Li, David L. McKinzie, Benjamin L. Adams, Jeffrey M. Witkin
Publikováno v:
Pharmacology Research & Perspectives
Nociceptin/Orphanin FQ (N/OFQ) is a 17 amino acid peptide whose receptor is designated ORL1 or nociceptin receptor (NOP). We utilized a potent, selective, and orally bioavailable antagonist with documented engagement with NOP receptors in vivo to ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1cbf123c707e4aba252f069cf2e98ce
http://europepmc.org/articles/PMC5226289
http://europepmc.org/articles/PMC5226289
Autor:
Sofia I. H. Godinho, Rachel Butler, Stuart N. Peirson, Sheena Lee, Janice W. Smith, Kay E. Davies, Melanie V. Sobczyk, Achilleas Livieratos, Benjamin Edwards, Henrik Oster, Russell G. Foster, Peter L. Oliver, Johanna E. Chesham, Simon P. Fisher, Katharina Wulff, Michael H. Hastings, Elizabeth S. Maywood
Publikováno v:
Current Biology
Summary Sleep and circadian rhythm disruption has been widely observed in neuropsychiatric disorders including schizophrenia [1] and often precedes related symptoms [2]. However, mechanistic basis for this association remains unknown. Therefore, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec9b49e2d521e96e422193c975314dc
http://europepmc.org/articles/PMC3356578
http://europepmc.org/articles/PMC3356578
Autor:
Janice W. Smith, Julie Foss, Kirstie J. Lloyd, Sophie Dix, Gary Gilmour, Francois Gastambide, Nadia Malik, Mark D. Tricklebank
Publikováno v:
Psychopharmacology. 217:255-269
N-methyl-d-Aspartate receptor (NMDAR) antagonists such as ketamine induce cognitive symptoms in man similar to those of schizophrenia and therefore might be useful as models of the disease in animals. However, it is unclear which NMDAR antagonist(s)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a3dfdb8d2122f07d465e3a5df0bdeb
https://doi.org/10.1007/s00213-011-2277-5
https://doi.org/10.1007/s00213-011-2277-5
Autor:
Rebecca Mason, Michael W. Conway, Wendy T. Jones, Gary Gilmour, Sally Loomis, Elsa Y. Pioli, Sophie Dix, Shahram Shahabi, Mark D. Tricklebank, Janice W. Smith
Publikováno v:
Psychopharmacology. 205:203-216
Little attention has been paid to the relative equivalence of behavioural effects of NMDA receptor antagonists in rodents, with different compounds often used interchangeably to “model” aspects of schizophrenia in preclinical studies. To further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0422a3f08a7e43b1b1f155cbd2b8801f
https://doi.org/10.1007/s00213-009-1530-7
https://doi.org/10.1007/s00213-009-1530-7
Autor:
Adrian J. Mogg, Philip G. Szekeres, Elisiana Tafi, Ian A. Pullar, Mark D. Tricklebank, Janice W. Smith, Eleanor Peacey
Publikováno v:
Psychopharmacology. 190:157-170
Nicotine produces behavioural effects that are potentially related to its interaction with diverse nicotinic acetylcholine receptor populations. Evidence from gene deletion studies suggests that the interoceptive stimulus properties of nicotine are m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af5622737df89ff417c0aee9c750601b
https://doi.org/10.1007/s00213-006-0596-8
https://doi.org/10.1007/s00213-006-0596-8
Autor:
Gary, Gilmour, Lisa M, Broad, Keith A, Wafford, Thomas, Britton, Ellen M, Colvin, Adam, Fivush, Francois, Gastambide, Brian, Getman, Beverly A, Heinz, Andrew P, McCarthy, Lourdes, Prieto, Elaine, Shanks, Janice W, Smith, Lorena, Taboada, Dale M, Edgar, Mark D, Tricklebank
Publikováno v:
Neuropharmacology. 64
The demonstrated functional interaction of metabotropic glutamate 5 (mGlu₅) receptors with N-methyl-d-aspartate (NMDA) receptors has prompted speculation that their activation may offer a potential treatment for aspects of schizophrenia. Developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e820baac04ef54382d7935c0d5fbb548
https://pubmed.ncbi.nlm.nih.gov/22884720
https://pubmed.ncbi.nlm.nih.gov/22884720
Publikováno v:
Psychopharmacology. 212(2)
The range of cognitive and psychotomimetic effects produced by antagonists of the N-methyl-D-aspartate (NMDA) receptor has lead to widespread usage of these molecules as pharmacological models of cognitive impairment for drug discovery. Historically,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db208c8156ed39071afb3dbe7de515d0
https://pubmed.ncbi.nlm.nih.gov/20676612
https://pubmed.ncbi.nlm.nih.gov/20676612
Autor:
Janice W, Smith, Ian P, Stolerman
Publikováno v:
Handbook of experimental pharmacology. (192)
Drug discrimination methodology makes possible the objective, quantitative study of the perception of psychoactive drug effects in either human or animal subjects. Investigations of the nicotine discriminative stimulus complex have contributed to our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75d7b3da1cc7a2e5cb5c1a6c44d7067e
https://pubmed.ncbi.nlm.nih.gov/19184654
https://pubmed.ncbi.nlm.nih.gov/19184654
Autor:
Janice W. Smith, Ian P. Stolerman
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783540692461
Drug discrimination methodology makes possible the objective, quantitative study of the perception of psychoactive drug effects in either human or animal subjects. Investigations of the nicotine discriminative stimulus complex have contributed to our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee0a59c2e8996ad876c14d7e67dd8f2
https://doi.org/10.1007/978-3-540-69248-5_11
https://doi.org/10.1007/978-3-540-69248-5_11
