Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Janice S. Valletta"'
Autor:
Damien Colas, Janice S. Valletta, Ryoko Takimoto-Kimura, Seiji Nishino, Nobuhiro Fujiki, William C. Mobley, Emmanuel Mignot
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 1, Pp 1-7 (2008)
Down syndrome is characterized by a host of behavioral abnormalities including sleep disturbances. Sleep and EEG was studied at the age of 3 months in two mouse models of the condition, Ts65Dn and Ts1Cje, carrying one extra copy of partially overlapp
Externí odkaz:
https://doaj.org/article/7818cf84556d47658b6aac984ae481d1
Autor:
Pavel V Belichenko, Rime Madani, Lorianne Rey-Bellet, Maria Pihlgren, Ann Becker, Adeline Plassard, Stephanie Vuillermot, Valérie Giriens, Rachel L Nosheny, Alexander M Kleschevnikov, Janice S Valletta, Sara K S Bengtsson, Gordon R Linke, Michael T Maloney, David T Hickman, Pedro Reis, Anne Granet, Dorin Mlaki, Maria Pilar Lopez-Deber, Long Do, Nishant Singhal, Eliezer Masliah, Matthew L Pearn, Andrea Pfeifer, Andreas Muhs, William C Mobley
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)
In Down syndrome (DS) or trisomy of chromosome 21, the β-amyloid (Aβ) peptide product of the amyloid precursor protein (APP) is present in excess. Evidence points to increased APP gene dose and Aβ as playing a critical role in cognitive difficulti
Externí odkaz:
https://doaj.org/article/e6e5615e619c41a0ad64eafb049c71c7
Autor:
Ann Becker, Lorianne Rey-Bellet, Andrea Pfeifer, Michael T. Maloney, Pavel V. Belichenko, Anne Granet, Dorin Mlaki, Valérie Giriens, Sara K. Bengtsson, David T. Hickman, Andreas Muhs, Rime Madani, Adeline Plassard, Nishant Singhal, Rachel L. Nosheny, Maria Pihlgren, Long Do, Stephanie Vuillermot, Gordon R. Linke, Matthew L. Pearn, Janice S. Valletta, William C. Mobley, Pedro Reis, María Pilar López-Deber, Alexander M. Kleschevnikov, Eliezer Masliah
Publikováno v:
PLoS ONE
PloS one, vol 11, iss 3
PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)
PloS one, vol 11, iss 3
PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)
In Down syndrome (DS) or trisomy of chromosome 21, the β-amyloid (Aβ) peptide product of the amyloid precursor protein (APP) is present in excess. Evidence points to increased APP gene dose and Aβ as playing a critical role in cognitive difficulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfba69d0dfcfb75e94cc602c199ebe4
http://europepmc.org/articles/PMC4811554
http://europepmc.org/articles/PMC4811554
Autor:
Ryoko Takimoto-Kimura, Janice S. Valletta, Damien Colas, Emmanuel Mignot, William C. Mobley, Seiji Nishino, Nobuhiro Fujiki
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 1, Pp 1-7 (2008)
Down syndrome is characterized by a host of behavioral abnormalities including sleep disturbances. Sleep and EEG was studied at the age of 3 months in two mouse models of the condition, Ts65Dn and Ts1Cje, carrying one extra copy of partially overlapp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca21482870a1cd3547c4d1d0473ac33
https://doi.org/10.1016/j.nbd.2007.07.014
https://doi.org/10.1016/j.nbd.2007.07.014
Autor:
Stephen J. Hunt, William C. Mobley, Jean-Dominique Delcroix, Janice S. Valletta, Chengbiao Wu, Anthony S. Kowal
Publikováno v:
Neuron. 39(1):69-84
Target-derived NGF promotes the phenotypic maintenance of mature dorsal root ganglion (DRG) nociceptive neurons. Here, we provide in vivo and in vitro evidence for the presence within DRG neurons of endosomes containing NGF, activated TrkA, and signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa426778f0f501cda3a6922237215308
Publikováno v:
Journal of Neurochemistry. 65:1146-1156
TrkA is a receptor tyrosine kinase for nerve growth factor (NGF). Recent studies indicate that NGF regulates not only activation of trkA kinase but also expression of the trkA gene. To further define NGF actions on trkA, we examined binding and signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f709b5b61fffac1108fc0cfbdd5bac
https://doi.org/10.1046/j.1471-4159.1995.65031146.x
https://doi.org/10.1046/j.1471-4159.1995.65031146.x
Publikováno v:
Neuron. 32:801-814
The target-derived neurotrophic factor "nerve growth factor" (NGF) signals through TrkA to promote the survival, differentiation, and maintenance of neurons. How the NGF signal in axon terminals is conveyed to the cell body is unknown. The "signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b871a76873579d608429c43c6f532a
https://doi.org/10.1016/s0896-6273(01)00526-8
https://doi.org/10.1016/s0896-6273(01)00526-8
Autor:
Louis F. Reichardt, Ella R. Vining, Paul S. Mischel, Shane G. Smith, Janice S. Valletta, William C. Mobley
Publikováno v:
Journal of Biological Chemistry. 276:11294-11301
The TrkA receptor is activated primarily by nerve growth factor (NGF), but it can also be activated by high concentrations of neurotrophin 3 (NT-3). The pan-neurotrophin receptor p75(NTR) strongly inhibits activation of TrkA by NT-3 but not by NGF. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee7226619e56e5da29bb9ff79b3a3cd
https://doi.org/10.1074/jbc.m005132200
https://doi.org/10.1074/jbc.m005132200
Autor:
Kimberly S. Topp, Nigel W. Bunnett, Eric C. Beattie, Jie Zhou, Eric C. Yuen, Deborah E. Hall, Mark L. Grimes, Jennifer H. LaVail, William C. Mobley, Janice S. Valletta
Publikováno v:
The Journal of Neuroscience. 16:7950-7964
The survival, differentiation, and maintenance of responsive neurons are regulated by nerve growth factor (NGF), which is secreted by the target and interacts with receptors on the axon tip. It is uncertain how the NGF signal is communicated retrogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a6660c2a9819cda2e1e8adad17f786
https://doi.org/10.1523/jneurosci.16-24-07950.1996
https://doi.org/10.1523/jneurosci.16-24-07950.1996
Autor:
Ryoko Takimoto-Kimura, Alexander M. Kleschevnikov, Ahmad Salehi, Mehrdad Shamloo, J. Laguna, Damien Colas, Mehrdad Faizi, Janice S. Valletta, Paul S. Aisen, William C. Mobley, Steven L. Wagner
Publikováno v:
Science translational medicine. 1(7)
Down syndrome (trisomy 21) is the most common cause of mental retardation in children and leads to marked deficits in contextual learning and memory. In rodents, these tasks require the hippocampus and are mediated by several inputs, particularly tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9250c7b993e649c0273faa745cba318
https://pubmed.ncbi.nlm.nih.gov/20368181
https://pubmed.ncbi.nlm.nih.gov/20368181