Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Janice Nickson"'
Autor:
Guenter Daxenbichler, Rachel A. Craven, Geoffrey Hall, Michael Hubalek, Steve Rayner, Richard Hutson, David Jackson, Benjamin Dieplinger, Rosamonde E. Banks, Janice Nickson, Nafisa Wilkinson, Joanne L. Hartley, Paul Lueth, Timothy J. Perren, Colin Johnston, Hans Dieplinger, Ina Graze, Robert Tonge, Peter Selby, Sean Kehoe
Publikováno v:
Clinical Cancer Research. 13:7370-7379
Purpose: To discover and validate serum glycoprotein biomarkers in ovarian cancer using proteomic-based approaches. Experimental Design: Serum samples from a “discovery set” of 20 patients with ovarian cancer or benign ovarian cysts or healthy vo
Autor:
Jonathan D. Mills, Mattias Rantalainen, Olaf Beckonert, Rachel Rowlinson, Ian D. Wilson, Steve Rayner, Olivier Cloarec, Robert Tonge, Johan Trygg, David A. Jackson, Robert W. Wilkinson, Elaine Holmes, Janice Nickson, Jeremy K. Nicholson
Publikováno v:
Journal of Proteome Research. 5:2642-2655
A novel statistically integrated proteometabonomic method has been developed and applied to a human tumor xenograft mouse model of prostate cancer. Parallel 2D-DIGE proteomic and 1H NMR metabolic profile data were collected on blood plasma from mice
Autor:
Ian D. Wilson, Rachel Rowlinson, Janice Nickson, Cassie K. Eaton, David Jackson, Robert W. Wilkinson, Robert Tonge, Jonathan D. Mills
Publikováno v:
PROTEOMICS. 6:3901-3908
Clinical studies often produce fresh tissue samples, which ideally should be immediately snap frozen for storage and subsequent analysis. However, this is often not practically possible, and there is inevitably a time period during which the sample i
Autor:
Rachel Rowlinson, Andrew Craig, Robert Tonge, David A. Jackson, Ian D. Wilson, James E. Sidaway, Janice Nickson, Jeremy K. Nicholson, Terry C. Orton, Elaine Holmes
Publikováno v:
Journal of Proteome Research. 5:1586-1601
Administration of high doses of the histamine antagonist methapyrilene to rats causes periportal liver necrosis. The mechanism of toxicity is ill-defined and here we have utilized an integrated systems approach to understanding the toxic mechanisms b
Publikováno v:
PROTEOMICS. 5:2315-2318
There is an increasing interest in analysing the human urinary proteome in the search for biomarkers. However, despite the ease of its collection, urine is a difficult fluid to analyse by two-dimensional polyacrylamide gel electrophoresis (2-D PAGE)
Autor:
Janice Nickson, Robert P. Tonge, Rachel Rowlinson, Joanne Shaw, Alison Claire Sweet, Karen Williams, Tim Stone
Publikováno v:
Proteomics. 3(7)
Two-dimensional difference gel electrophoresis (2-D DIGE) enables an increased confidence in detection of protein differences. However, due to the nature of the minimal labelling where only approximately 5% of a given protein is labelled, spots canno
Autor:
Martin Kussmann, Pierre-Alain Binz, Kathryn Resing, Akira Tsugita, Janice Nickson, David M Horn, Rong Zeng, Robert Barkovich, Roberto Raso, Kathryn S. Lilley, Chris F. Taylor, Randall K. Julian, Dieter Müller, Scott D. Patterson, Eric W. Deutsch, Thomas A. Neubert, Andreas Huhmer, Sean L. Seymour, Matthias Mann, Ioannis Xenarios, Marcus Macht, Michel Affolter, Ruedi Aebersold
Publikováno v:
Nature Biotechnology. 26:860-861
Autor:
Jill E. Hunter, Sabrina Giavara, Alan Lau, Carsten Lueck, Richard Allum, John E. Prime, Rachel Rowlinson, Janice Nickson, Mark J. O'Connor, Louise Unwin
Publikováno v:
Molecular Cancer Therapeutics. 8:A119-A119
Background: The oral PARP inhibitor olaparib (AZD2281, KU-0059436) has been shown to have single agent clinical activity in tumors from patients with hereditary BRCA mutations (Fong et al., 2009). Pre-clinical studies have also shown sensitivity to P
Autor:
Joanne Shaw, Rachel Rowlinson, Janice Nickson, Tim Stone, Alison Sweet, Karen Williams, Robert Tonge
Publikováno v:
Proteomics; Jul2003, Vol. 3 Issue 7, p1181-1195, 15p