Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Janice M.W. Taylor"'
Publikováno v:
World Journal of Cardiology
Accumulation of macrophage “foam” cells, laden with cholesterol and cholesteryl ester, within the intima of large arteries, is a hallmark of early “fatty streak” lesions which can progress to complex, multicellular atheromatous plaques, invol
Publikováno v:
Clinical Science. 127:603-613
The aim of the present study was to establish mitochondrial cholesterol trafficking 18 kDa translocator protein (TSPO) as a potential therapeutic target, capable of increasing macrophage cholesterol efflux to (apo)lipoprotein acceptors. Expression an
Publikováno v:
Clinical Science. 124:509-515
Cholesterol trafficking from the outer to the cholesterol-poor inner mitochondrial membrane requires energized, polarized and actively respiring mitochondria, mediated by a highly regulated multimeric (140–200 kDa) protein complex comprising StAR (
Publikováno v:
Clinical Science
Clinical Science, Portland Press, 2010, 119 (7), pp.265-272. ⟨10.1042/CS20100266⟩
Clinical Science (London, England : 1979)
Clinical Science, Portland Press, 2010, 119 (7), pp.265-272. ⟨10.1042/CS20100266⟩
Clinical Science (London, England : 1979)
Dysregulated macrophage cholesterol homoeostasis lies at the heart of early and developing atheroma, and removal of excess cholesterol from macrophage foam cells, by efficient transport mechanisms, is central to stabilization and regression of athero
Publikováno v:
Cardiovascular Research. 86:526-534
Aims In this study, we investigated the impact of enhancing cholesterol delivery to mitochondrial sterol 27-hydroxylase, via steroidogenic acute regulatory protein (StAR), on the expression of genes involved in macrophage cholesterol homeostasis and
Publikováno v:
FEBS Letters. 581:4877-4883
Human resistin, found within atheroma, exerts inflammatory, angiogenic and proliferative effects in vascular cells and may predict coronary events. Here, we investigate mechanisms by which resistin contributes to macrophage ‘foam cell’ formation.
Autor:
Niall A. Logan, Janice M.W. Taylor, Le H. Duc, Tran Cat Dong, Simon M. Cutting, Alastair D. Sutherland
Publikováno v:
International Journal of Food Microbiology. 102:245-251
A commercial product for infants containing cereal mixed with dried infant formula was diagnosed as producing rapid projectile vomiting in two infants. Analysis of multiple samples of the cereal product revealed significant contamination with two spo
Publikováno v:
Cholesterol Transporters of the START Domain Protein Family in Health and Disease ISBN: 9781493911110
Atherosclerosis, the primary cause of coronary heart disease, is characterised by a low-grade unresolved inflammation associated with accumulation of cholesterol and cholesteryl-ester laden macrophages within the intima of the vessel wall. Steroidoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38861e2b11295f922484d5054814ad79
https://doi.org/10.1007/978-1-4939-1112-7_5
https://doi.org/10.1007/978-1-4939-1112-7_5
Publikováno v:
FEMS microbiology letters. 242(2)
Strains of Bacillus cereus can produce a heat-stable toxin (cereulide). In this study, 101 Bacillus strains representing 7 Bacillus species were tested for production of heat-stable toxins. Strains of B. megaterium, B. firmus and B. simplex were foun
Publikováno v:
FEBS Letters. (7):1147-1153
The STARD1 subfamily of ‘START’ lipid trafficking proteins can reduce macrophage lipid content and inflammatory status (STARD1; StAR), and traffic cholesterol from endosomes (STARD3/MLN64). During macrophage differentiation, STARD1 mRNA and prote