Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Janice M. Huss"'
Autor:
Rekha Balakrishnan, Pablo A. Garcia, Rajakrishnan Veluthakal, Janice M. Huss, Joseph M. Hoolachan, Debbie C. Thurmond
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1658 (2023)
The p21-activated kinase 1 (PAK1) is required for insulin-stimulated glucose uptake in skeletal muscle cells. However, whether PAK1 regulates skeletal muscle mitochondrial function, which is a central determinant of insulin sensitivity, is unknown. H
Externí odkaz:
https://doaj.org/article/fa5f47e8f89f4b80a08ae9cc988484c8
Autor:
Karla E. Merz, Jinhee Hwang, Chunxue Zhou, Rajakrishnan Veluthakal, Erika M. McCown, Angelica Hamilton, Eunjin Oh, Wenting Dai, Patrick T. Fueger, Lei Jiang, Janice. M. Huss, Debbie C. Thurmond
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
STX4 is a regulator of the glucose transporter GLUT4 vesicle fusion at the plasma membrane in skeletal muscle. Here, the authors show that skeletal muscle-specific STX4 enrichment reverses established insulin resistance and improves mitochondrial fun
Externí odkaz:
https://doaj.org/article/86d199eac4974e6cb433219b443e6627
Autor:
Cyrielle Billon, Sadichha Sitaula, Subhashis Banerjee, Ryan Welch, Bahaa Elgendy, Lamees Hegazy, Tae Gyu Oh, Melissa Kazantzis, Arindam Chatterjee, John Chrivia, Matthew E. Hayes, Weiyi Xu, Angelica Hamilton, Janice M. Huss, Lilei Zhang, John K. Walker, Michael Downes, Ronald M. Evans, Thomas P. Burris
Publikováno v:
ACS Chemical Biology. 18:756-771
Autor:
Janice M. Huss, Susan E. Kane, Jamil Momand, Markus Kalkum, Teresa Hong, Shuhui Geng, Angelica Hamilton, Gal Lenz
Table S1. Co-occurrence analysis of PPP1R1B and IGF-1R transcripts Table S2. Hazard ratios associated with PPP1R1B and IGF-1R expression Table S3. Multivariate analysis of PPP1R1B and IGF-1R with HER2 for OS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e53be5ad4de6c78bd01e35cecf8f3bf
https://doi.org/10.1158/1078-0432.22464455.v1
https://doi.org/10.1158/1078-0432.22464455.v1
Autor:
Janice M. Huss, Susan E. Kane, Jamil Momand, Markus Kalkum, Teresa Hong, Shuhui Geng, Angelica Hamilton, Gal Lenz
Figure S1. Protein levels of PPP1R1B and IGF-1R. Figure S2. Comparison of respiration rates in SK-BR-3 parental and derived cell lines. Figure S3. siRNA knockdown of IGF-1R and IR. Figure S4. The effect of recombinant t-Darpp on oxygen consumption ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9635ebb041d768c87abc8b0840f1bb
https://doi.org/10.1158/1078-0432.22464461.v1
https://doi.org/10.1158/1078-0432.22464461.v1
Autor:
Janice M. Huss, Susan E. Kane, Jamil Momand, Markus Kalkum, Teresa Hong, Shuhui Geng, Angelica Hamilton, Gal Lenz
Purpose: Increased glycolysis and glucose dependence is a hallmark of malignancy that enables tumors to maximize cell proliferation. In HER2+ cancers, an increase in glycolytic capacity is associated with trastuzumab resistance. IGF-1R activation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce98ba32c1e12ae330c21ef4bed3b0a
https://doi.org/10.1158/1078-0432.c.6525725
https://doi.org/10.1158/1078-0432.c.6525725
Autor:
Cyrielle Billon, Sadichha Sitaula, Subhashis Banerjee, Ryan Welch, Bahaa Elgendy, Lamees Hegazy, Tae Gyu Oh, Melissa Kazantzis, Arindam Chatterjee, John Chrivia, Matthew E. Hayes, Weiyi Xu, Angelica Hamilton, Janice M. Huss, Lilei Zhang, John K Walker, Michael Downes, Ronald M. Evans, Thomas P. Burris
Repetitive physical exercise induces physiological adaptations in skeletal muscle that improves exercise performance and is effective for the prevention and treatment of several diseases. Here we report the identification of a synthetic agonist for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2a723472befde6dde4f64fceb0b1b1f
https://doi.org/10.1101/2022.10.05.510974
https://doi.org/10.1101/2022.10.05.510974
Autor:
Zhen Bouman Chen, Xiwei Wu, Linda Lanting, Maryam Abdollahi, Mitsuo Kato, Rama Natarajan, Zhuo Chen, Patrick T. Fueger, Jinhui Wang, Feng-Mao Lin, Ragadeepthi Tunduguru, Walter Tsark, David C. Chan, Mei Wang, Janice M. Huss
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Communications Biology
Am J Physiol Renal Physiol
Communications Biology
Am J Physiol Renal Physiol
Diabetic kidney disease (DKD) is a major complication of diabetes. Expression of members of the microRNA (miRNA) miR-379 cluster is increased in DKD. miR-379, the most upstream 5′-miRNA in the cluster, functions in endoplasmic reticulum (ER) stress
Autor:
Philipp E. Scherer, Aimin Li, Hu Zhao, Jiayi Tan, Lei Jiang, Mengle Shao, Xiwei Wu, Qiong A. Wang, Marcia M. Miller, Brian Armstrong, Wenting Dai, Yong Liu, Yi Zhu, Janice M. Huss, Min Jee Jang, Viviana Gradinaru, Zhuo Li, Leonard Medrano, Anying Song, Tinglu Ning
Publikováno v:
Journal of Clinical Investigation. 130:247-257
Brown adipose tissue (BAT), as the main site of adaptive thermogenesis, exerts beneficial metabolic effects on obesity and insulin resistance. BAT has been previously assumed to contain a homogeneous population of brown adipocytes. Utilizing multiple