Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Janice M Reimer"'
Publikováno v:
eLife, Vol 12 (2023)
The lissencephaly 1 protein, LIS1, is mutated in type-1 lissencephaly and is a key regulator of cytoplasmic dynein-1. At a molecular level, current models propose that LIS1 activates dynein by relieving its autoinhibited form. Previously we reported
Externí odkaz:
https://doaj.org/article/4bd943e978794483b3f735335788a310
Autor:
John P Gillies, Janice M Reimer, Eva P Karasmanis, Indrajit Lahiri, Zaw Min Htet, Andres E Leschziner, Samara L Reck-Peterson
Publikováno v:
eLife, Vol 11 (2022)
The lissencephaly 1 gene, LIS1, is mutated in patients with the neurodevelopmental disease lissencephaly. The Lis1 protein is conserved from fungi to mammals and is a key regulator of cytoplasmic dynein-1, the major minus-end-directed microtubule mot
Externí odkaz:
https://doaj.org/article/0c338fe5a65746bb99102d46fccf8b0d
Autor:
Janice M. Reimer, Andrea M. Dickey, Yu Xuan Lin, Robert G. Abrisch, Sebastian Mathea, Deep Chatterjee, Elizabeth J. Fay, Stefan Knapp, Matthew D. Daugherty, Samara L. Reck-Peterson, Andres E. Leschziner
Leucine Rich Repeat Kinase 1 and 2 (LRRK1 and LRRK2) are homologs in the ROCO family of proteins in humans. Despite their shared domain architecture and involvement in intracellular trafficking, their disease associations are strikingly different: LR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc87af7022e01bc85212e35409e1f071
https://doi.org/10.1101/2022.11.22.517582
https://doi.org/10.1101/2022.11.22.517582
Autor:
Eva P. Karasmanis, Janice M. Reimer, Agnieszka A. Kendrick, Jennifer A. Rodriguez, Joey B. Truong, Indrajit Lahiri, Samara L. Reck-Peterson, Andres E. Leschziner
Cytoplasmic dynein-1 transports many intracellular cargos towards microtubule minus ends. Dynein is autoinhibited and undergoes conformational changes to form an active complex, consisting of one or two dynein dimers, the dynactin complex and activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff227b7a0395637c5862ac9cf27fc746
https://doi.org/10.1101/2022.10.10.511666
https://doi.org/10.1101/2022.10.10.511666
Autor:
Tsutomu, Arakawa, Masao, Tokunaga, Yoshiko, Kita, Takako, Niikura, Richard W, Baker, Janice M, Reimer, Andres E, Leschziner
Publikováno v:
The protein journal. 40(6)
Difference circular dichroism (CD) spectroscopy was used here to characterize changes in structure of flexible peptides upon altering their environments. Environmental changes were introduced by binding to a large target structure, temperature shift
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3858707de8fecdf714cfabf1f767fd2
https://pubmed.ncbi.nlm.nih.gov/34709521
https://pubmed.ncbi.nlm.nih.gov/34709521
Autor:
John P Gillies, Janice M Reimer, Eva P Karasmanis, Indrajit Lahiri, Zaw Min Htet, Andres E Leschziner, Samara L Reck-Peterson
Publikováno v:
eLife, Vol 11 (2022)
The lissencephaly 1 gene, LIS1, is mutated in patients with the neurodevelopmental disease lissencephaly. The Lis1 protein is conserved from fungi to mammals and is a key regulator of cytoplasmic dynein-1, the major minus-end-directed microtubule mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fabca1f94be8bc373cad4a42fe72cf
https://pubmed.ncbi.nlm.nih.gov/34994688
https://pubmed.ncbi.nlm.nih.gov/34994688