Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Janice M Pluth"'
Autor:
Minli Wang, Megumi Hada, Janapriya Saha, Deepa M Sridharan, Janice M Pluth, Francis A Cucinotta
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41249 (2012)
Proton radiotherapy has gained more favor among oncologists as a treatment option for localized and deep-seated tumors. In addition, protons are a major constituent of the space radiation astronauts receive during space flights. The potential for the
Externí odkaz:
https://doaj.org/article/2d7bf8c08cd148ef8b86cffca780d248
Autor:
Latisha Carswell, Deepa M. Sridharan, Lung-Chang Chien, Wataru Hirose, Véronique Giroux, Hiroshi Nakagawa, Janice M. Pluth
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 519 (2024)
Esophageal squamous cell carcinoma (ESCC) is a deadly consequence of radiation exposure to the esophagus. ESCC arises from esophageal epithelial cells that undergo malignant transformation and features a perturbed squamous cell differentiation progra
Externí odkaz:
https://doaj.org/article/894b910b6b1c4ad7abfc8fb63886b7c5
Autor:
Jennifer To, Janice M. Pluth, Brandi Wiedmeyer, Hidetoshi Mori, Antoine M. Snijders, Lung Chang Chien, Deepa M. Sridharan
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 109:1521-1532
Purpose Computed tomographic (CT) scans in adolescents have increased dramatically in recent years. However, the effects of cumulative low-dose exposures on the development of radiation sensitive organs, such as the mammary gland, is unknown. The pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b6ebb7f20326e6f3fa144cba4127e2
https://doi.org/10.1016/j.ijrobp.2020.11.039
https://doi.org/10.1016/j.ijrobp.2020.11.039
Autor:
Ronald Benjamin, Atoshi Banerjee, Xiaogang Wu, Corey Geurink, Lindsay Buczek, Danielle Eames, Sara G. Trimidal, Janice M. Pluth, Martin R. Schiller
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 593, p 593 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 593
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 593
International Journal of Molecular Sciences
Double-strand breaks (DSB) are one of the most lethal forms of DNA damage that, if left unrepaired, can lead to genomic instability, cellular transformation, and cell death. In this work, we examined how repair of transcription activator-like effecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a736576cc6b0fb69cf55707ecbf2fc
https://www.mdpi.com/1422-0067/23/2/593
https://www.mdpi.com/1422-0067/23/2/593
Autor:
Janice M. Pluth, Chris Wang, Shiena Enerio, Mark A. LaBarge, Deepa M. Sridharan, Martha R. Stampfer
Publikováno v:
Sridharan, DM; Enerio, S; Wang, C; LaBarge, MA; Stampfer, MR; & Pluth, JM. (2019). Genetic variation and radiation quality impact cancer promoting cellular phenotypes in response to HZE exposure. Life Sciences in Space Research, 20, 101-112. doi: 10.1016/j.lssr.2018.10.002. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/5gb776b6
© 2018 The Committee on Space Research (COSPAR) There exists a wide degree of genetic variation within the normal human population which includes disease free individuals with heterozygote defects in major DNA repair genes. A lack of understanding o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c9303564a5478bd96d2c971c553771
https://escholarship.org/uc/item/5gb776b6
https://escholarship.org/uc/item/5gb776b6
Autor:
Jan H.J. Hoeijmakers, Priscilla K. Cooper, Brian Shih, Ann C. Parplys, Miaw Sheue Tsai, Torsten Groesser, Kelly S. Trego, Janice M. Pluth, Ayesu Hlaing, Michael R. Nelson, Weixing Zhao, Patrick Sung, Claudia Wiese, Albert R. Davalos, Björn Rydberg, Judith Campisi
Publikováno v:
Trego, K S, Groesser, T, Davalos, A R, Parplys, A C, Zhao, W, Nelson, M R, Hlaing, A, Shih, B, Rydberg, B, Pluth, J M, Tsai, M-S, Hoeijmakers, J H J, Sung, P, Wiese, C, Campisi, J & Cooper, P K 2016, ' Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability ', Molecular Cell, vol. 61, pp. 535–546 . https://doi.org/10.1016/j.molcel.2015.12.026
Molecular cell, vol 61, iss 4
Trego, KS; Groesser, T; Davalos, AR; Parplys, AC; Zhao, W; Nelson, MR; et al.(2016). Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability. Molecular Cell, 61(4), 535-546. doi: 10.1016/j.molcel.2015.12.026. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/2618t9h0
Molecular Cell, 61(4), 535-546. Cell Press
Molecular cell, vol 61, iss 4
Trego, KS; Groesser, T; Davalos, AR; Parplys, AC; Zhao, W; Nelson, MR; et al.(2016). Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability. Molecular Cell, 61(4), 535-546. doi: 10.1016/j.molcel.2015.12.026. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/2618t9h0
Molecular Cell, 61(4), 535-546. Cell Press
© 2016 Elsevier Inc. XPG is a structure-specific endonuclease required for nucleotide excision repair, and incision-defective XPG mutations cause the skin cancer-prone syndrome xeroderma pigmentosum. Truncating mutations instead cause the neurodevel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcfec2d212a7de1b61ea0d9e00e48d8
https://doi.org/10.1016/j.molcel.2015.12.026
https://doi.org/10.1016/j.molcel.2015.12.026
Autor:
Megumi Hada, Jennifer A. Anderson, Minli Wang, Francis A. Cucinotta, Peter O'Neill, Janapriya Saha, Janice M. Pluth
Publikováno v:
Nucleic Acids Research
Cellular damage from ionizing radiation (IR) is in part due to DNA damage and reactive oxygen species, which activate DNA damage response (DDR) and cytokine signaling pathways, including the ataxia telangiectasia mutated (ATM) and transforming growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6019fbdb6074137634f1ed2dc7eb519b
https://doi.org/10.1093/nar/gks1038
https://doi.org/10.1093/nar/gks1038
Autor:
Janice M. Pluth, Francis A. Cucinotta, Kerry George, Lori J. Jackson, Tetsuya Kawata, Todd Elliott, Megumi Hada
Publikováno v:
Radiation Research. 171:752-763
We studied the effects of DNA double-strand break (DSB) repair deficiencies on chromosomal aberration frequency using low doses (1 Gy) of gamma rays and high-energy iron ions (LET = 151 keV/microm). Chromosomal aberrations were measured using the flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14cb5ddecb1e261e41d8a74de4f3df2
https://doi.org/10.1667/rr1680.1
https://doi.org/10.1667/rr1680.1
Publikováno v:
Radiation Research. 170:353-364
To determine whether the physical differences between high- and low-LET radiation are reflected in the biological responses of exposed cells, we detailed phospho-protein profiles of three proteins functional in radiation repair and signal transductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc28c184d4f5b144b8463a960042c060
https://doi.org/10.1667/rr1354.1
https://doi.org/10.1667/rr1354.1
Publikováno v:
Radiation Research. 169:214-222
We developed a biochemical kinetics approach to describe the repair of double-strand breaks (DSBs) produced by low-LET radiation by modeling molecular events associated with non-homologous end joining (NHEJ). A system of coupled nonlinear ordinary di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26821683068e8095eed51e7f68d99b41
https://doi.org/10.1667/rr1035.1
https://doi.org/10.1667/rr1035.1