Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Janice L. Shaw"'
Autor:
Roderick C. Slieker, Louise A. Donnelly, Elina Akalestou, Livia Lopez-Noriega, Rana Melhem, Ayşim Güneş, Frederic Abou Azar, Alexander Efanov, Eleni Georgiadou, Hermine Muniangi-Muhitu, Mahsa Sheikh, Giuseppe N. Giordano, Mikael Åkerlund, Emma Ahlqvist, Ashfaq Ali, Karina Banasik, Søren Brunak, Marko Barovic, Gerard A. Bouland, Frédéric Burdet, Mickaël Canouil, Iulian Dragan, Petra J. M. Elders, Celine Fernandez, Andreas Festa, Hugo Fitipaldi, Phillippe Froguel, Valborg Gudmundsdottir, Vilmundur Gudnason, Mathias J. Gerl, Amber A. van der Heijden, Lori L. Jennings, Michael K. Hansen, Min Kim, Isabelle Leclerc, Christian Klose, Dmitry Kuznetsov, Dina Mansour Aly, Florence Mehl, Diana Marek, Olle Melander, Anne Niknejad, Filip Ottosson, Imre Pavo, Kevin Duffin, Samreen K. Syed, Janice L. Shaw, Over Cabrera, Timothy J. Pullen, Kai Simons, Michele Solimena, Tommi Suvitaival, Asger Wretlind, Peter Rossing, Valeriya Lyssenko, Cristina Legido Quigley, Leif Groop, Bernard Thorens, Paul W. Franks, Gareth E. Lim, Jennifer Estall, Mark Ibberson, Joline W. J. Beulens, Leen M ’t Hart, Ewan R. Pearson, Guy A. Rutter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract We identify biomarkers for disease progression in three type 2 diabetes cohorts encompassing 2,973 individuals across three molecular classes, metabolites, lipids and proteins. Homocitrulline, isoleucine and 2-aminoadipic acid, eight triacyl
Externí odkaz:
https://doaj.org/article/8eb84b4a486246dfb262ac9be25f0911
Episodic β-cell death and dedifferentiation during diet-induced obesity and dysglycemia in male mice
Autor:
Farooq Syed, Thomas B. Farb, Sarah A. Tersey, Kieren J. Mather, Janice L. Shaw, Kara S. Orr, Raghavendra G. Mirmira, Esther M. Levasseur, Krister Bokvist, Jennifer Nelson
Loss of functional islet β-cell mass through cellular death or dedifferentiation is thought to lead to dysglycemia during the progression from obesity to type 2 diabetes. To assess these processes in a mouse model of obesity, we performed measures o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d876ea3c31aa81b3bc4f90e1732a0293
https://europepmc.org/articles/PMC6181632/
https://europepmc.org/articles/PMC6181632/
Publikováno v:
Journal of Chemical Neuroanatomy. 26:179-193
Neuropeptide Y, one of the most abundant brain peptides, has been found to modulate several important biological functions via a family of G-protein coupled receptors. To investigate the localization of functional NPY receptor subtypes in the rat bra
Autor:
Annika Thorsell, Markus Heilig, Andrea Cippitelli, Camilla Karlsson, Janice L. Shaw, Donald R. Gehlert
Publikováno v:
Psychopharmacology. 211(4)
Melanin-concentrating hormone (MCH) is involved in regulation of appetitive behaviors as well as emotional reactivity and reward, behavioral domains relevant to alcohol addiction.We evaluated the effects of the non-peptide MCH1 receptor antagonist, G
Autor:
Janice L. Shaw, Donald R. Gehlert
Publikováno v:
Peptides. 28(2)
The brain neuropeptide Neuropeptide Y (NPY) is an important modulator of a number of centrally mediated processes including feeding, anxiety-like behaviors, blood pressure and others. NPY produces its effects through at least four functional G-protei
Publikováno v:
Neuropeptides. 40(2)
The peptide, nociceptin, was discovered as the endogenous ligand for the opioid-like receptor, ORL1. Since its discovery, this peptide has been shown to modulate the perception of pain, modulate feeding and produce behavioral effects in rodent models