Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Janice L Holton"'
Autor:
Renata Siciliani Scalco, Sherryl Chatfield, Richard Godfrey, Jatin Pattni, Charlotte Ellerton, Andrea Beggs, Stefen Brady, Andrew Wakelin, Janice L Holton, Ros Quinlivan
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 72, Iss 7, Pp 538-541 (2014)
McArdle disease is the most common of the glycogen storage diseases. Onset of symptoms is usually in childhood with muscle pain and restricted exercise capacity. Signs and symptoms are often ignored in children or put down to ‘growing pains’ and
Externí odkaz:
https://doaj.org/article/081021cb70b947bca35c95ce216eca8d
Autor:
Lucia V Schottlaender, Conceição Bettencourt, Aoife P Kiely, Annapurna Chalasani, Viruna Neergheen, Janice L Holton, Iain Hargreaves, Henry Houlden
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149557 (2016)
BACKGROUND:The objective of this study was to evaluate whether the levels of coenzyme Q10 (CoQ10) in brain tissue of multiple system atrophy (MSA) patients differ from those in elderly controls and in patients with other neurodegenerative diseases. M
Externí odkaz:
https://doaj.org/article/2f767606f9b74ae0917b38373a49e81f
Autor:
Sanjeev Rajakulendran, Robert D S Pitceathly, Jan-Willem Taanman, Harry Costello, Mary G Sweeney, Cathy E Woodward, Zane Jaunmuktane, Janice L Holton, Thomas S Jacques, Brian N Harding, Carl Fratter, Michael G Hanna, Shamima Rahman
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145500 (2016)
Mutations in the nuclear gene POLG (encoding the catalytic subunit of DNA polymerase gamma) are an important cause of mitochondrial disease. The most common POLG mutation, A467T, appears to exhibit considerable phenotypic heterogeneity. The mechanism
Externí odkaz:
https://doaj.org/article/ec6375b1818241cab0f1ce4c29b4eb0c
Autor:
Melek Firat Altay, Senthil T. Kumar, Johannes Burtscher, Somanath Jagannath, Catherine Strand, Yasuo Miki, Laura Parkkinen, Janice L. Holton, Hilal A. Lashuel
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-21 (2023)
Abstract The abnormal aggregation and accumulation of alpha-synuclein (aSyn) in the brain is a defining hallmark of synucleinopathies. Various aSyn conformations and post-translationally modified forms accumulate in pathological inclusions and vary i
Externí odkaz:
https://doaj.org/article/75e3ac5b75ef4930b6ce1a22c6cbcc54
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Alpha-synuclein (aSyn) is a pre-synaptic monomeric protein that can form aggregates in neurons in Parkinson’s disease (PD), Parkinson’s disease with dementia (PDD) and dementia with Lewy bodies (DLB), and in oligodendrocytes in multiple
Externí odkaz:
https://doaj.org/article/6103c9cd4bc2417fb7e51710ce817149
Autor:
Melek Firat Altay, Senthil T. Kumar, Johannes Burtscher, Somanath Jagannath, Catherine Strand, Yasuo Miki, Laura Parkkinen, Janice L. Holton, Hilal A. Lashuel
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/2c0f9e4aea4c4551a955fc5dc5d2bcfc
Autor:
Therése Klingstedt, Bernardino Ghetti, Janice L. Holton, Helen Ling, K. Peter R. Nilsson, Michel Goedert
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Synucleinopathies [Parkinson’s disease with or without dementia, dementia with Lewy bodies and multiple system atrophy] are neurodegenerative diseases that are defined by the presence of filamentous α-synuclein inclusions. We investigated
Externí odkaz:
https://doaj.org/article/8dad256167b248d884bc6cb889998d77
Autor:
Diego Perez-Rodriguez, Maria Kalyva, Melissa Leija-Salazar, Tammaryn Lashley, Maxime Tarabichi, Viorica Chelban, Steve Gentleman, Lucia Schottlaender, Hannah Franklin, George Vasmatzis, Henry Houlden, Anthony H. V. Schapira, Thomas T. Warner, Janice L. Holton, Zane Jaunmuktane, Christos Proukakis
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-22 (2019)
Abstract Synucleinopathies are mostly sporadic neurodegenerative disorders of partly unexplained aetiology, and include Parkinson’s disease (PD) and multiple system atrophy (MSA). We have further investigated our recent finding of somatic SNCA (α-
Externí odkaz:
https://doaj.org/article/7ef14b0631654f92929d5d083479b9c2
Autor:
Agueda Rostagno, Miguel Calero, Janice L. Holton, Tamas Revesz, Tammaryn Lashley, Jorge Ghiso
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105452- (2021)
Familial British and Danish dementias (FBD and FDD) share striking neuropathological similarities with Alzheimer's disease (AD), including intraneuronal neurofibrillary tangles as well as parenchymal and vascular amyloid deposits. Multiple amyloid as
Externí odkaz:
https://doaj.org/article/54b457bb84c94036aa620a214cf29cfe
Autor:
Yasuo Miki, Conceição Bettencourt, Zane Jaunmuktane, Janice L. Holton, Thomas T. Warner, Koichi Wakabayashi
Publikováno v:
Neuropathology and Applied Neurobiology. 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b6fca12c05ebb7539c484c5b175d1bc
https://doi.org/10.1111/nan.12878
https://doi.org/10.1111/nan.12878