Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Janice J, Endsley"'
Autor:
Alex J. Holloway, Tais B. Saito, Kubra F. Naqvi, Matthew B. Huante, Xiuzhen Fan, Joshua G. Lisinicchia, Benjamin B. Gelman, Janice J. Endsley, Mark A. Endsley
Publikováno v:
Retrovirology, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract The study of HIV infection and pathogenicity in physical reservoirs requires a biologically relevant model. The human immune system (HIS) mouse is an established model of HIV infection, but defects in immune tissue reconstitution remain a ch
Externí odkaz:
https://doaj.org/article/6b210dbcdb27465b8b11fb6325b97717
Autor:
Yazmin B. Martinez-Martinez, Matthew B. Huante, Sadhana Chauhan, Kubra F. Naqvi, Preeti Bharaj, Janice J. Endsley
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Therapeutic vaccines have promise as adjunctive treatment for tuberculosis (TB) or as preventives against TB relapse. An important development challenge is the limited understanding of T helper (Th) cell roles during these stages of disease.
Externí odkaz:
https://doaj.org/article/ff8ab6f613584aa48601eb8daf6a6c81
Autor:
Sadhana Chauhan, Rebecca J. Nusbaum, Matthew B. Huante, Alex J. Holloway, Mark A. Endsley, Benjamin B. Gelman, Joshua G. Lisinicchia, Janice J. Endsley
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 9, Iss 6, p 129 (2024)
L-arginine metabolism is strongly linked with immunity to mycobacteria, primarily through the antimicrobial activity of nitric oxide (NO). The potential to modulate tuberculosis (TB) outcomes through interventions that target L-arginine pathways are
Externí odkaz:
https://doaj.org/article/fcdde219cac24a639c2dea6cb1679b64
Autor:
Megan A. Files, Kubra F. Naqvi, Tais B. Saito, Tara M. Clover, Jai S. Rudra, Janice J. Endsley
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Heterologous vaccine regimens could extend waning protection in the global population immunized with Mycobacterium bovis Bacille Calmette-Guerin (BCG). We demonstrate that pulmonary delivery of peptide nanofibers (PNFs) bearing an Ag85B CD4+
Externí odkaz:
https://doaj.org/article/74cb267c345f461e8f9ffd236df85864
Publikováno v:
Cells, Vol 12, Iss 18, p 2295 (2023)
Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) co-infection continues to pose a significant healthcare burden. HIV co-infection during TB predisposes the host to the reactivation of latent TB infection (LTBI), worsening disease conditions a
Externí odkaz:
https://doaj.org/article/a50eea363a1e4a54b1ad50c7b1e93f6f
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Development of novel immunization approaches to combat a growing list of emerging and ancient infectious agents is a global health priority. Intensive efforts over the last several decades have identified alternative approaches to improve upon tradit
Externí odkaz:
https://doaj.org/article/2391c80efb884d2597ee572461a7469b
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Humanized mice have become an important workhorse model for HIV research. Advances that enabled development of a human immune system in immune deficient mouse strains have aided new basic research in HIV pathogenesis and immune dysfunction.
Externí odkaz:
https://doaj.org/article/50758e105aea46e1b3821d4891fea15b
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract Melioidosis, caused by Burkholderia pseudomallei (Bpm), lacks a vaccine. We identify the immune correlates of protection induced by B. mallei ΔtonB Δhcp1 (CLH001) and Bpm ΔtonB Δhcp1 (PBK001) vaccines against inhalational melioidosis. Mu
Externí odkaz:
https://doaj.org/article/1ed07a95843f4f11b748cd921ed20a08
Autor:
Kubra F. Naqvi, Janice J. Endsley
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
C-type lectin receptors (CLRs) are carbohydrate binding pattern recognition receptors (PRRs) which play a central role in host recognition of pathogenic microorganisms. Signaling through CLRs displayed on antigen presenting cells dictates important i
Externí odkaz:
https://doaj.org/article/71a21b8ea6bf4c018c86ed7d89139369
Autor:
Matthew B. Huante, Tais B. Saito, Rebecca J. Nusbaum, Kubra F. Naqvi, Sadhana Chauhan, Robert L. Hunter, Jeffrey K. Actor, Jai S. Rudra, Mark A. Endsley, Joshua G. Lisinicchia, Benjamin B. Gelman, Janice J. Endsley
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Tuberculosis relapse following drug treatment of active disease is an important global public health problem due to the poorer clinical outcomes and increased risk of drug resistance development. Concurrent infection with HIV, including in those rece
Externí odkaz:
https://doaj.org/article/cd4e3d98969049a594a05d8680fa4ed0