Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Janice Hunter"'
Publikováno v:
Pediatric Pulmonology. 28:199-204
Thoracoabdominal asynchrony (TAA) and the ratio of time to peak tidal expiratory flow over total expiratory time (TME/TE) have been used to assess airway obstruction in infants and adults. We obtained these measurements using calibrated respiratory i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d032323930c18b9892cc686491554b18
https://doi.org/10.1002/(sici)1099-0496(199909)28:3<199::aid-ppul7>3.0.co
https://doi.org/10.1002/(sici)1099-0496(199909)28:3<199::aid-ppul7>3.0.co
Publikováno v:
Advanced Drug Delivery Reviews. 25:243-256
The proximal renal tubule is the major site of P-glycoprotein expression within the kidney; there is good evidence that P-glycoprotein expression is not restricted to the proximal tubule occurring in thick ascending limb and more distal segments. P-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d81dc9a532edd501b601842280c023ea
https://doi.org/10.1016/s0169-409x(97)00502-4
https://doi.org/10.1016/s0169-409x(97)00502-4
Autor:
Barry H. Hirst, Janice Hunter
Publikováno v:
Advanced Drug Delivery Reviews. 25:129-157
Oral bioavailability requires absorption of drugs across the intestinal epithelium. This may be mediated by either the paracellular and/or transcellular routes. Passive transcellular absorption requires the appropriate physicochemical properties to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::313ed6e5f24b58c694e02e0f32c20b4c
https://doi.org/10.1016/s0169-409x(97)00497-3
https://doi.org/10.1016/s0169-409x(97)00497-3
Publikováno v:
Journal of the Association of Nurses in AIDS Care. 8:41-50
Coordinating a large multicentered pediatric HIV clinical research study is particularly challenging for nurses. The cohort of patients and their families face multiple stressors, which make recruitment and compliance difficult. Additionally, when ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba9002378c9b6510c534041a51eb7b8
https://doi.org/10.1016/s1055-3290(97)80036-2
https://doi.org/10.1016/s1055-3290(97)80036-2
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1237(1):31-36
Bodipy-verapamil has been tested as a fluorescent substrate for P-glycoprotein-mediated transepithelial secretion in MDCK-C5A epithelia. Net transepithelial secretion ( J net ) of [ 3 H]vinblastine from basal-to-apical surfaces of monolayer epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c261c1c2b01a8083ab45c9e7ed2ab6c
Publikováno v:
Journal of Biological Chemistry. 268:14991-14997
The functional expression of P-glycoprotein has been studied in confluent epithelial layers of human Caco-2 cells, a polarized, highly differentiated cell line demonstrating an intestinal absorptive cell phenotype. Expression of P-glycoprotein was lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ef8925bd6bf7f0bf67159e398f8e3b
https://doi.org/10.1016/s0021-9258(18)82429-2
https://doi.org/10.1016/s0021-9258(18)82429-2
Publikováno v:
Pharmaceutical Research. 10:743-749
The hypothesis was tested that the operation of an ATP-dependent export pump localized at the apical (brush border) surface of the intestinal epithelium may limit substrate absorption kinetics. Human intestinal Caco-2 cell-layers display saturable se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5602e567463f9a9b0990d173039696bb
https://doi.org/10.1023/a:1018972102702
https://doi.org/10.1023/a:1018972102702
Publikováno v:
Biochemical and Biophysical Research Communications. 181:671-676
[ 3 H]Vinblastine transport across MDCK (renal epithelial) cell layers has been characterised. The basal-to-apical [ 3 H]vinblastine flux (J A-B ) (at 10 nM) exceeded apical-to-basal flux by 19.6 fold. Net vinblastine secretion (J B-A -J A-B )was inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b9f672dc81201d487320b66f8aa13b
https://doi.org/10.1016/0006-291x(91)91243-6
https://doi.org/10.1016/0006-291x(91)91243-6
Publikováno v:
British Journal of Cancer
P-glycoprotein expression was demonstrated in two human intestinal adenocarcinoma cell-lines (HCT-8, ileocaecal and T84, colonic) by immunoprecipitation of a 170-180 kDa protein with monoclonal antibody JSB-1. Both HCT-8 and T84 formed functional epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f3f62e21fe83e2c5b305914c9982b1
https://doi.org/10.1038/bjc.1991.328
https://doi.org/10.1038/bjc.1991.328
Autor:
Carla Foy, Peadar G. Noone, Pierre Yves Berclaz, Michael W. Konstan, Louis J. Boitano, Julia Emerson, Thomas A. Standaert, Michael R Knowles, Keith Hammond, Lois Brass, Pamela L. Zeitlin, Zoe Davies, Laura J H Milgram, Janice Hunter
Publikováno v:
Pediatric pulmonology. 37(5)
Patients with cystic fibrosis (CF) can be discriminated from healthy subjects by measurement of the nasal potential difference, which has become a useful outcome measure for therapies directed toward correcting defective electrolyte transport in CF.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a57a21f070ccca364709c19661e3424
https://pubmed.ncbi.nlm.nih.gov/15095320
https://pubmed.ncbi.nlm.nih.gov/15095320