Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Janice Hughes"'
Publikováno v:
The International Journal of Aging and Society. 3:37-52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39ce94ffb8878d8eaa07c29f6d025b7b
https://doi.org/10.18848/2160-1909/cgp/v03i04/35123
https://doi.org/10.18848/2160-1909/cgp/v03i04/35123
Autor:
Lars Frelin, Janice Hughes, Byung O. Lee, David R. Milich, Won-Keun Kim, Cory J. Peters, David C. Whitacre, Joyce E. Jones
Publikováno v:
Immunology. 134:434-447
Regulatory T (Treg) cells represent one of the main mechanisms of regulating self-reactive immune cells. Treg cells are thought to play a role in down-regulating immune responses to self or allogeneic antigens in the periphery. Although the function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21b789f05e2df3dcd95a63f6c338c318
https://doi.org/10.1111/j.1365-2567.2011.03502.x
https://doi.org/10.1111/j.1365-2567.2011.03502.x
Autor:
Janice Hughes, Fermin Garduno, Antony Chen, Joyce E. Jones, Florian Schödel, David R. Milich, Wendy McDowell, Phillip Goldstein, Darrell L. Peterson, Matti Sällberg, Jean-Noel Billaud
Publikováno v:
Journal of Virology. 79:13641-13655
The hepatitis B virus core protein (HBcAg) is a uniquely immunogenic particulate antigen and as such has been used as a vaccine carrier platform. The use of other hepadnavirus core proteins as vaccine carriers has not been explored. To determine whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee0ab7b1b42ca50de10280d2eaca8c1
https://doi.org/10.1128/jvi.79.21.13641-13655.2005
https://doi.org/10.1128/jvi.79.21.13641-13655.2005
Publikováno v:
Karolinska Institutet
Chronicity following hepatitis B virus (HBV) infection may be maintained by high levels of viral proteins circulating in the serum. To examine the characteristics of T cells capable of co-existing with the secreted hepatitis B e-antigen (HBeAg), T-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47f6a3e708bbf7c8ca86784afb91e94
https://doi.org/10.1016/s0166-3542(01)00174-7
https://doi.org/10.1016/s0166-3542(01)00174-7
Publikováno v:
Journal of Virology. 74:7587-7599
Chronicity after infection with the hepatitis B virus (HBV) can occur for a variety of reasons. However, once established, chronicity may be maintained by high levels of viral proteins circulating in the serum. To examine the characteristics of T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a295363c147bcacee350375450fa7e
https://doi.org/10.1128/jvi.74.16.7587-7599.2000
https://doi.org/10.1128/jvi.74.16.7587-7599.2000
Autor:
Florian Schödel, Margaret Chen, Joyce E. Jones, Darrell L. Peterson, David R. Milich, Janice Hughes
Publikováno v:
Proceedings of the National Academy of Sciences. 94:14648-14653
The hepatitis B virus (HBV) nucleocapsid or core antigen (HBcAg) is extremely immunogenic during infection and after immunization. For example, during many chronic infections, HBcAg is the only antigen capable of eliciting an immune response, and nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a858fa68dfd186e308960a9e15cb6cd
https://doi.org/10.1073/pnas.94.26.14648
https://doi.org/10.1073/pnas.94.26.14648
Publikováno v:
Journal of Biotechnology. 44:91-96
Hepatitis B virus (HBV) core antigen (HBcAg) is a highly immunogenic subviral particle. Here, we review recent progress in the use of HBcAg as a carrier moiety for heterologous epitopes. To define surface exposed and immunogenic insertion sites for f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb21240bb981d1add5c7b57d7fddb04
https://doi.org/10.1016/0168-1656(95)00118-2
https://doi.org/10.1016/0168-1656(95)00118-2
Publikováno v:
Proceedings of the National Academy of Sciences. 92:6847-6851
Helper T (Th) cells are classified as Th1 or Th2 cells by virtue of cytokine secretion and function as mediators of cellular or humoral immunity, respectively. Cytokines also regulate the differentiation of Th cells. For example, interleukin (IL)-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0bc3d1b529b7e14ff15e5442477f770
https://doi.org/10.1073/pnas.92.15.6847
https://doi.org/10.1073/pnas.92.15.6847
Publikováno v:
European Journal of Immunology. 25:1663-1672
Previous studies of hepatitis B e antigen (HBeAg)-expressing transgenic (Tg31e) mice have indicated that the degree of T cell tolerance was epitope specific. For example, T cells specific for residues 120-131 of HBeAg are profoundly tolerant, whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6213cd64ae123ccd14165e6ca129c257
https://doi.org/10.1002/eji.1830250628
https://doi.org/10.1002/eji.1830250628
Publikováno v:
Journal of Virology. 69:2776-2785
Regulatory T-helper (Th) cells have been categorized into two functional subsets, Th1 and Th2 cells, which produce distinct lymphokines. In general, Th1 cells mediate cellular immune responses and Th2 cells mediate humoral immunity. Recent serologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9f8a02c43b675fd573626327eac465
https://doi.org/10.1128/jvi.69.5.2776-2785.1995
https://doi.org/10.1128/jvi.69.5.2776-2785.1995