Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Janice E. Buss"'
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases
Campylobacter diagnosis is hampered because many laboratories continue to use traditional stool culture, which is slow and suffers false-negative results. This large multi-site study used a composite reference method consisting of a new FDA-cleared i
Publikováno v:
Journal of visualized experiments : JoVE. (157)
A culture from human stool for diagnosis of Campylobacter-based intestinal illness takes several days, a wait that taxes the fortitude of the physician and the patient. A culture is also prone to false negative results from random loss of viability d
Publikováno v:
Phytotherapy Research. 24:810-816
Type I interferons are a class of cytokines synthesized by leukocytes such as macrophages that limit viral replication. We hypothesized that one mechanism whereby Echinacea spp. extracts may enhance immunity is through modulating interferon-associate
Autor:
Channing J. Der, Adam Shutes, Emily J. Chenette, Carolyn Weinbaum, Janice E. Buss, Audrey Minden, Adrienne D. Cox, Anastacia C. Berzat
Publikováno v:
Journal of Biological Chemistry. 280:33055-33065
Wrch-1 is a Rho family GTPase that shares strong sequence and functional similarity with Cdc42. Like Cdc42, Wrch-1 can promote anchorage-independent growth transformation. We determined that activated Wrch-1 also promoted anchorage-dependent growth t
Publikováno v:
Journal of Biological Chemistry. 278:19292-19300
H-Ras displays dynamic cycles of GTP binding and palmitate turnover. GTP binding is clearly coupled to activation, but whether the palmitoylated COOH terminus participates in signaling, especially when constrained by membrane tethering, is unknown. A
Autor:
Walter H. Hsu, Janice E. Buss, Teerasak Prapong, Heather West Greenlee, Patricia A Heine, Etsuro Uemura
Publikováno v:
Experimental Neurology. 174:253-258
Amyloid beta-peptide (Abeta) has been shown to impair glucose uptake in cultured hippocampal neurons and shortens their survival time. Abeta appears to inhibit neuronal glucose uptake by activating Gs-coupled receptors and the cAMP-PKA system. In thi
Publikováno v:
Journal of Biological Chemistry. 275:22037-22047
Ha-Ras is modified by isoprenoid on Cys(186) and by reversibly attached palmitates at Cys(181) and Cys(184). Ha-Ras loses 90% of its transforming activity if Cys(181) and Cys(184) are changed to serines, implying that palmitates make important contri
Autor:
John T. Stickney, Janice E. Buss
Publikováno v:
Molecular Biology of the Cell. 11:2191-2200
Farnesylation of Ras proteins is necessary for transforming activity. Although farnesyl transferase inhibitors show promise as anticancer agents, prenylation of the most commonly mutated Ras isoform, K-Ras4B, is difficult to prevent because K-Ras4B c
Publikováno v:
Biochemistry. 38:12926-12934
H-Ras is95% membrane-bound when modified by farnesyl and palmitate, but10% membrane-bound if only farnesyl is present, implying that palmitate provides major support for membrane interaction. However the direct contribution of palmitate to H-Ras memb
Autor:
Sinisa D. Grozdanic, Markus H. Kuehn, Janice E. Buss, Daniel Zamzow, Donald S. Sakaguchi, Bas Blits, Randy H. Kardon, Matthew M. Harper
To evaluate the ability of mesenchymal stem cells (MSCs) engineered to produce and secrete brain-derived neurotrophic factor (BDNF) to protect retinal function and structure after intravitreal transplantation in a rat model of chronic ocular hyperten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3713fd1bf71d286cae1feb025b1c2ca1
https://europepmc.org/articles/PMC3175938/
https://europepmc.org/articles/PMC3175938/