Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Janice, Mayne"'
Autor:
Leyuan Li, Tong Wang, Zhibin Ning, Xu Zhang, James Butcher, Joeselle M. Serrana, Caitlin M. A. Simopoulos, Janice Mayne, Alain Stintzi, David R. Mack, Yang-Yu Liu, Daniel Figeys
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Functional redundancy is a key ecosystem property representing the fact that different taxa contribute to an ecosystem in similar ways through the expression of redundant functions. The redundancy of potential functions (or genome-level func
Externí odkaz:
https://doaj.org/article/5d3f124ec93b4a05b0683ec979cc01bb
Autor:
Yubing Liu, Maria Bilen, Marie-Michelle McNicoll, Richard A. Harris, Bensun C. Fong, Mohamed Ariff Iqbal, Smitha Paul, Janice Mayne, Krystal Walker, Jing Wang, Daniel Figeys, Ruth S. Slack
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-10 (2023)
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder leading to dementia. The hippocampus, which is one of the sites where neural stem cells reside and new neurons are born, exhibits the most significant neuronal loss in AD
Externí odkaz:
https://doaj.org/article/5885f579bf504f1894be9d65e727933b
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4228-4237 (2023)
Metaproteomics has increasingly been applied to study functional changes in the human gut microbiome. Peptide identification is an important step in metaproteomics research, with sequence database search (SDS) and spectral library search (SLS) as the
Externí odkaz:
https://doaj.org/article/5f18163573f046c98476f2cee08c0dc0
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Biobanking of live microbiota is becoming indispensable for mechanistic and clinical investigations of drug–microbiome interactions and fecal microbiota transplantation. However, there is a lack of methods to rapidly and systematically evaluate whe
Externí odkaz:
https://doaj.org/article/97ec9ff007334d97bdca433034368190
Autor:
Zhongzhi Sun, Wenju Wang, Leyuan Li, Xu Zhang, Zhibin Ning, Janice Mayne, Krystal Walker, Alain Stintzi, Daniel Figeys
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT The composition and function of the human gut microbiome are often associated with health and disease status. Sugar substitute sweeteners are widely used food additives, although many studies using animal models have linked sweetener consump
Externí odkaz:
https://doaj.org/article/e9d08aa8342442bdb97e23abc9d97adc
Autor:
Leyuan Li, Lu Chang, Xu Zhang, Zhibin Ning, Janice Mayne, Yang Ye, Alain Stintzi, Jia Liu, Daniel Figeys
Publikováno v:
Gut Microbes, Vol 11, Iss 5, Pp 1348-1361 (2020)
The understanding of the effects of compounds on the gut microbiome is limited. In particular, it is unclear whether structurally similar compounds would have similar or distinct effects on the gut microbiome. Here, we selected berberine (BBR), an is
Externí odkaz:
https://doaj.org/article/bed388db7f714f4caaab14c521aec74f
Autor:
Xu Zhang, Zhibin Ning, Janice Mayne, Yidai Yang, Shelley A. Deeke, Krystal Walker, Charles L. Farnsworth, Matthew P. Stokes, Jean-François Couture, David Mack, Alain Stintzi, Daniel Figeys
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Intestinal microbiota is increasingly reported to influence human health, but little is known on how its functions are regulated. Here the authors characterize microbiome protein acetylation and demonstrate its potential roles in shaping gut microbia
Externí odkaz:
https://doaj.org/article/8156c241c00f4392889e3f4fe586f531
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-16 (2020)
Abstract Background Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess micro
Externí odkaz:
https://doaj.org/article/acd0b02b76fa49b2bcf992e8a5839543
Autor:
Leyuan Li, James Ryan, Zhibin Ning, Xu Zhang, Janice Mayne, Mathieu Lavallée-Adam, Alain Stintzi, Daniel Figeys
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3833-3842 (2020)
Resistant starches (RS) are dietary compounds processed by the gut microbiota into metabolites, such as butyrate, that are beneficial to the host. The production of butyrate by the microbiome appears to be affected by the plant source and type of RS
Externí odkaz:
https://doaj.org/article/493916ddc3d8431f82d9d940ca8bc0d3
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-3 (2020)
Abstract Soluble low-density lipoprotein receptor (sLDLR) is the circulating ectodomain of transmembrane LDLR. Its blood level strongly correlates with that of triglycerides (TG). This correlation has eluded satisfactory explanation. Hypertriglycerid
Externí odkaz:
https://doaj.org/article/cd66b719ffe84769ad38e48174334e5c