Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Janice, Chen"'
Autor:
Peter S. Linsley, Maki Nakayama, Elisa Balmas, Janice Chen, Fariba Barahmand-pour-Whitman, Shubham Bansal, Ty Bottorff, Elisavet Serti, Cate Speake, Alberto Pugliese, Karen Cerosaletti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Human type 1 diabetes (T1D) is caused by autoimmune attack on the insulin-producing pancreatic beta cells by islet antigen-reactive T cells. How human islet antigen-reactive (IAR) CD4+ memory T cells from peripheral blood affect T1D progress
Externí odkaz:
https://doaj.org/article/66f2c80699f6498b86e42acf78ab840a
Autor:
Elisa Balmas, Janice Chen, Alex K. Hu, Hannah A. DeBerg, Mario G. Rosasco, Vivian H. Gersuk, Elisavet Serti, Cate Speake, Carla J. Greenbaum, Gerald T. Nepom, Peter S. Linsley, Karen Cerosaletti
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
Variation in the preservation of β cell function in clinical trials in type 1 diabetes (T1D) has emphasized the need to define biomarkers to predict treatment response. The T1DAL trial targeted T cells with alefacept (LFA-3–Ig) and demonstrated C-
Externí odkaz:
https://doaj.org/article/fc5124fb6eab4bc1a3e7082177f0b113
Publikováno v:
Data in Brief, Vol 50, Iss , Pp 109490- (2023)
After watching audiovisual movies, human participants produced spoken narrative recollections during functional magnetic resonance imaging (fMRI); presented here are word-level timestamps of their speech, temporally aligned to the publicly shared fMR
Externí odkaz:
https://doaj.org/article/d0c08f31342546a2a736351b67a9d0b7
Autor:
Hongmi Lee, Janice Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Naturalistic experiences often have complex structure, consisting of multiple inter-related events. Here, the authors show that the semantic and causal interconnectedness of events in narratives positively predicts memory performance and neural respo
Externí odkaz:
https://doaj.org/article/de01bcfcd69c48a38a19d77d680e1080
Autor:
Elizabeth Musz, Janice Chen
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Brain patterns measured while participants first watched a movie in the fMRI scanner, then recalled the movie’s key narrative features, demonstrate that temporal compression in individuals’ retelling of past events predicts encoding-to-recall tra
Externí odkaz:
https://doaj.org/article/204297607f9c4dfba714f23c870abbc4
Publikováno v:
Data in Brief, Vol 46, Iss , Pp 108788- (2023)
Whole-brain functional magnetic resonance imaging (fMRI) data from twenty healthy human participants were collected during naturalistic movie watching and free spoken recall tasks. Participants watched ten short (approximately 2 – 8 min) audiovisua
Externí odkaz:
https://doaj.org/article/7897b9801e564be7812db348a9c9e044
Publikováno v:
eLife, Vol 11 (2022)
The brain actively reshapes our understanding of past events in light of new incoming information. In the current study, we ask how the brain supports this updating process during the encoding and recall of naturalistic stimuli. One group of particip
Externí odkaz:
https://doaj.org/article/8ebdbff184f8427da2b9d31f213c25b6
Autor:
Samuel A. Nastase, Yun-Fei Liu, Hanna Hillman, Asieh Zadbood, Liat Hasenfratz, Neggin Keshavarzian, Janice Chen, Christopher J. Honey, Yaara Yeshurun, Mor Regev, Mai Nguyen, Claire H. C. Chang, Christopher Baldassano, Olga Lositsky, Erez Simony, Michael A. Chow, Yuan Chang Leong, Paula P. Brooks, Emily Micciche, Gina Choe, Ariel Goldstein, Tamara Vanderwal, Yaroslav O. Halchenko, Kenneth A. Norman, Uri Hasson
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-22 (2021)
Measurement(s) functional brain measurement Technology Type(s) functional magnetic resonance imaging Factor Type(s) story • native language Sample Characteristic - Organism Homo sapiens Machine-accessible metadata file describing the reported data:
Externí odkaz:
https://doaj.org/article/2b463b27ca214b4ab0dfe02db1c3ceb7
Autor:
Hongmi Lee, Janice Chen
Publikováno v:
eLife, Vol 11 (2022)
Current theory and empirical studies suggest that humans segment continuous experiences into events based on the mismatch between predicted and actual sensory inputs; detection of these ‘event boundaries’ evokes transient neural responses. Howeve
Externí odkaz:
https://doaj.org/article/a3f0de412679443fb88c766b4f209e13
Autor:
Peter S. Linsley, Fariba Barahmand-pour-Whitman, Elisa Balmas, Hannah A. DeBerg, Kaitlin J. Flynn, Alex K. Hu, Mario G. Rosasco, Janice Chen, Colin O’Rourke, Elisavet Serti, Vivian H. Gersuk, Keshav Motwani, Howard R. Seay, Todd M. Brusko, William W. Kwok, Cate Speake, Carla J. Greenbaum, Gerald T. Nepom, Karen Cerosaletti
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
Human islet antigen reactive CD4+ memory T cells (IAR T cells) play a key role in the pathogenesis of autoimmune type 1 diabetes (T1D). Using single-cell RNA sequencing (scRNA-Seq) to identify T cell receptors (TCRs) in IAR T cells, we have identifie
Externí odkaz:
https://doaj.org/article/ae78e844c0644847af1e433a33d6fd7d