Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jani Reddy Bolla"'
Autor:
Leonhard H. Urner, Idlir Liko, Hsin-Yung Yen, Kin-Kuan Hoi, Jani Reddy Bolla, Joseph Gault, Fernando Gonçalves Almeida, Marc-Philip Schweder, Denis Shutin, Svenja Ehrmann, Rainer Haag, Carol V. Robinson, Kevin Pagel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Detergents are indispensable reagents in membrane protein structural biology. Here, L. H. Urner and co-workers introduce oligoglycerol detergents (OGDs) and use native mass spectrometry to show how interactions of membrane proteins with native membra
Externí odkaz:
https://doaj.org/article/f79c32473eac49729267ef98826a98bf
Autor:
Petra Lukacik, C. David Owen, Gemma Harris, Jani Reddy Bolla, Sarah Picaud, Irfan Alibay, Joanne E. Nettleship, Louise E. Bird, Raymond J. Owens, Philip C. Biggin, Panagis Filippakopoulos, Carol V. Robinson, Martin A. Walsh
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Nontypeable Haemophilus influenzae (NTHi) is a significant pathogen in respiratory disease and otitis media. Important for NTHi survival, colonization and persistence in vivo is the Sap (sensitivity to antimicrobial peptides) ABC transporter system.
Externí odkaz:
https://doaj.org/article/e0a881dfff0a4bcfb91cb3fe4f1e1dcd
Autor:
Chih-Chia Su, Linxiang Yin, Nitin Kumar, Lei Dai, Abhijith Radhakrishnan, Jani Reddy Bolla, Hsiang-Ting Lei, Tsung-Han Chou, Jared A. Delmar, Kanagalaghatta R. Rajashankar, Qijing Zhang, Yeon-Kyun Shin, Edward W. Yu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Multidrug efflux pumps significantly contribute for bacteria resistance to antibiotics. Here the authors present the structure of Campylobacter jejuni CmeB pump combined with functional FRET assays to propose a transport mechanism where each CmeB pro
Externí odkaz:
https://doaj.org/article/51b9ec914f01445795f1807120926c42
Autor:
Fu-Lien Hsieh, Louise Turner, Jani Reddy Bolla, Carol V. Robinson, Thomas Lavstsen, Matthew K. Higgins
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Targeting of the CD36 scavenger receptor by the malaria parasite effector PfEMP1 prevents splenic clearance of infected erythrocytes. Here, the authors propose that diverse PfEMP1 achieve this by binding to a conserved phenylalanine residue in CD36 t
Externí odkaz:
https://doaj.org/article/c868d661845e470ea603b99a9105c266
Autor:
Chih-Chia Su, Jani Reddy Bolla, Nitin Kumar, Abhijith Radhakrishnan, Feng Long, Jared A. Delmar, Tsung-Han Chou, Kanagalaghatta R. Rajashankar, William M. Shafer, Edward W. Yu
Publikováno v:
Cell Reports, Vol 11, Iss 1, Pp 61-70 (2015)
Neisseria gonorrhoeae is an obligate human pathogen and the causative agent of the sexually transmitted disease gonorrhea. The control of this disease has been compromised by the increasing proportion of infections due to antibiotic-resistant strains
Externí odkaz:
https://doaj.org/article/0b3833f717574c47bdbf0366909a7641
Autor:
Hsiang-Ting Lei, Tsung-Han Chou, Chih-Chia Su, Jani Reddy Bolla, Nitin Kumar, Abhijith Radhakrishnan, Feng Long, Jared A Delmar, Sylvia V Do, Kanagalaghatta R Rajashankar, William M Shafer, Edward W Yu
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97475 (2014)
Active efflux of antimicrobial agents is one of the most important strategies used by bacteria to defend against antimicrobial factors present in their environment. Mediating many cases of antibiotic resistance are transmembrane efflux pumps, compose
Externí odkaz:
https://doaj.org/article/554d57ae66394b6cb2734f033b6ee06d
Autor:
Jani Reddy Bolla, Chih-Chia Su, Sylvia V Do, Abhijith Radhakrishnan, Nitin Kumar, Feng Long, Tsung-Han Chou, Jared A Delmar, Hsiang-Ting Lei, Kanagalaghatta R Rajashankar, William M Shafer, Edward W Yu
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97903 (2014)
Neisseria gonorrhoeae is an obligate human pathogen and the causative agent of the sexually-transmitted disease gonorrhea. The control of this disease has been compromised by the increasing proportion of infections due to antibiotic-resistant strains
Externí odkaz:
https://doaj.org/article/34a340589890428cbd269a72a7133032
Autor:
David J. Sherratt, Josh P Prince, Carol V. Robinson, Gemma L. M. Fisher, Marjorie Fournier, Jarno Mäkelä, Jani Reddy Bolla, Lidia K. Arciszewska
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Structural Maintenance of Chromosomes (SMC) complexes act ubiquitously to compact DNA linearly, thereby facilitating chromosome organization-segregation. SMC proteins have a conserved architecture, with a dimerization hinge and an ATPase head domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed48ac6007f59c0786b74b613a467adf
https://doaj.org/article/9764fc49f5434bec8e6cd75aea1813bf
https://doaj.org/article/9764fc49f5434bec8e6cd75aea1813bf
Publikováno v:
Chemical Communications. 57:10747-10750
We developed a native mass spectrometry-based approach to quantify the monomer-dimer equilibrium of the LPS transport protein LptH. We use this method to assess the potency and efficacy of an antimicrobial peptide and small molecule disruptors, obtai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2f60d4bc7537b006905adbc0f41e02
https://doi.org/10.1039/d1cc04186j
https://doi.org/10.1039/d1cc04186j
Autor:
Jacqueline M. Gulbis, Ruitao Jin, Oliver B. Clarke, Sitong He, David M. Miller, Derek R. Laver, Katrina A. Black, Paul Johnson, Christopher J. Burns, Carol V. Robinson, Jani Reddy Bolla, Monique J. Windley, Brian J. Smith, Adam P. Hill
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
The canonical mechanistic model explaining potassium channel gating is of a conformational change that alternately dilates and constricts a collar-like intracellular entrance to the pore. It is based on the premise that K+ ions maintain a complete hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669d9b4c0e835a85598473df29565c46
http://link.springer.com/article/10.1038/s41467-020-16842-0
http://link.springer.com/article/10.1038/s41467-020-16842-0