Zobrazeno 1 - 10 of 369 pro vyhledávání: '"Janghra, N."'
1
Akademický článek
ADCT-602, a Novel PBD Dimer-containing Antibody-Drug Conjugate for Treating CD22-positive Hematologic Malignancies.
Autor: Zammarchi F; ADC Therapeutics (UK) Ltd, London, United Kingdom., Havenith KE; ADC Therapeutics (UK) Ltd, London, United Kingdom., Sachini N; ADC Therapeutics (UK) Ltd, London, United Kingdom., Janghra N; ADC Therapeutics (UK) Ltd, London, United Kingdom., Chivers S; ADC Therapeutics (UK) Ltd, London, United Kingdom., Idusogie E; ADC Therapeutics America, Inc, Murray Hill, United States., Gaudio E; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Tarantelli C; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Bertelli F; AstraZeneca (MedImmune/Spirogen), London, United Kingdom., Santos K; AstraZeneca (MedImmune/Spirogen), London, United Kingdom., Tyrer P; AstraZeneca (MedImmune/Spirogen), London, United Kingdom., Corbett S; University College London, London, United Kingdom., Spriano F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Golino G; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Cascione L; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Bertoni F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland., Hartley JA; University College London, London, United Kingdom., van Berkel PH; ADC Therapeutics (UK) Ltd, London, United Kingdom.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2024 Apr 02; Vol. 23 (4), pp. 520-531.
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2
Akademický článek
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3
Correlation of utrophin levels with the dystrophin protein complex and muscle fibre regeneration in Duchenne and Becker muscular dystrophy muscle biopsies
Autor: Janghra, N, Morgan, J, Sewry, C, Wilson, F, Davies, K, Muntoni, F, Tinsley, J
Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0150818 (2016)
PLoS ONE
Duchenne muscular dystrophy is a severe and currently incurable progressive neuromuscular condition, caused by mutations in the DMD gene that result in the inability to produce dystrophin. Lack of dystrophin leads to loss of muscle fibres and a reduc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ffd1f947413c4d3f66fba41631d4831a
https://ora.ox.ac.uk/objects/uuid:925222c2-e1a6-416b-be5d-a3f3202f1e05
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4
Akademický článek
Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers.
Autor: Zammarchi F; ADC Therapeutics (UK) Limited, London, United Kingdom., Havenith KE; ADC Therapeutics (UK) Limited, London, United Kingdom., Chivers S; ADC Therapeutics (UK) Limited, London, United Kingdom., Hogg P; ADC Therapeutics (UK) Limited, London, United Kingdom., Bertelli F; AstraZeneca (MedImmune/Spirogen), Cambridge, United Kingdom., Tyrer P; AstraZeneca (MedImmune/Spirogen), Cambridge, United Kingdom., Janghra N; UCL Cancer Institute, London, United Kingdom., Reinert HW; UCL Cancer Institute, London, United Kingdom., Hartley JA; UCL Cancer Institute, London, United Kingdom., van Berkel PH; ADC Therapeutics (UK) Limited, London, United Kingdom.
Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Apr 01; Vol. 21 (4), pp. 582-593.
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5
Correlation of utrophin levels with the dystrophin protein complex and muscle fibre regeneration in Duchenne and Becker muscular dystrophy muscle biopsies
Autor: Janghra, N, Morgan, JE, Sewry, CA, Wilson, FX, Davies, KE, Muntoni, F, Tinsley, J, Cohn, R
Publikováno v: PloS one.
Duchenne muscular dystrophy is a severe and currently incurable progressive neuromuscular condition, caused by mutations in the DMD gene that result in the inability to produce dystrophin. Lack of dystrophin leads to loss of muscle fibres and a reduc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::f0c41a1220556381a6ce795b2ee1c05f
http://ora.ox.ac.uk/objects/uuid:
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6
Akademický článek
Recombinant SMN protein synergizes with spinal muscular atrophy therapy to counteract pathological motor neuron phenotypes.
Autor: Brambilla, Liliana1 (AUTHOR), Valori, Chiara F.1 (AUTHOR), Guidotti, Giulia1 (AUTHOR), Martorana, Francesca1 (AUTHOR), Sulmona, Claudia1 (AUTHOR), De Martini, Lisa Benedetta1 (AUTHOR), Canciani, Anselmo2 (AUTHOR), Fumagalli, Marco2 (AUTHOR), Talpo, Francesca3 (AUTHOR), Biella, Gerardo3 (AUTHOR), Di Pasquale, Elisa4,5 (AUTHOR), Iacobucci, Claudio6 (AUTHOR), Forneris, Federico2,7 (AUTHOR), Zhou, Haiyan8 (AUTHOR), Rossi, Daniela1 (AUTHOR) daniela.rossi@icsmaugeri.it
Publikováno v: Translational Neurodegeneration. 12/16/2024, Vol. 13 Issue 1, p1-5. 5p.
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7
Akademický článek
Golodirsen restores DMD transcript imbalance in Duchenne Muscular Dystrophy patient muscle cells.
Autor: Rossi, Rachele1,2 (AUTHOR), Torelli, Silvia1,2 (AUTHOR), Moore, Marc1,2,3 (AUTHOR), Ala, Pierpaolo1,2 (AUTHOR), Morgan, Jennifer1,2 (AUTHOR), Malhotra, Jyoti4 (AUTHOR), Muntoni, Francesco1,2 (AUTHOR) f.muntoni@ucl.ac.uk
Publikováno v: Skeletal Muscle. 11/29/2024, Vol. 14 Issue 1, p1-14. 14p.
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8
Akademický článek
Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease mice.
Autor: Caron, Nicholas S.1,2,3 (AUTHOR), Byrne, Lauren M.4 (AUTHOR), Lemarié, Fanny L.1,2,3 (AUTHOR), Bone, Jeffrey N.2,5 (AUTHOR), Aly, Amirah E.-E.1,2,3 (AUTHOR), Ko, Seunghyun1 (AUTHOR), Anderson, Christine1 (AUTHOR), Casal, Lorenzo L.1 (AUTHOR), Hill, Austin M.1 (AUTHOR), Hawellek, David J.6 (AUTHOR), McColgan, Peter7 (AUTHOR), Wild, Edward J.4 (AUTHOR), Leavitt, Blair R.1,2,3 (AUTHOR), Hayden, Michael R.1,2,3 (AUTHOR) mrh@cmmt.ubc.ca
Publikováno v: Translational Neurodegeneration. 10/8/2024, Vol. 13 Issue 1, p1-22. 22p.
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9
Akademický článek
Deletion of exons 45 to 55 in the DMD gene: from the therapeutic perspective to the in vitro model.
Autor: Poyatos-García, Javier1,2,3 (AUTHOR) javier.poyatos@uv.es, Soblechero-Martín, Patricia4 (AUTHOR), Liquori, Alessandro5,6 (AUTHOR), López-Martínez, Andrea4 (AUTHOR), Maestre, Pilar1 (AUTHOR), González-Romero, Elisa5 (AUTHOR), Vázquez-Manrique, Rafael P.7,8,9 (AUTHOR), Muelas, Nuria1,10,11 (AUTHOR), García-García, Gema7,8,9 (AUTHOR), Ohana, Jessica12 (AUTHOR), Arechavala-Gomeza, Virginia4,13 (AUTHOR), Vílchez, Juan J.1,3,10,11 (AUTHOR) juan.vilchez@uv.es
Publikováno v: Skeletal Muscle. 10/1/2024, Vol. 14 Issue 1, p1-14. 14p.
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10
Akademický článek
Targeting CD25+ lymphoma cells with the antibody-drug conjugate camidanlumab tesirine as a single agent or in combination with targeted agents.
Autor: Spriano F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Tarantelli C; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Cascione L; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland., Gaudio E; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Golino G; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Scalise L; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland., Cacciapuoti MT; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA., Zucca E; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.; Department of Oncology, Oncology Institute of Southern Switzerland, EOC, Bellinzona, Switzerland., Stathis A; Department of Oncology, Oncology Institute of Southern Switzerland, EOC, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, USI, Lugano, Switzerland., Van Berkel PH; ADC Therapeutics (UK) Ltd., London, UK., Inghirami G; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA., Zammarchi F; ADC Therapeutics (UK) Ltd., London, UK., Bertoni F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.; Department of Oncology, Oncology Institute of Southern Switzerland, EOC, Bellinzona, Switzerland.
Publikováno v: British journal of haematology [Br J Haematol] 2024 Nov; Vol. 205 (5), pp. 1873-1882. Date of Electronic Publication: 2024 Jul 30.
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