Zobrazeno 1 - 10
of 26
pro vyhledávání: '"JangEun Lee"'
Autor:
Heidi A Schreiber, Paul D Hulseberg, JangEun Lee, Jozsef Prechl, Peter Barta, Nora Szlavik, Jeffrey S Harding, Zsuzsanna Fabry, Matyas Sandor
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11453 (2010)
Mycobacterium-induced granulomas are the interface between bacteria and host immune response. During acute infection dendritic cells (DCs) are critical for mycobacterial dissemination and activation of protective T cells. However, their role during c
Externí odkaz:
https://doaj.org/article/ac4b3b5004d8408999baec4308321900
Publikováno v:
Analytical biochemistry. 633
Signaling lymphocytic activating molecule family member 1 (SLAMF1 or CD150) is a cell surface glycoprotein expressed on various immune populations, regulating cell-cell interactions, activation, differentiation, and inflammatory responses and has bee
Publikováno v:
The Journal of Immunology
Naive T cell populations are maintained in the periphery at relatively constant levels via mechanisms that control expansion and contraction and are associated with competition for homeostatic cytokines. It has been shown that in a lymphopenic enviro
Publikováno v:
The Journal of Immunology. 192:3190-3199
Fatty acids (FAs) are essential constituents of cell membranes, signaling molecules, and bioenergetic substrates. Because CD8+ T cells undergo both functional and metabolic changes during activation and differentiation, dynamic changes in FA metaboli
Publikováno v:
Journal of Neuroimmunology. 219:33-37
We investigated the anti-inflammatory effects of minocycline in EAE, an animal model of MS. Minocycline, administered for two weeks after the clinical onset, significantly decreased the cumulative and mean clinical scores of EAE. This was associated
Autor:
Zsuzsanna Fabry, Alla L. Zozulya, Sonja Ortler, Christian Weidenfeller, Matyas Sandor, Heinz Wiendl, JangEun Lee
Publikováno v:
The Journal of Neuroscience. 29:140-152
Dendritic cells (DCs) appear in higher numbers within the CNS as a consequence of inflammation associated with autoimmune disorders, such as multiple sclerosis, but the contribution of these cells to the outcome of disease is not yet clear. Here, we
Publikováno v:
The Journal of Immunology. 181:6201-6212
Multiple sclerosis and an animal model resembling multiple sclerosis, experimental autoimmune encephalomyelitis (EAE), are inflammatory demyelinating diseases of the CNS that are suppressed by systemic mycobacterial infection in mice and BCG vaccinat
Autor:
JangEun Lee, Melissa G. Harris, Matyas Sandor, Zsuzsanna Fabry, Erika Heninger, Benjamin D. Clarkson
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461401056
Dendritic cells (DCs) are a heterogeneous group of professional antigen presenting cells that lie in a nexus between innate and adaptive immunity because they recognize and respond to danger signals and subsequently initiate and regulate effector T-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0c30a2c634ceb1ef86ca5c3cce214b
https://doi.org/10.1007/978-1-4614-0106-3_18
https://doi.org/10.1007/978-1-4614-0106-3_18
Mycobacterial suppression of central nervous system (CNS) autoimmunity has been demonstrated in various experimental models, epidemiological studies, and clinical trials. Recent studies have led to an increased understanding of the cellular and molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20349965c20b1a5e50b9003e57e836d
https://europepmc.org/articles/PMC2875250/
https://europepmc.org/articles/PMC2875250/
Publikováno v:
Journal of neuropathology and experimental neurology. 68(6)
Multiple sclerosis is an immune-mediated demyelinating disease, with axonal loss underlying long-term progressive disability. In this study, we have analyzed axonal and myelin pathology in a chronic relapsing-remitting experimental autoimmune encepha