Zobrazeno 1 - 10
of 420
pro vyhledávání: '"Jang Yang, Chang"'
Autor:
Hao-Wei Lee, Szu-Jung Chen, Kuen-Jer Tsai, Kuei-Sen Hsu, Yi-Fan Chen, Chih-Hua Chang, Hsiao-Han Lin, Wen-Yun Hsueh, Hsing-Pang Hsieh, Yueh-Feng Lee, Huai-Chueh Chiang, Jang-Yang Chang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-23 (2024)
Abstract Background Cathepsin S (CTSS) is a cysteine protease that played diverse roles in immunity, tumor metastasis, aging and other pathological alterations. At the cellular level, increased CTSS levels have been associated with the secretion of p
Externí odkaz:
https://doaj.org/article/cb18c5ca1d994f6798eb6006543573e6
Autor:
Chih-Peng Lin, Shu-Hui Wu, Tzu-Yin Lin, Chia-Hui Chu, Leu-Wei Lo, Ching-Chuan Kuo, Jang-Yang Chang, Szu-Chun Hsu, Bor-Sheng Ko, Ming Yao, Jong-Kai Hsiao, Shih-Wei Wang, Dong-Ming Huang
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106945- (2023)
Multidrug resistance (MDR) is a major challenge in cancer chemotherapy. Nanoparticles as drug delivery systems (DDSs) show promise for MDR cancer therapy. However, current DDSs require sophisticated design and construction based on xenogeneic nanomat
Externí odkaz:
https://doaj.org/article/86f572430e7749389f8fa9beb3b0a6e4
Autor:
Sheng-Yen Hsiao, Shang-Mei Weng, Jenn-Ren Hsiao, Yi-Ying Wu, Jia-En Wu, Chia-Hao Tung, Wan-Lin Shen, Shu-Fang Sun, Wen-Tsung Huang, Cheng-Yao Lin, Shang-Hung Chen, Tse-Ming Hong, Yuh-Ling Chen, Jang-Yang Chang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Lymph node and distant metastasis contribute to poor outcomes in patients with oral squamous cell carcinoma (OSCC). The mechanisms regulating cancer migration and invasion play a key role in OSCC. Methods We determined migration a
Externí odkaz:
https://doaj.org/article/0aac509a7647492fab204db355a88715
Autor:
Vidhya Tangeda, Yu Kang Lo, Ananth Ponneri Babuharisankar, Han-Yu Chou, Cheng-Liang Kuo, Yung-Hsi Kao, Alan Yueh-Luen Lee, Jang-Yang Chang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-15 (2022)
Abstract Mitochondria are the major organelles in sensing cellular stress and inducing the response for cell survival. Mitochondrial Lon has been identified as an important stress protein involved in regulating proliferation, metastasis, and apoptosi
Externí odkaz:
https://doaj.org/article/0a53eb478acb419f8e5f10f9c857b202
Autor:
Cheng‐Chih Huang, Yu‐Chu Su, Chan‐Chi Chang, Wei‐Ting Lee, Chun‐Yen Ou, Yuan‐Hua Wu, Shang‐Yin Wu, Yu‐Hsuan Lai, Jehn‐Shyun Huang, Ken‐Chung Chen, Wei‐Ting Hsueh, Sen‐Tien Tsai, Chia‐Jui Yen, Jang‐Yang Chang, Mei‐Ling Tsai, Chen‐Lin Lin, Ya‐Ling Weng, Han‐Chien Yang, Yu‐Shan Chen, Jenn‐Ren Hsiao, Jeffrey S. Chang
Publikováno v:
Cancer Medicine, Vol 10, Iss 12, Pp 4075-4086 (2021)
ABSTRACT Human papillomavirus (HPV) is recognized as a major cause of oropharyngeal cancer (OPC) in Western countries. Less is known regarding its contribution to the OPC occurring in Asia. The current study aimed to investigate the association betwe
Externí odkaz:
https://doaj.org/article/1a946623eddb4546bba076c88fb54598
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract S-1, an oral pyrimidine fluoride-derived agent, is effective against various cancers. Sorafenib, an oral multikinase inhibitor, was found to prolong the survival of various cancers and enhance the cytotoxicity of chemotherapeutic agents. We
Externí odkaz:
https://doaj.org/article/4f7d321634ba464c96a8af513e32056b
Autor:
Yu-Lin Chen, Yi-Chen Yen, Chuan-Wei Jang, Ssu-Han Wang, Hsin-Ting Huang, Chung-Hsing Chen, Jenn-Ren Hsiao, Jang-Yang Chang, Ya-Wen Chen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Ephrin type-A receptor 10 (EPHA10) has been implicated as a potential target for breast and prostate cancer therapy. However, its involvement in oral squamous cell carcinoma (OSCC) remains unclear. We demonstrated that EPHA10 supports in viv
Externí odkaz:
https://doaj.org/article/21cf012a84ff48269dd235e08c02781b
Autor:
Shine-Gwo Shiah, Jenn-Ren Hsiao, Hsiao-Ju Chang, Yuan-Ming Hsu, Guan-Hsun Wu, Hsuan-Yu Peng, Sung-Tau Chou, Ching-Chuan Kuo, Jang-Yang Chang
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-13 (2020)
Abstract Background Epigenetic silencing of retinoic acid (RA) signaling-related genes have been linked with the pathogenesis and clinical outcome in oral squamous cell carcinoma (OSCC) carcinogenesis. However, the precise mechanisms underlying the a
Externí odkaz:
https://doaj.org/article/8eb2b9f459944aa48d0ec169c427c2d6
Autor:
Yi-Hong Liu, Yu-Lian Chen, Ting-Yu Lai, Ying-Chieh Ko, Yu-Fu Chou, Peir-Rong Chen, Jenn-Ren Hsiao, Jang-Yang Chang, Shine-Gwo Shiah, Jeng-Woei Lee, Jia-Ling Yang, Su-Fang Lin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPartial epithelial-mesenchymal transition (p-EMT) is a distinct clinicopathological feature prevalent in oral cavity tumors of The Cancer Genome Atlas. Located at the invasion front, p-EMT cells require additional support from the tumor str
Externí odkaz:
https://doaj.org/article/c5c66b95121f48e0859d1730794ad5c4
Autor:
Yue-Zhi Lee, Hsing-Yu Hsu, Cheng-Wei Yang, Yi-Ling Lin, Sui-Yuan Chang, Ruey-Bing Yang, Jian-Jong Liang, Tai-Ling Chao, Chun-Che Liao, Han-Chieh Kao, Jang-Yang Chang, Huey-Kang Sytwu, Chiung-Tong Chen, Shiow-Ju Lee
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 342 (2023)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/ba68c145557544469ba467e8ddbc8c57