Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jang Kyoung Kim"'
Publikováno v:
Journal of Controlled Release. 215:82-90
Effective intracellular level of a platinum anti-cancer drug, cisplatin, following repeated injections can be decreased either by the active efflux via ATP pump or by interactions with glutathione and metallothionein. Cisplatin in cytoplasm preferabl
Publikováno v:
Scientific Reports
SCIENTIFIC REPORTS(7)
SCIENTIFIC REPORTS(7)
A subset of phagocytes including inflammatory monocytes in blood migrate and give rise to macrophages in inflammatory tissues which generated the idea that blood monocytes are the therapeutic targets for drug delivery. Fc gamma receptor I (CD64) is a
Publikováno v:
Journal of Controlled Release. 259:e119-e120
Autor:
Kwang Suk Lim, Eun-Jung Kim, Jong Tae Kim, Yong-Hee Kim, Wonjin Lee, Ki Dong Park, Hye Jung Kim, Myoung Hun Kim, Jang Kyoung Kim, Young Il Yang
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 215
Myocardial infarction (MI) results in the substantial loss of functional cardiomyocytes, which frequently leads to intractable heart disorders. Cardiac stem cells (CSCs) that retain the capacity to replace all cardiac cells might be a promising strat
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 194
Diabetes is the fastest growing metabolic disease that fails to utilize glucose properly due to insulin deficiency or insulin resistance. Although several limited studies demonstrated non-invasive means of protein delivery, major hurdles for commerci
Autor:
Seok Beom Young, Jang Kyoung Kim, Hyung-Jin Kim, Jee Young Chung, Jong Hwan Lee, Yong-Hee Kim
Publikováno v:
Archives of pharmacal research. 37(1)
A wide variety of delivery systems have been developed and many products based on the drug delivery technology are commercially available. The development of controlled-release technologies accelerated new dosage form design by altering pharmacokinet
Autor:
Yong-Hee Kim, Kwang Suk Lim, Hyung-Jin Kim, Young-Wook Won, Partho P. Adhikary, Jang Kyoung Kim
Publikováno v:
Nature materials. 13(12)
Commercial anti-obesity drugs acting in the gastrointestinal tract or the central nervous system have been shown to have limited efficacy and severe side effects. Anti-obesity drug development is thus focusing on targeting adipocytes that store exces
Dual-mode enhancement of metallothionein protein with cell transduction and retention peptide fusion
Autor:
Kwang Suk Lim, Yong-Hee Kim, Myoung Hwa Lim, Seong Eon Ryu, Jang Kyoung Kim, Young Cheol Kang, Ji Won Chae, So Mi Kim, Youngmi Kim Pak, Young-Wook Won, Eun Jeong Park
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 171(2)
Protein transduction domains (PTDs), also known as cell-penetrating peptides (CPPs), have been developed as effective systems for delivering bio-active cargos such as proteins, genes and particles. Further improvements on cell-specific targeting, int
Autor:
Yong-Hee Kim, Jang Kyoung Kim, Min Ji Cha, Kwang Suk Lim, Ji Won Chae, Taiyoun Rhim, Ki-Chul Hwang, Eun Jeong Park
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 169(3)
Ischemic heart diseases caused by insufficient oxygen supply to the cardiac muscle require pharmaceutical agents for the prevention of the progress and recurrence. Metallothionein (MT) has a potential as a protein therapeutic for the treatment of thi
Publikováno v:
Pharmaceutical research. 29(2)
To develop low-molecular-weight methylcellulose (LMw MC)-based gel/Pluronic F127 micelle combination system for local and sustained delivery of docetaxel (DTX).LMw MC and Pluronic F127 were used to formulate an injectable thermo-reversible gel/micell