Zobrazeno 1 - 10
of 1 255
pro vyhledávání: '"Janey, P. A."'
Autor:
Santiago Diaz-Torres, Weixiong He, Regina Yu, IGGC International Glaucoma Genetics Consortium, Anthony P. Khawaja, Christopher J. Hammond, Pirro G. Hysi, Louis R. Pasquale, Yeda Wu, Michiaki Kubo, Masato Akiyama, Tin Aung, Ching-Yu Cheng, Chiea Chuen Khor, Peter Kraft, Jae H. Kang, Alex W. Hewitt, David A. Mackey, Jamie E. Craig, Janey L. Wiggs, Jue-Sheng Ong, Stuart MacGregor, Puya Gharahkhani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Primary open-angle glaucoma typically presents as two subtypes. This study aimed to elucidate the shared and distinct genetic architectures of normal-tension (NTG) and high-tension glaucoma (HTG), motivated by the need to develop intraocular
Externí odkaz:
https://doaj.org/article/922ae413070b45558acecb577bd65aed
Autor:
Kimberly L. Meidenbauer, Kathryn E. Schertz, Peiyuan Li, Ashish Sharma, Tiara R. Freeman, Elizabeth A. Janey, Andrew J. Stier, Anya L. Samtani, Kathryn Gehrke, Marc G. Berman
Publikováno v:
BMC Psychology, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract The effects of heat exposure on negative affect are thought to be central to the observed relationships between hot summer days and deleterious outcomes, such as violent crime or mental health crises. As these relationships are likely to be
Externí odkaz:
https://doaj.org/article/f3a1a229136841e7a4a0295f3dee9c68
Autor:
Janey Sewell, Charlie Witzel, David Dunn, Fiona Lampe, Fiona Burns, Peter Weatherburn, Sheena McCormack, Leanne McCabe, Alec Miners, Valentina Cambiano, Roger Pebody, Roy Trevelion, Nadia Hanum, Andrew Phillips, Alison Rodger
Publikováno v:
Programme Grants for Applied Research, Vol 12, Iss 08 (2024)
Background Rates of human immunodeficiency virus diagnoses in UnitedKingdom men who have sex with men were at a 10-year high in 2014; many recent infections indicated ongoing transmission. There was a need to increase testing rates, reduce late diagn
Externí odkaz:
https://doaj.org/article/b2e31e0bcd9e4f2bbf2727662b827e5d
Collective behavior of people in large groups and emergent crowd dynamics can have dangerous and disastrous results when panic is introduced. These events can be caused by emergency situations such as fires in a large building or a stampeding effect
Externí odkaz:
http://arxiv.org/abs/2212.08149
Autor:
Fangyu Lin, Ying Li, Jiaxing Wang, Sandra Jardines, Rebecca King, Micah A. Chrenek, Janey L. Wiggs, Jeffrey H. Boatright, Eldon E. Geisert
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Pou6f2 is a genetic connection between central corneal thickness (CCT) in the mouse and a risk factor for developing primary open-angle glaucoma. POU6F2 is also a risk factor for several conditions in humans, including glaucoma, myopia, and
Externí odkaz:
https://doaj.org/article/a9be1903fee4473f833493ebaafeb929
Autor:
Mohammad Kermansaravi, Sonja Chiappetta, Chetan Parmar, Scott A. Shikora, Gerhard Prager, Teresa LaMasters, Jaime Ponce, Lilian Kow, Abdelrahman Nimeri, Shanu N. Kothari, Edo Aarts, Syed Imran Abbas, Ahmad Aly, Ali Aminian, Ahmad Bashir, Estuardo Behrens, Helmuth Billy, Miguel A. Carbajo, Benjamin Clapp, Jean-Marc Chevallier, Ricardo V. Cohen, Jerome Dargent, Bruno Dillemans, Silvia L. Faria, Manoel Galvao Neto, Pierre Y. Garneau, Khaled Gawdat, Ashraf Haddad, Mohamad Hayssam ElFawal, Kelvin Higa, Jaques Himpens, Farah Husain, Matthew M. Hutter, Kazunori Kasama, Radwan Kassir, Amir Khan, Mousa Khoursheed, Matthew Kroh, Marina S. Kurian, Wei-Jei Lee, Ken Loi, Kamal Mahawar, Corrigan L. McBride, Hazem Almomani, John Melissas, Karl Miller, Monali Misra, Mario Musella, C. Joe Northup, Mary O’Kane, Pavlos K. Papasavas, Mariano Palermo, Richard M. Peterson, Ralph Peterli, Luis Poggi, Janey S. A. Pratt, Aayad Alqahtani, Almino C. Ramos, Karl Rheinwalt, Rui Ribeiro, Ann M. Rogers, Bassem Safadi, Paulina Salminen, Sergio Santoro, Nathaniel Sann, John D. Scott, Asim Shabbir, Stephanie Sogg, Erik Stenberg, Michel Suter, Antonio Torres, Surendra Ugale, Ramon Vilallonga, Cunchuan Wang, Rudolf Weiner, Natan Zundel, Luigi Angrisani, Maurizio De Luca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Metabolic and bariatric surgery (MBS) is widely considered the most effective option for treating obesity, a chronic, relapsing, and progressive disease. Recently, the American Society of Metabolic and Bariatric Surgery (ASMBS) and the Inter
Externí odkaz:
https://doaj.org/article/d11a127484f24f42a7a29a6327c26a74
Autor:
Andrew R. Hamel, Wenjun Yan, John M. Rouhana, Aboozar Monovarfeshani, Xinyi Jiang, Puja A. Mehta, Jayshree Advani, Yuyang Luo, Qingnan Liang, Skanda Rajasundaram, Arushi Shrivastava, Katherine Duchinski, Sreekar Mantena, Jiali Wang, Tavé van Zyl, Louis R. Pasquale, Anand Swaroop, Puya Gharahkhani, Anthony P. Khawaja, Stuart MacGregor, International Glaucoma Genetics Consortium (IGGC), Rui Chen, Veronique Vitart, Joshua R. Sanes, Janey L. Wiggs, Ayellet V. Segrè
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Primary open-angle glaucoma (POAG), characterized by retinal ganglion cell death, is a leading cause of irreversible blindness worldwide. However, its molecular and cellular causes are not well understood. Elevated intraocular pressure (IOP)
Externí odkaz:
https://doaj.org/article/7f45f11f740249d881e78d06fd091c4e
Autor:
Megan Yu, BS, Hannah H. Hwang, BS, Janey L. Wiggs, MD, PhD, Louis R. Pasquale, MD, Jae H. Kang, ScD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 3, Pp 100436- (2024)
Topic: This systematic review and meta-analysis summarizes the existing evidence for the association of diabetes mellitus (DM) and exfoliation syndrome (XFS). Clinical Relevance: Understanding and quantifying these associations may aid clinical guide
Externí odkaz:
https://doaj.org/article/1fb000f1b63447b488bdfa7c5a35b4b5
Autor:
Skanda Rajasundaram, Nazlee Zebardast, Puja Mehta, Anthony P. Khawaja, Alasdair Warwick, Katherine Duchinski, Stephen Burgess, Dipender Gill, Ayellet V. Segrè, Janey Wiggs
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background In primary open-angle glaucoma (POAG), lowering intraocular pressure (IOP) is the only proven way of slowing vision loss. Schlemm’s canal (SC) is a hybrid vascular and lymphatic vessel that mediates aqueous humour drainage from
Externí odkaz:
https://doaj.org/article/3d439713257e4f38a7603dcd3644a025
Autor:
Wendy W. Liu, Tyler G. Kinzy, Jessica N. Cooke Bailey, Zihe Xu, Pirro Hysi, Janey L. Wiggs, NEIGHBORHOOD Consortium
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Although glaucoma is a disease modulated by eye pressure, the mechanisms of pressure sensing in the eye are not well understood. Here, we investigated associations between mechanosensitive ion channel gene variants and primary open-angle gla
Externí odkaz:
https://doaj.org/article/71e99a7591124c8bbe41fc3b922d5713