Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Janette N Zara"'
Autor:
Feng Chen, Xinli Zhang, Shan Sun, Janette N Zara, Xuan Zou, Robert Chiu, Cymbelin T Culiat, Kang Ting, Chia Soo
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24638 (2011)
NELL-1 is a novel secreted protein associated with premature fusion of cranial sutures in craniosynostosis that has been found to promote osteoblast cell differentiation and mineralization. Our previous study showed that Runx2, the key transcription
Externí odkaz:
https://doaj.org/article/e63793711a3e4232b7ff3140bac5ecb4
Autor:
Eric Chen, Chia Soo, Richard Song, Janette N. Zara, Kang Ting, Zhihe Zhao, Xinli Zhang, Wenlu Jiang, Zhong Zheng, Chenshuang Li, Soonchul Lee
Publikováno v:
Journal of Cellular and Molecular Medicine
Hypertrophic scarring is a major postoperative complication which leads to severe disfigurement and dysfunction in patients and usually requires multiple surgical revisions due to its high recurrence rates. Excessive‐mechanical‐loading across wou
Autor:
Jia Shen, A. Simon Turner, Emily A. Berthiaume, Soonchul Lee, Janette N. Zara, Chenchao Wang, Hsin Chuan Pan, Howard B. Seim, Xinli Zhang, Kang Ting, Alan Nguyen, Jin Hee Kwak, Chia Soo
Publikováno v:
The American Journal of Pathology. 187:1485-1495
Multiple case reports using recombinant human bone morphogenetic protein-2 (rhBMP-2) have reported complications. However, the local adverse effects of rhBMP-2 application are not well documented. In this report we show that, in addition to promoting
Autor:
Kevork Khadarian, Greg Asatrian, James B. Zhang, Aaron W. James, Kang Ting, Jia Shen, Stephanie Ho, Chia Soo, Janette N. Zara, Hyun Ju Kim
Publikováno v:
Tissue Engineering Part A. 19:2390-2401
Bone-morphogenetic protein 2 (BMP2) is currently the only Food and Drug Administration-approved osteoinductive growth factor used in clinical settings for bone regeneration and repair. However, the use of BMP2 is encumbered by numerous clinical compl
Autor:
Kang Ting, Khalid Al Hezaimi, Cun-Yu Wang, Jia Chang, Janette N. Zara, Min Lee, Weiping Zou, Chia Soo, Xiaohong Chen, Fei Liu, Benjamin M. Wu, David J. Mooney
Publikováno v:
Proceedings of the National Academy of Sciences. 110:9469-9474
Mesenchymal stem cell (MSC)-based transplantation is a promising therapeutic approach for bone regeneration and repair. In the realm of therapeutic bone regeneration, the defect or injured tissues are frequently inflamed with an abnormal expression o
Autor:
Kevin S. Lee, Doug Carpenter, Zhong Zheng, Yi Liu, Chunling Wang, Ching Yun Hsu, Janette N. Zara, Ronald K. Siu, Lloyd S. Miller, Kang Ting, Xinli Zhang, Chia Soo, Donnalisa E. Soofer
Publikováno v:
Biomaterials. 33:8745-8756
Implant-associated bacterial infections are one of the most serious complications in orthopedic surgery. Treatment of these infections often requires multiple operations, device removal, long-term systemic antibiotics, and extended rehabilitation, an
Autor:
Janette N. Zara, Greg Asatrian, Shen Pang, Aaron W. James, David A. Stoker, Xinli Zhang, Kang Ting, Alireza Hourfar, Benjamin M. Wu, Alan Nguyen, Bruno Péault, Mirko Corselli, Silva Megerdichian, Asal Askarinam, Chia Soo, Ann M. Zhou
Publikováno v:
Stem Cells Translational Medicine. 1:673-684
Adipose tissue is an ideal mesenchymal stem cell (MSC) source, as it is dispensable and accessible with minimal morbidity. However, the stromal vascular fraction (SVF) of adipose tissue is a heterogeneous cell population, which has disadvantages for
Autor:
Zhong Zheng, Kang Ting, Yi Liu, Xinli Zhang, Shen Pang, Jia Jian, Joyce Wang, Chia Soo, Michael F. Chiang, Wei Yin, Janette N. Zara
Publikováno v:
Biomaterials. 33:5821-5831
Pluripotent and/or multipotent stem cell-based therapeutics are a vital component of tissue engineering and regenerative medicine. The generation or isolation of safer and readily available stem cell sources will significantly aid clinical applicatio
Autor:
Janette N. Zara, Angel Pan, Chia Soo, Michael F. Chiang, Aaron W. James, Xinli Zhang, Kang Ting
Publikováno v:
Biochemical and Biophysical Research Communications. 411:126-131
A theoretical inverse relationship has long been postulated for osteogenic and adipogenic differentiation (bone versus adipose tissue differentiation). This inverse relationship in theory at least partially underlies the clinical entity of osteoporos
Autor:
Wei Yin, Chia Soo, Franklin Chu, Kang Ting, Anh Le, Janette N. Zara, Zhong Zheng, Shen Pang, Hooman Khorasani, Joyce Wang, Xinli Zhang, Calvin Nguyen
Publikováno v:
Journal of Investigative Dermatology. 131:769-778
Fibromodulin (FMOD), a small leucine-rich proteoglycan, mediates scarless fetal skin wound repair through, in part, transforming growth factor-β (TGF-β) modulation. Using an adult fmod -null ( fmod -/- ) mouse model, this study further elucidates t