Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Janette M. Tack"'
Publikováno v:
Bioconjugate Chemistry. 13:474-480
A 27-kDa TASP protein, T(5)Msc(103-151), that was derived from the cytoplasmic domain (amino acid residues 103-151) of the MscL ion channel of M. tuberculosis was synthesized by ketoxime-forming chemoselective ligation between a template molecule car
Autor:
Vincent Gueriguian, Gerd G. Kochendoerfer, Shiah-Yun Chen, Maia Carnevali, Ting Kong, Jason M. Williams, James A. Bradburne, Xavier Paliard, Haiyan Shao, Janette M. Tack, E. Neil Cagle, Milan M. Crnogorac, Les P. Miranda, David Tumelty
Publikováno v:
Journal of the American Chemical Society. 127(5)
A synthetic strategy that allows for the site-specific attachment of polymers such as poly(ethylene glycol) (PEG) to protein pharmaceuticals is described. PEG was attached to a 67-amino acid fully synthetic CCL-5 (RANTES) analogue at its GAG binding