Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Janette Berglez"'
Publikováno v:
Protein Expression and Purification. 41:355-362
The tri-functional enzyme of Saccharomyces cerevisiae dihydroneopterin aldolase (DHNA)—dihydropterin pyrophosphokinase (PPPK)—dihydropteroate synthase (DHPS) catalyzes three sequential steps in folate biosynthesis. A cDNA encoding the PPPK and DH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ffb3bbf9fc6d4855141634d832dda4
https://doi.org/10.1016/j.pep.2005.02.003
https://doi.org/10.1016/j.pep.2005.02.003
Publikováno v:
International Journal for Parasitology. 34:95-100
Mutations in Plasmodium falciparum dihydropteroate synthase have been linked to resistance to the antimalarial drug, sulfadoxine, which competes with the dihydropteroate synthase substrate, p-aminobenzoate. In an effort to evaluate the role of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e038fe0487caa276716c060e4ca1e2bc
https://doi.org/10.1016/j.ijpara.2003.09.009
https://doi.org/10.1016/j.ijpara.2003.09.009
Publikováno v:
Microbial Drug Resistance. 9:249-255
The enzyme dihydropteroate synthase (DHPS) is an important target for sulfa drugs in both prokaryotic and eukaryotic microbes. However, the understanding of DHPS function and the action of antifolates in eukaryotes has been limited due to technical d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09e05955d0b743c85c9c21ddef9b725
https://doi.org/10.1089/107662903322286454
https://doi.org/10.1089/107662903322286454
Autor:
Carol Hopkins Sibley, Ian Macreadie, Eleanor G. Hankins, Onisha Patel, Ann M Bayly, Laura A. Castelli, Peter Coloe, Janette Berglez
Publikováno v:
FEMS Microbiology Letters. 204:387-390
Saccharomyces cerevisiae mutants deficient in folate synthesis have been constructed and employed to study the utilisation of exogenous folates in yeast. One mutant specifically lacked dihydropteroate synthase while the second lacked dihydrofolate sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b125c6f32e4b268787f7b1e80573df
https://doi.org/10.1111/j.1574-6968.2001.tb10915.x
https://doi.org/10.1111/j.1574-6968.2001.tb10915.x
Autor:
Janette Berglez, Sonia A. Sankovich, Cyril C. Curtain, Laura A. Castelli, Ian Macreadie, Stuart Smith
Publikováno v:
Biochemical and Biophysical Research Communications. 264:287-290
HIV-1 Vpr is a virion-associated protein that can cause growth arrest when produced inside the cell but when added externally it can cause cell death. Employing the yeast model system, the C-terminal domain, in particular the sequence HFRIGCRHSRIG (V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04493f125729f43dea65278ffa421da
https://doi.org/10.1006/bbrc.1999.1511
https://doi.org/10.1006/bbrc.1999.1511
Autor:
Michael C. Lawrence, Ian Macreadie, Ross Fernley, Peter Iliades, Patricia A. Pilling, Janette Berglez
Publikováno v:
Journal of molecular biology. 348(3)
In Saccharomyces cerevisiae and other fungi, the enzymes dihydroneopterin aldolase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK) and dihydropteroate synthase (DHPS) are encoded by a polycistronic gene that is translated into a single po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333cbb252c2b40fbbc9940e3c2f71eb4
https://pubmed.ncbi.nlm.nih.gov/15826662
https://pubmed.ncbi.nlm.nih.gov/15826662